Htr1e

Summary

Gene Symbol: Htr1e
Description: 5-hydroxytryptamine (serotonin) receptor 1E
Alias: Htr1ea, 5-hydroxytryptamine (serotonin) receptor 1E
Species: mouse

Top Publications

  1. Amlaiky N, Ramboz S, Boschert U, Plassat J, Hen R. Isolation of a mouse "5HT1E-like" serotonin receptor expressed predominantly in hippocampus. J Biol Chem. 1992;267:19761-4 pubmed
    ..Our results therefore demonstrate that the 5HT1E receptors constitute a heterogeneous family of receptors. ..
  2. McAllister G, Charlesworth A, Snodin C, Beer M, Noble A, Middlemiss D, et al. Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype. Proc Natl Acad Sci U S A. 1992;89:5517-21 pubmed
    ..The excellent correlation observed between the pharmacology of the expressed receptor encoded by AC1 and the human brain 5HT1E binding site confirms that AC1 encodes a 5HT1E receptor and establishes a fifth 5HT1-like receptor subtype. ..
  3. Charles C, Abler A, Lau L. cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein. Oncogene. 1992;7:187-90 pubmed
    ..Using affinity-purified antibodies, we have identified the 3CH134 protein in serum-stimulated Balb/c 3T3 cells and determined that it has a short half-life. ..
  4. Weissman J, Ma J, Essex A, Gao Y, Burstein E. G-protein-coupled receptor-mediated activation of rap GTPases: characterization of a novel Galphai regulated pathway. Oncogene. 2004;23:241-9 pubmed
    ..A constitutively active mutant of Galphai2 also mediated Ras/rap-dependent responses. These data indicate that GPCRs coupled to pertussis-toxin-sensitive G-proteins activate Rap through a Galpha subunit, C3G, and Src-dependent pathway. ..