Gene Symbol: Hmg20a
Description: high mobility group 20A
Alias: 1200004E06Rik, 5730490E10Rik, Hmgxb1, Ibraf, high mobility group protein 20A, HMG box-containing protein 20A, HMG domain-containing protein HMGX1, inhibitor of BRAF35
Wynder C, Hakimi M, Epstein J, Shilatifard A, Shiekhattar R. Recruitment of MLL by HMG-domain protein iBRAF promotes neural differentiation. Nat Cell Biol. 2005;7:1113-7 pubmed
..Here, we show that the BRAF35 family member inhibitor of BRAF35 (iBRAF) activates REST-responsive genes through the modulation of histone methylation...
Artegiani B, Labbaye C, Sferra A, Quaranta M, Torreri P, Macchia G, et al
. The interaction with HMG20a/b proteins suggests a potential role for beta-dystrobrevin in neuronal differentiation. J Biol Chem. 2010;285:24740-50 pubmed publisher
..Among the positive clones, one encodes iBRAF/HMG20a, a high mobility group (HMG)-domain protein that activates REST (RE-1 silencing transcription factor)-responsive ..
Davies R, Wagstaff K, McLaughlin E, Loveland K, Jans D. The BRCA1-binding protein BRAP2 can act as a cytoplasmic retention factor for nuclear and nuclear envelope-localizing testicular proteins. Biochim Biophys Acta. 2013;1833:3436-3444 pubmed publisher
..for the first time of three of these: the high mobility group (HMG)-box-domain-containing chromatin component HMG20A, nuclear mitotic apparatus protein NuMA1 and synaptic nuclear envelope protein SYNE2...
Sumoy L, Carim L, Escarceller M, Nadal M, Gratacos M, Pujana M, et al
. HMG20A and HMG20B map to human chromosomes 15q24 and 19p13.3 and constitute a distinct class of HMG-box genes with ubiquitous expression. Cytogenet Cell Genet. 2000;88:62-7 pubmed
..We describe HMG20A and HMG20B, two novel human HMG box-containing genes, discovered within the EURO-IMAGE Consortium full-length cDNA ..
Ceballos Chávez M, Rivero S, García Gutiérrez P, Rodríguez Paredes M, Garcia Dominguez M, Bhattacharya S, et al
. Control of neuronal differentiation by sumoylation of BRAF35, a subunit of the LSD1-CoREST histone demethylase complex. Proc Natl Acad Sci U S A. 2012;109:8085-90 pubmed publisher
..Sumoylation of Braf35 is required for this antineurogenic activity. We also show that iBraf, a paralogue of Braf35, forms heterodimers with Braf35...