Hzf

Summary

Gene Symbol: Hzf
Description: zinc finger protein 385A
Alias: Hzf, Zfp385, Znf385a, zinc finger protein 385A, hematopoietic zinc finger protein, zinc finger protein 385
Species: mouse
Products:     Hzf

Top Publications

  1. Hidaka M, Caruana G, Stanford W, Sam M, Correll P, Bernstein A. Gene trapping of two novel genes, Hzf and Hhl, expressed in hematopoietic cells. Mech Dev. 2000;90:3-15 pubmed
    Using an expression gene trapping strategy, we have identified and characterized two novel hematopoietic genes, Hzf and Hhl...
  2. Kimura Y, Hart A, Hirashima M, Wang C, Holmyard D, Pittman J, et al. Zinc finger protein, Hzf, is required for megakaryocyte development and hemostasis. J Exp Med. 2002;195:941-52 pubmed
    Using an expression gene trapping strategy, we recently identified a novel gene, hematopoietic zinc finger (Hzf), which encodes a protein containing three C(2)H(2)-type zinc fingers that is predominantly expressed in megakaryocytes...
  3. Iijima T, Imai T, Kimura Y, Bernstein A, Okano H, Yuzaki M, et al. Hzf protein regulates dendritic localization and BDNF-induced translation of type 1 inositol 1,4,5-trisphosphate receptor mRNA. Proc Natl Acad Sci U S A. 2005;102:17190-5 pubmed
    ..Here, we identified hematopoietic zinc finger (Hzf) as a trans-acting factor that regulates the dendritic mRNA localization of the type 1 inositol 1,4,5-trisphosphate ..
  4. Das S, Raj L, Zhao B, Kimura Y, Bernstein A, Aaronson S, et al. Hzf Determines cell survival upon genotoxic stress by modulating p53 transactivation. Cell. 2007;130:624-37 pubmed
    ..We show here that hematopoietic zinc finger (Hzf), a zinc-finger-containing p53 target gene, modulates p53 transactivation functions in an autoregulatory feedback ..
  5. Iijima T, Ogura H, Takatsuki K, Kawahara S, Wakabayashi K, Nakayama D, et al. Impaired motor functions in mice lacking the RNA-binding protein Hzf. Neurosci Res. 2007;58:183-9 pubmed
    ..Previously, we reported that hematopoietic zinc finger (Hzf) is one of the neuronal RNA-binding proteins that regulate these processes...
  6. Kawagishi H, Wakoh T, Uno H, Maruyama M, Moriya A, Morikawa S, et al. Hzf regulates adipogenesis through translational control of C/EBPalpha. EMBO J. 2008;27:1481-90 pubmed publisher
    ..Here, we show that Hzf (haematopoietic zinc-finger), a previously identified p53 transcriptional target, regulates C/EBPalpha expression...
  7. Nakamura H, Kawagishi H, Watanabe A, Sugimoto K, Maruyama M, Sugimoto M. Cooperative role of the RNA-binding proteins Hzf and HuR in p53 activation. Mol Cell Biol. 2011;31:1997-2009 pubmed publisher
    The RNA-binding protein Hzf (hematopoietic zinc finger) plays important roles in mRNA translation in cerebellar Purkinje cells and adipocytes...
  8. Tsuboi D, Kuroda K, Tanaka M, Namba T, Iizuka Y, Taya S, et al. Disrupted-in-schizophrenia 1 regulates transport of ITPR1 mRNA for synaptic plasticity. Nat Neurosci. 2015;18:698-707 pubmed publisher
    ..to screen for DISC1 interactors and identified several RNA-binding proteins, such as hematopoietic zinc finger (HZF), that act as components of RNA-transporting granules...