Gene Symbol: Hmg20a
Description: high mobility group 20A
Alias: 1200004E06Rik, 5730490E10Rik, Hmgxb1, Ibraf, high mobility group protein 20A, HMG box-containing protein 20A, HMG domain-containing protein HMGX1, inhibitor of BRAF35
Species: mouse
Products:     Hmg20a

Top Publications

  1. Wynder C, Hakimi M, Epstein J, Shilatifard A, Shiekhattar R. Recruitment of MLL by HMG-domain protein iBRAF promotes neural differentiation. Nat Cell Biol. 2005;7:1113-7 pubmed
    ..Here, we show that the BRAF35 family member inhibitor of BRAF35 (iBRAF) activates REST-responsive genes through the modulation of histone methylation...
  2. Artegiani B, Labbaye C, Sferra A, Quaranta M, Torreri P, Macchia G, et al. The interaction with HMG20a/b proteins suggests a potential role for beta-dystrobrevin in neuronal differentiation. J Biol Chem. 2010;285:24740-50 pubmed publisher
    ..Among the positive clones, one encodes iBRAF/HMG20a, a high mobility group (HMG)-domain protein that activates REST (RE-1 silencing transcription factor)-responsive ..
  3. Davies R, Wagstaff K, McLaughlin E, Loveland K, Jans D. The BRCA1-binding protein BRAP2 can act as a cytoplasmic retention factor for nuclear and nuclear envelope-localizing testicular proteins. Biochim Biophys Acta. 2013;1833:3436-3444 pubmed publisher
    ..for the first time of three of these: the high mobility group (HMG)-box-domain-containing chromatin component HMG20A, nuclear mitotic apparatus protein NuMA1 and synaptic nuclear envelope protein SYNE2...
  4. Sumoy L, Carim L, Escarceller M, Nadal M, Gratacos M, Pujana M, et al. HMG20A and HMG20B map to human chromosomes 15q24 and 19p13.3 and constitute a distinct class of HMG-box genes with ubiquitous expression. Cytogenet Cell Genet. 2000;88:62-7 pubmed
    ..We describe HMG20A and HMG20B, two novel human HMG box-containing genes, discovered within the EURO-IMAGE Consortium full-length cDNA ..
  5. Ceballos Chávez M, Rivero S, García Gutiérrez P, Rodríguez Paredes M, Garcia Dominguez M, Bhattacharya S, et al. Control of neuronal differentiation by sumoylation of BRAF35, a subunit of the LSD1-CoREST histone demethylase complex. Proc Natl Acad Sci U S A. 2012;109:8085-90 pubmed publisher
    ..Sumoylation of Braf35 is required for this antineurogenic activity. We also show that iBraf, a paralogue of Braf35, forms heterodimers with Braf35...