Gene Symbol: Eid1
Description: EP300 interacting inhibitor of differentiation 1
Alias: 2610002K20Rik, Cri1, EID-1, ORF12, PNAS-22, PTD014, EP300-interacting inhibitor of differentiation 1, CREBBP/EP300 inhibitory protein 1, E1A-like inhibitor of differentiation 1, eid1
Species: mouse
Products:     Eid1

Top Publications

  1. Carim L, Sumoy L, Andreu N, Estivill X, Escarceller M. Identification and expression analysis of C15orf3, a novel gene on chromosome 15q21.1-->q21.2. Cytogenet Cell Genet. 2000;88:330-2 pubmed
    ..EST database searching revealed the presence of C15orf3 homologs in rat and mouse. C15orf3 was mapped to chromosome 15q21.1-->q21.2 using the Stanford G3 radiation hybrid panel. ..
  2. Ji A, Dao D, Chen J, MacLellan W. EID-2, a novel member of the EID family of p300-binding proteins inhibits transactivation by MyoD. Gene. 2003;318:35-43 pubmed
    ..These data suggest that EID-1 and -2 represent a novel family of proteins that negatively regulate differentiation through a p300-dependent mechanism. ..
  3. Lizcano F, Vargas D. EID1-induces brown-like adipocyte traits in white 3T3-L1 pre-adipocytes. Biochem Biophys Res Commun. 2010;398:160-5 pubmed publisher
    ..In the present work, we show that over-expression of EID1 (E1A-like inhibitor of differentiation), an inhibitor of muscle cell differentiation, reduces PPARgamma ligand-..
  4. Diez E, Zhu L, Teatero S, Paquet M, Roy M, Loredo Osti J, et al. Identification and characterization of Cri1, a locus controlling mortality during Citrobacter rodentium infection in mice. Genes Immun. 2011;12:280-90 pubmed publisher
    ..We have named this new host resistance locus Cri1 (Citrobacter rodentium infection 1)...
  5. Ye B, Dai Z, Liu B, Wang R, Li C, Huang G, et al. Pcid2 inactivates developmental genes in human and mouse embryonic stem cells to sustain their pluripotency by modulation of EID1 stability. Stem Cells. 2014;32:623-35 pubmed publisher
    ..Pcid2 deficiency causes early embryonic lethality before the blastocyst stage. Pcid2 associates with EID1 and is present in the CBP/p300-EID1 complex in the ESCs...
  6. Chen X, Du Z, Li X, Wang L, Wang F, Shi W, et al. Protein Palmitoylation Regulates Neural Stem Cell Differentiation by Modulation of EID1 Activity. Mol Neurobiol. 2016;53:5722-36 pubmed publisher
    ..Moreover, the results show that palmitoylation modified E1A-like inhibitor of differentiation one (EID1) and this modification regulated EID1 degradation and CREB-binding protein (CBP)/p300 histone acetyltransferase ..
  7. Båvner A, Johansson L, Toresson G, Gustafsson J, Treuter E. A transcriptional inhibitor targeted by the atypical orphan nuclear receptor SHP. EMBO Rep. 2002;3:478-84 pubmed
    ..Here, we describe the isolation of mouse E1A-like inhibitor of differentiation 1 (EID1) as a candidate coinhibitor for SHP...
  8. Park Y, Park K, Shong M, Lee S, Lee Y, Choi H. EID-1 interacts with orphan nuclear receptor SF-1 and represses its transactivation. Mol Cells. 2007;24:372-7 pubmed
    ..EID-1 is expressed in the mouse testis, and its expression decreases during testis development. The results of the present study suggest that EID-1 can act as a repressor, regulating the function of SF-1. ..
  9. Teatero S, Thomassin J, Zhu L, Diez E, Malo D, Gruenheid S. The Cri1 locus is the common genetic cause of susceptibility to Citrobacter rodentium infection in C3H and FVB mouse strains. Gut Microbes. 2011;2:173-7 pubmed
    ..rodentium infection. We have named the locus Citrobacter rodentium infection 1 (Cri1). Here we show that Cri1 also controls susceptibility to C...