Ctnnal1

Summary

Gene Symbol: Ctnnal1
Description: catenin (cadherin associated protein), alpha-like 1
Alias: ACRP, AI616177, AW545119, C86009, Catnal1, alpha-catulin, alpha-catenin related protein, catenin alpha-like 1, catenin alpha-like protein 1
Species: mouse
Products:     Ctnnal1

Top Publications

  1. Van den Bossche J, Bogaert P, van Hengel J, Guerin C, Berx G, Movahedi K, et al. Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes. Blood. 2009;114:4664-74 pubmed publisher
    ..This study identifies the E-cadherin/catenin complex as a discriminative, partly polyamine-regulated feature of IL-4/IL-13-exposed alternatively activated macrophages that contributes to homotypic and heterotypic cellular interactions. ..
  2. Lyssand J, Whiting J, Lee K, Kastl R, Wacker J, Bruchas M, et al. Alpha-dystrobrevin-1 recruits alpha-catulin to the alpha1D-adrenergic receptor/dystrophin-associated protein complex signalosome. Proc Natl Acad Sci U S A. 2010;107:21854-9 pubmed publisher
    ..Taken together, our study implicates ?-catulin as a unique regulator of GPCR signaling and represents a unique expansion of the intricate and continually evolving array of GPCR signaling networks. ..
  3. Oh H, Abraham L, van Hengel J, Stove C, Proszynski T, Gevaert K, et al. Interaction of ?-catulin with dystrobrevin contributes to integrity of dystrophin complex in muscle. J Biol Chem. 2012;287:21717-28 pubmed publisher
    ..elegans and mammalian muscles and strongly suggests that this interaction contributes to the integrity of the dystrophin complex. ..
  4. Stirbat T, Mgharbel A, Bodennec S, Ferri K, Mertani H, Rieu J, et al. Fine tuning of tissues' viscosity and surface tension through contractility suggests a new role for ?-catenin. PLoS ONE. 2013;8:e52554 pubmed publisher
  5. Yao M, Qiu W, Liu R, Efremov A, Cong P, Seddiki R, et al. Force-dependent conformational switch of ?-catenin controls vinculin binding. Nat Commun. 2014;5:4525 pubmed publisher
    ..Our findings demonstrate that physiologically relevant forces reversibly unfurl ?-catenin, activating vinculin binding, which then stabilizes ?-catenin in its open conformation, transforming force into a sustainable biochemical signal...
  6. Acar M, Kocherlakota K, Murphy M, Peyer J, Oguro H, Inra C, et al. Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal. Nature. 2015;526:126-30 pubmed publisher
    ..Here, using a green fluorescent protein (GFP) knock-in for the gene Ctnnal1 in mice (hereafter denoted as α-catulin(GFP)), we discover that α-catulin(GFP) is expressed by only 0...
  7. Xiang Y, Tan Y, Zhang J, Qin X, Hu B, Wang Y, et al. Wound repair and proliferation of bronchial epithelial cells regulated by CTNNAL1. J Cell Biochem. 2008;103:920-30 pubmed
    ..Our previous study indicated that adhesion molecule catenin alpha-like 1 (CTNNAL1) is relevant closely to asthma susceptibility, but its biological function or significance is still unclear...