Gene Symbol: Csde1
Description: cold shock domain containing E1, RNA binding
Alias: AA960392, BC016898, D3Jfr1, mKIAA0885, unr, cold shock domain-containing protein E1, NRAS-related, upstream of NRAS
Pan Y, Zhang L, Liu Q, Li Y, Guo H, Peng Y, et al
. Insertion of a knockout-first cassette in Ampd1 gene leads to neonatal death by disruption of neighboring genes expression. Sci Rep. 2016;6:35970 pubmed publisher
..This study, together with other reports, strongly suggests that removal of targeting cassette by site-specific recombinases is very important for the accurate phenotypic interpretation on mice generated by target mutations. ..
Jeffers M, Paciucci R, Pellicer A. Characterization of unr; a gene closely linked to N-ras. Nucleic Acids Res. 1990;18:4891-9 pubmed
..RNase protection assays reveal that this gene, unr, is transcribed in the same direction as N-ras and that its 3' end is located just 130 base pairs away from the ..
Dormoy Raclet V, Markovits J, Jacquemin Sablon A, Jacquemin Sablon H. Regulation of Unr expression by 5'- and 3'-untranslated regions of its mRNA through modulation of stability and IRES mediated translation. RNA Biol. 2005;2:e27-35 pubmed
b>Unr (upstream of N-ras) is a cytoplasmic RNA-binding protein that can act as a regulator of mRNA stability and IRES-mediated translation...
Elatmani H, Dormoy Raclet V, Dubus P, Dautry F, Chazaud C, Jacquemin Sablon H. The RNA-binding protein Unr prevents mouse embryonic stem cells differentiation toward the primitive endoderm lineage. Stem Cells. 2011;29:1504-16 pubmed publisher
..We report that the cytoplasmic RNA-binding protein Unr prevents the differentiation of ESCs into primitive endoderm (PrE)...
Horos R, Ijspeert H, Pospisilova D, Sendtner R, Andrieu Soler C, Taskesen E, et al
. Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts. Blood. 2012;119:262-72 pubmed publisher
..Among these were Bag1, encoding a Hsp70 cochaperone, and Csde1, encoding an RNA-binding protein, and both were expressed at increased levels in erythroblasts...
Kobayashi H, Kawauchi D, Hashimoto Y, Ogata T, Murakami F. The control of precerebellar neuron migration by RNA-binding protein Csde1. Neuroscience. 2013;253:292-303 pubmed publisher
..As a result, we identified the following three genes through the screening; Calm1, Septin 11, and Csde1. We report here functional analysis of one of these genes, Csde1, an RNA-binding protein implicated in the post-..
López Fernández L, López Alañón D, del Mazo J. Different developmental pattern of N-ras and unr gene expression in mouse gametogenic and somatic tissues. Biochim Biophys Acta. 1995;1263:10-6 pubmed
Accumulation of transcripts from N-ras and unr genes was comparatively analyzed during the development of germline and somatic tissues...
Tinton S, Schepens B, Bruynooghe Y, Beyaert R, Cornelis S. Regulation of the cell-cycle-dependent internal ribosome entry site of the PITSLRE protein kinase: roles of Unr (upstream of N-ras) protein and phosphorylated translation initiation factor eIF-2alpha. Biochem J. 2005;385:155-63 pubmed
..Progressive deletion analysis showed that both a purine-rich sequence and a Unr (upstream of N-ras) consensus binding site are essential for PITSLRE IRES activity...