Gene Symbol: Hist1h2bg
Description: histone cluster 1, H2bg
Alias: histone H2B type 1-C/E/G, histone 1, H2bg
Das R, Burke T, Plow E. Histone H2B as a functionally important plasminogen receptor on macrophages. Blood. 2007;110:3763-72 pubmed
..Taken together, these data suggest that multiple Plg-Rs do contribute to Plg binding to macrophages, and among these, H2B plays a very prominent and functionally important role. ..
Xu Y, Wang Y, Besnard V, Ikegami M, Wert S, Heffner C, et al
. Transcriptional programs controlling perinatal lung maturation. PLoS ONE. 2012;7:e37046 pubmed publisher
..The present study systemically mapped key regulators, bioprocesses, and transcriptional networks controlling lung maturation, providing the basis for new therapeutic strategies to enhance lung function in preterm infants. ..
Wang Z, Tisovec R, DeBry R, Frey M, Matera A, Marzluff W. Characterization of the 55-kb mouse histone gene cluster on chromosome 3. Genome Res. 1996;6:702-14 pubmed
..One of the histone H2b genes has lost the stem-loop sequence characteristic of the replication-dependent histone mRNAs and encodes only polyadenylated mRNAs. ..
Fernandez Capetillo O, Allis C, Nussenzweig A. Phosphorylation of histone H2B at DNA double-strand breaks. J Exp Med. 2004;199:1671-7 pubmed
..Our results broaden the spectrum of histone modifications that constitute the DNA damage "histone code" and suggest a model for the underlying chromatin structure within damage-induced foci. ..
Odegard V, Kim S, Anderson S, Shlomchik M, Schatz D. Histone modifications associated with somatic hypermutation. Immunity. 2005;23:101-10 pubmed
..These findings indicate that SHM and CSR trigger distinct DNA damage responses and identify a novel histone modification pattern for SHM consisting of H2B(Ser14P) in the absence of gammaH2AX. ..
Ballif B, Carey G, Sunyaev S, Gygi S. Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. J Proteome Res. 2008;7:311-8 pubmed
..To measure the conservation of phosphorylated tyrosines and their surrounding residues, we constructed a computational pipeline and identified patterns of conservation within the signature of phosphotyrosine. ..