Dusp26

Summary

Gene Symbol: Dusp26
Description: dual specificity phosphatase 26 (putative)
Alias: 2310043K02Rik, Skrp3, dual specificity protein phosphatase 26, dual-specificity phosphatase SKRP3
Species: mouse
Products:     Dusp26

Top Publications

  1. Romรก Mateo C, Rios P, Tabernero L, Attwood T, Pulido R. A novel phosphatase family, structurally related to dual-specificity phosphatases, that displays unique amino acid sequence and substrate specificity. J Mol Biol. 2007;374:899-909 pubmed
    ..Our findings predict characteristic functional motifs for the diverse members of the DSP families of PTPs and provide insights into the functional properties of DSPs of unknown function. ..
  2. Rardin M, Wiley S, Murphy A, Pagliarini D, Dixon J. Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane. J Biol Chem. 2008;283:15440-50 pubmed publisher
    ..This work rigorously demonstrates the unique location of two highly similar DSPs on opposing sides of the mitochondrial inner membrane...
  3. Pazin D, Gamer L, Cox K, Rosen V. Molecular profiling of synovial joints: use of microarray analysis to identify factors that direct the development of the knee and elbow. Dev Dyn. 2012;241:1816-26 pubmed publisher
    ..Our microarray analyses provides a new resource for further investigation of the pathways involved in the morphogenesis of specific synovial joints. ..
  4. Kim H, Lee H, Oh Y, Choi S, Hong S, Kim H, et al. The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth. Nat Commun. 2014;5:3351 pubmed publisher
    ..AK2 forms a complex with dual-specificity phosphatase 26 (DUSP26) phosphatase and stimulates DUSP26 activity independently of its AK activity...
  5. Shi Y, Ma I, Patel R, Shang X, Zhao Y, Cheng J, et al. NSC-87877 inhibits DUSP26 function in neuroblastoma resulting in p53-mediated apoptosis. Cell Death Dis. 2015;6:e1841 pubmed publisher
    b>Dual specificity protein phosphatase 26 (DUSP26) is overexpressed in high-risk neuroblastoma (NB) and contributes to chemoresistance by inhibiting p53 function. In vitro, DUSP26 has also been shown to effectively inhibit p38 MAP kinase...

Scientific Experts