Cuta

Summary

Gene Symbol: Cuta
Description: cutA divalent cation tolerance homolog
Alias: 0610039D01Rik, 1810022E02Rik, 1810060C03Rik, 2700094G22Rik, AI326454, protein CutA, brain acetylcholinesterase putative membrane anchor, divalent cation tolerant protein CUTA
Species: mouse
Products:     Cuta

Top Publications

  1. Liang D, Nunes Tavares N, Xie H, Carvalho S, Bon S, Massoulié J. Protein CutA undergoes an unusual transfer into the secretory pathway and affects the folding, oligomerization, and secretion of acetylcholinesterase. J Biol Chem. 2009;284:5195-207 pubmed publisher
    The mammalian protein CutA was first discovered in a search for the membrane anchor of mammalian brain acetylcholinesterase (AChE). It was co-purified with AChE, but it is distinct from the real transmembrane anchor protein, PRiMA...
  2. Liang D, Carvalho S, Bon S, Massoulié J. Unusual transfer of CutA into the secretory pathway, evidenced by fusion proteins with acetylcholinesterase. FEBS J. 2009;276:4473-82 pubmed publisher
    The mouse CutA protein exists as long and short components of 20 and 15 kDa, produced by the use of different in-frame ATGs initiation codons, and by proteolytic cleavage...
  3. Hou P, Liu G, Zhao Y, Shi Z, Zheng Q, Bu G, et al. Role of copper and the copper-related protein CUTA in mediating APP processing and Aβ generation. Neurobiol Aging. 2015;36:1310-5 pubmed publisher
    ..Abnormal copper homeostasis also contributes to AD pathogenesis. Recently, we find that a copper-related protein, CutA divalent cation tolerance homolog of Escherichia coli (CUTA), interacts with the β-secretase β-site APP ..