Gene Symbol: Dpf3
Description: D4, zinc and double PHD fingers, family 3
Alias: 2810403B03Rik, 6530402L11Rik, BAF45C, C78788, CERD4, cer-d4, zinc finger protein DPF3, BRG1-associated factor 45C, D4 zinc and double PHD finger family 3, cerebellum D4, zinc finger protein cer-d4
Lange M, Kaynak B, Forster U, Tönjes M, Fischer J, Grimm C, et al
. Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex. Genes Dev. 2008;22:2370-84 pubmed publisher
..We present DPF3, a new epigenetic key factor for heart and muscle development characterized by a double PHD finger...
Chestkov A, Baka I, Kost M, Georgiev G, Buchman V. The d4 gene family in the human genome. Genomics. 1996;36:174-7 pubmed
..The conservation of d4 proteins from nematodes to vertebrates suggests that they have a general importance, but a diversity of d4 proteins expressed in vertebrate nervous systems suggests that some family members have special functions. ..
Ninkina N, Mertsalov I, Kulikova D, Alimova Kost M, Simonova O, Korochkin L, et al
. Cerd4, third member of the d4 gene family: expression and organization of genomic locus. Mamm Genome. 2001;12:862-6 pubmed
..We cloned and characterized the third member of this gene family, cer-d4 (Cerd4), from chicken and mouse cDNA libraries...
Lessard J, Wu J, Ranish J, Wan M, Winslow M, Staahl B, et al
. An essential switch in subunit composition of a chromatin remodeling complex during neural development. Neuron. 2007;55:201-15 pubmed
..As neural progenitors exit the cell cycle, these subunits are replaced by the homologous BAF45b, BAF45c, and BAF53b. BAF45a/53a subunits are necessary and sufficient for neural progenitor proliferation...
Staahl B, Tang J, Wu W, Sun A, Gitler A, Yoo A, et al
. Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways. J Neurosci. 2013;33:10348-61 pubmed publisher
Di Giovanni V, Walker K, Bushnell D, Schaefer C, Sims Lucas S, Puri P, et al
. Fibroblast growth factor receptor-Frs2Î± signaling is critical for nephron progenitors. Dev Biol. 2015;400:82-93 pubmed publisher
..Thus, Fgfr1 and Fgfr2 have synergistic roles in maintaining nephron progenitors; furthermore, Fgfr signaling in nephron progenitors appears to be mediated predominantly by Frs2Î±. ..
Shapira S, Lim H, Rajakumari S, Sakers A, Ishibashi J, Harms M, et al
. EBF2 transcriptionally regulates brown adipogenesis via the histone reader DPF3 and the BAF chromatin remodeling complex. Genes Dev. 2017;31:660-673 pubmed publisher
..We identified the histone reader protein DPF3 as a brown fat-selective component of the BAF complex that was required for brown fat gene programming and ..