Cyp2c55

Summary

Gene Symbol: Cyp2c55
Description: cytochrome P450, family 2, subfamily c, polypeptide 55
Alias: 2010318C06Rik, cytochrome P450 2C55, CYPIIC55, cyp2c55, cytochrome P450, 2c55
Species: mouse
Products:     Cyp2c55

Top Publications

  1. Wang H, Zhao Y, Bradbury J, Graves J, Foley J, Blaisdell J, et al. Cloning, expression, and characterization of three new mouse cytochrome p450 enzymes and partial characterization of their fatty acid oxidation activities. Mol Pharmacol. 2004;65:1148-58 pubmed
    ..5-megabase region on chromosome 19. We cloned three novel mouse CYP2C cDNAs (designated CYP2C50, CYP2C54, and CYP2C55) from mouse heart, liver, and colon, respectively...
  2. van Waterschoot R, Rooswinkel R, Wagenaar E, van der Kruijssen C, van Herwaarden A, Schinkel A. Intestinal cytochrome P450 3A plays an important role in the regulation of detoxifying systems in the liver. FASEB J. 2009;23:224-31 pubmed publisher
    CYP3A4 is an important xenobiotic metabolizing enzyme. We previously found that CYP2C55 is highly up-regulated in Cyp3a(-/-) mice...
  3. Chen S, Lu W, Yueh M, Rettenmeier E, Liu M, Paszek M, et al. Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia. Proc Natl Acad Sci U S A. 2017;114:E1432-E1440 pubmed publisher
    ..These findings provide a mechanism of NCoR1 in intestinal homeostasis during development and provide a key link to those events that control developmental repression of UGT1A1 and hyperbilirubinemia. ..