Genomes and Genes
Gene Symbol: Exoc4
Description: exocyst complex component 4
Alias: C78892, Sec8, Sec8l1, exocyst complex component 4, SEC8-like 1, exocyst complex component Sec8
- Olsen O, Moore K, Fukata M, Kazuta T, Trinidad J, Kauer F, et al. Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex. J Cell Biol. 2005;170:1127-34 pubmed..These findings are consistent with a model whereby the MALS-CASK-liprin-alpha complex recruits components of the synaptic release machinery to adhesive proteins of the active zone. ..
- Lyons P, Peck G, Kettenbach A, Gerber S, Roudaia L, Lienhard G. Insulin stimulates the phosphorylation of the exocyst protein Sec8 in adipocytes. Biosci Rep. 2009;29:229-35 pubmed publisher..b>Sec8 is a component of the exocyst complex that has been previously implicated in GLUT4 trafficking...
- Bolis A, Coviello S, Visigalli I, Taveggia C, Bachi A, Chishti A, et al. Dlg1, Sec8, and Mtmr2 regulate membrane homeostasis in Schwann cell myelination. J Neurosci. 2009;29:8858-70 pubmed publisher..We here report that, in Schwann cells, Dlg1 also interacts with kinesin 13B (kif13B) and Sec8, which are involved in vesicle transport and membrane tethering in polarized cells, respectively...
- Ozcelik M, Cotter L, Jacob C, Pereira J, Relvas J, Suter U, et al. Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves. J Neurosci. 2010;30:4120-31 pubmed publisher..In addition, pals1 is required for the normal polarized localization of the vesicular markers sec8 and syntaxin4, and for the distribution of E-cadherin and myelin proteins PMP22 and MAG at the plasma membrane...
- Chernyshova Y, Leshchyns ka I, Hsu S, Schachner M, Sytnyk V. The neural cell adhesion molecule promotes FGFR-dependent phosphorylation and membrane targeting of the exocyst complex to induce exocytosis in growth cones. J Neurosci. 2011;31:3522-35 pubmed publisher..NCAM promotes FGF receptor-mediated phosphorylation of two tyrosine residues in the sec8 subunit of the exocyst complex and is required for efficient recruitment of the exocyst complex to growth cones...
- Liu J, Qi Y, Li S, Hsu S, Saadat S, Hsu J, et al. CREG1 Interacts with Sec8 to Promote Cardiomyogenic Differentiation and Cell-Cell Adhesion. Stem Cells. 2016;34:2648-2660 pubmed publisher..Furthermore, CREG1 directly interacts with Sec8 of the exocyst complex, which tethers vesicles to the plasma membrane...