Genomes and Genes
Gene Symbol: Dusp9
Description: dual specificity phosphatase 9
Alias: Dusp4, Mpk4, Pyst3, dual specificity protein phosphatase 9, dual-specificity MAP kinase phosphatase 4
- Urness L, Li C, Wang X, Mansour S. Expression of ERK signaling inhibitors Dusp6, Dusp7, and Dusp9 during mouse ear development. Dev Dyn. 2008;237:163-9 pubmed..otic development, we surveyed the expression domains of the three ERK-specific DUSP transcripts, Dusp6, Dusp7, and Dusp9, in the embryonic mouse ear...
- Dickinson R, Delavaine L, Cejudo Marín R, Stewart G, Staples C, Didmon M, et al. Phosphorylation of the kinase interaction motif in mitogen-activated protein (MAP) kinase phosphatase-4 mediates cross-talk between protein kinase A and MAP kinase signaling pathways. J Biol Chem. 2011;286:38018-26 pubmed publisherMAP kinase phosphatase 4 (DUSP9/MKP-4) plays an essential role during placental development and is one of a subfamily of three closely related cytoplasmic dual-specificity MAPK phosphatases, which includes the ERK-specific enzymes DUSP6/..
- Finelli M, Murphy K, Chen L, Zou H. Differential phosphorylation of Smad1 integrates BMP and neurotrophin pathways through Erk/Dusp in axon development. Cell Rep. 2013;3:1592-606 pubmed publisher..Together, the BMP and neurotrophin pathways form a tightly regulated signaling network with a balanced ratio of Erk1/2 and pErk1/2 to direct the precise connections between sensory neurons and peripheral targets. ..
- Niedzielska M, Raffi F, Tel J, Muench S, Jozefowski K, Alati N, et al. Selective Expression of the MAPK Phosphatase Dusp9/MKP-4 in Mouse Plasmacytoid Dendritic Cells and Regulation of IFN-Î² Production. J Immunol. 2015;195:1753-62 pubmed publisher..In this study, we identified the MAPK phosphatase Dusp9/MKP-4 by transcriptome analysis as selectively expressed in pDCs, but not cDCs...