Gm4836

Summary

Gene Symbol: Gm4836
Description: predicted gene 4836
Alias: Xlr-related, meiosis regulated
Species: mouse
Products:     Gm4836

Top Publications

  1. Calenda A, Allenet B, Escalier D, Bach J, Garchon H. The meiosis-specific Xmr gene product is homologous to the lymphocyte Xlr protein and is a component of the XY body. EMBO J. 1994;13:100-9 pubmed
    ..The Xmr protein provides a new tool for the investigation of sex chromosome behaviour during meiosis in mammals. ..
  2. Di Carlo A, Travia G, De Felici M. The meiotic specific synaptonemal complex protein SCP3 is expressed by female and male primordial germ cells of the mouse embryo. Int J Dev Biol. 2000;44:241-4 pubmed
    ..This strongly supports the hypothesis that primordial germ cells are programmed to enter meiosis unrespective of the sex and that foetal testis produces a factor that inhibits such programme. ..
  3. Escalier D, Eloy L, Garchon H. Sex-specific gene expression during meiotic prophase I: Xlr (X linked, lymphocyte regulated), not its male homologue Xmr (Xlr related, meiosis regulated), is expressed in mouse oocytes. Biol Reprod. 2002;67:1646-52 pubmed
    ..In addition, because of the localization of the Xlr sequence family on the mouse X chromosome, the human equivalent of Xlr is a candidate gene for premature ovarian failure. ..
  4. Costa Y, Speed R, Gautier P, Semple C, Maratou K, Turner J, et al. Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?. Hum Mol Genet. 2006;15:2324-34 pubmed
    ..The presence of MAEL in these critical compartments of male germ cells and its interactions provide a link suggesting the involvement of the miRNA pathway in MSUC...