Gene Symbol: Dusp15
Description: dual specificity phosphatase-like 15
Alias: AI851682, LMW-DSP10, T-DSP10, dual specificity protein phosphatase 15, dual specificity protein phosphatase T-DSP10
Alonso A, Narisawa S, Bogetz J, Tautz L, Hadzic R, Huynh H, et al
. VHY, a novel myristoylated testis-restricted dual specificity protein phosphatase related to VHX. J Biol Chem. 2004;279:32586-91 pubmed
The human DUSP15 gene encodes an uncharacterized 235-amino acid member of the subfamily of small dual specificity protein phosphatases related to the Vaccinia virus VH1 phosphatase...
Sun M, Mondal K, Patel V, Horner V, Long A, Cutler D, et al
. Multiplex Chromosomal Exome Sequencing Accelerates Identification of ENU-Induced Mutations in the Mouse. G3 (Bethesda). 2012;2:143-50 pubmed publisher
Schmidt F, Van Den Eijnden M, Pescini Gobert R, Saborio G, Carboni S, Alliod C, et al
. Identification of VHY/Dusp15 as a regulator of oligodendrocyte differentiation through a systematic genomics approach. PLoS ONE. 2012;7:e40457 pubmed publisher
..This effort led to the identification of Dusp15/VHY, a PTP previously believed to be expressed only in testis, as being transcriptionally regulated during OL ..
Muth K, Piefke S, Weider M, Sock E, Hermans Borgmeyer I, Wegner M, et al
. The Dual-specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes. Glia. 2016;64:2120-2132 pubmed publisher
..Sox10 and Myrf also cooperate in the activation of the gene coding for the dual specificity protein phosphatase Dusp15 (also known as VHY) during this process...
Aoki N, Aoyama K, Nagata M, Matsuda T. A growing family of dual specificity phosphatases with low molecular masses. J Biochem. 2001;130:133-40 pubmed
..Taken together, it is conceivable that a distinct class of low molecular mass DSPs is present and plays a role in dephosphorylating unknown molecules other than MAP kinases. ..
Rodriguez Molina J, Lopez Anido C, Ma K, Zhang C, Olson T, Muth K, et al
. Dual specificity phosphatase 15 regulates Erk activation in Schwann cells. J Neurochem. 2017;140:368-382 pubmed publisher
..We chose one such gene encoding Dual specificity phosphatase 15 (Dusp15) for further analysis in Schwann cell signaling...