Gene Symbol: Gulp1
Description: GULP, engulfment adaptor PTB domain containing 1
Alias: 3110030A04Rik, 5730529O06Rik, CED-6, Ced6, GULP, Gulp-2, PTB domain-containing engulfment adapter protein 1, CED 6, PTB domain adapter protein CED-6, cell death protein 6 homolog
Species: mouse
Products:     Gulp1

Top Publications

  1. Su H, Nakada Tsukui K, Tosello Trampont A, Li Y, Bu G, Henson P, et al. Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP). J Biol Chem. 2002;277:11772-9 pubmed
    ..The molecular details of the engulfment of apoptotic cells are not fully understood. ced-6 and its human homologue gulp, encode an adapter protein, whose function in engulfment is highly evolutionarily conserved; however, the upstream ..
  2. Osada Y, Sunatani T, Kim I, Nakanishi Y, Shiratsuchi A. Signalling pathway involving GULP, MAPK and Rac1 for SR-BI-induced phagocytosis of apoptotic cells. J Biochem. 2009;145:387-94 pubmed publisher
    ..a yeast two-hybrid analysis and a cell-free binding assay indicated that SR-BI binds to engulfment adapter protein (GULP) using the C-terminal intracellular domain...
  3. Banerjee H, Hawkins Z, Johnson T, Eley S, Alikhan A, McDaniel M, et al. Identification of a mouse orthologue of the CED-6 gene of Caenorhabditis elegans. Plasmid. 2003;49:30-3 pubmed
    ..Thus in this study we report the identification of a novel C. elegans CED-6-like orthologue in mouse, which has probable apoptotic like function. ..
  4. Sullivan C, Scheib J, Ma Z, Dang R, Schafer J, Hickman F, et al. The adaptor protein GULP promotes Jedi-1-mediated phagocytosis through a clathrin-dependent mechanism. Mol Biol Cell. 2014;25:1925-36 pubmed publisher
    ..Here we demonstrate that Jedi-1 associates with GULP, the mammalian homologue of CED-6, an adaptor protein required for phagocytosis mediated by the nematode engulfment ..