Dear1

Summary

Gene Symbol: Dear1

Description: dual endothelin 1/angiotensin II receptor 1 homolog (rat)

Alias: Dear, dual endothelin 1/angiotensin II receptor 1 homolog

Species: mouse

Embryonic lethality in Dear gene-deficient mice: new player in angiogenesis
Victoria L M Herrera
Department of Medicine, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Massachusetts, USA
Physiol Genomics 23:257-68
Endogenous endothelin-1 is required for cardiomyocyte survival in vivo
Xiao Song Zhao
Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA
Circulation 114:830-7
Sex-specific hippocampus-dependent cognitive deficits and increased neuronal autophagy in DEspR haploinsufficiency in mice
Victoria L M Herrera
Department of Medicine, Section of Molecular Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
Physiol Genomics 35:316-29

Embryonic lethality in Dear gene-deficient mice: new player in angiogenesis
Victoria L M Herrera
Department of Medicine, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Massachusetts, USA
Physiol Genomics 23:257-68
The dual endothelin-1/angiotensin II receptor (Dear) binds endothelin-1 (ET-1) and angiotensin II (ANG II) with equal affinities in the Dahl S/JRHS rat strain...
Endogenous endothelin-1 is required for cardiomyocyte survival in vivo
Xiao Song Zhao
Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA
Circulation 114:830-7
..This cardiac-protective effect is mediated by paracrine ET-1 modulation of TNF-related apoptosis, in part through upregulation of NF-kappaB signaling...
Sex-specific hippocampus-dependent cognitive deficits and increased neuronal autophagy in DEspR haploinsufficiency in mice
Victoria L M Herrera
Department of Medicine, Section of Molecular Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
Physiol Genomics 35:316-29
....