Gene Symbol: Decr2
Description: 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal
Alias: peroxisomal 2,4-dienoyl-CoA reductase, 2,4-dienoyl-CoA reductase 2
Species: mouse
Products:     Decr2

Top Publications

  1. Geisbrecht B, Liang X, Morrell J, Schulz H, Gould S. The mouse gene PDCR encodes a peroxisomal delta(2), delta(4)-dienoyl-CoA reductase. J Biol Chem. 1999;274:25814-20 pubmed
    ..We conclude that this protein resides within the peroxisome matrix and therefore represents the first mammalian peroxisomal Delta(2),Delta(4)-dienoyl-CoA reductase to be characterized at the molecular level. ..
  2. De Nys K, Meyhi E, Mannaerts G, Fransen M, Van Veldhoven P. Characterisation of human peroxisomal 2,4-dienoyl-CoA reductase. Biochim Biophys Acta. 2001;1533:66-72 pubmed
    ..Hence, the reductase does not seem to constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. The reduction of docosaheptaenoyl-CoA, however, was severely decreased in the presence of albumin. ..