Gene Symbol: Esp1
Description: exocrine gland secreted peptide 1
Alias: EG619517, Gm6084, exocrine gland-secreted peptide 1, esp1, exocrine gland-secreting peptide 1
Species: mouse
Products:     Esp1

Top Publications

  1. Haga S, Hattori T, Sato T, Sato K, Matsuda S, Kobayakawa R, et al. The male mouse pheromone ESP1 enhances female sexual receptive behaviour through a specific vomeronasal receptor. Nature. 2010;466:118-22 pubmed publisher
    ..Exocrine gland-secreting peptide 1 (ESP1) is a 7-kDa peptide that is released into male tear fluids and stimulates vomeronasal sensory neurons in female ..
  2. Kimoto H, Haga S, Sato K, Touhara K. Sex-specific peptides from exocrine glands stimulate mouse vomeronasal sensory neurons. Nature. 2005;437:898-901 pubmed
    ..This peptide, which we named exocrine gland-secreting peptide 1 (ESP1), is encoded by a gene from a previously unrecognized large family clustered in proximity to the class I major ..
  3. Kimoto H, Sato K, Nodari F, Haga S, Holy T, Touhara K. Sex- and strain-specific expression and vomeronasal activity of mouse ESP family peptides. Curr Biol. 2007;17:1879-84 pubmed
    Male mice secrete exocrine-gland-secreting peptide 1 (ESP1) from the extraorbital lacrimal gland into tear fluid [1]...
  4. Karn R, Laukaitis C. The roles of gene duplication, gene conversion and positive selection in rodent Esp and Mup pheromone gene families with comparison to the Abp family. PLoS ONE. 2012;7:e47697 pubmed publisher
    ..We compare and contrast the evolutionary histories of all three mouse pheromone gene families in light of their proposed functions in mouse communication. ..
  5. Yoshinaga S, Sato T, Hirakane M, Esaki K, Hamaguchi T, Haga Yamanaka S, et al. Structure of the mouse sex peptide pheromone ESP1 reveals a molecular basis for specific binding to the class C G-protein-coupled vomeronasal receptor. J Biol Chem. 2013;288:16064-72 pubmed publisher
    Exocrine gland-secreting peptide 1 (ESP1) is a sex pheromone that is released in male mouse tear fluids and enhances female sexual receptive behavior...