Gene Symbol: Copb2
Description: coatomer protein complex, subunit beta 2 (beta prime)
Alias: AI256832, coatomer subunit beta', beta'-COP, beta'-coat protein, p102
Species: mouse
Products:     Copb2

Top Publications

  1. Tarsounas M, Heng H, Ye C, Pearlman R, Moens P. Identification of the mouse beta'-COP Golgi component as a spermatocyte autoantigen in scleroderma and mapping of its gene Copb2 to mouse chromosome 9. Cytogenet Cell Genet. 1999;87:201-4 pubmed
    ..FISH analyses assigned the beta'-COP gene Copb2 to mouse Chromosome 9, region E3-F1...
  2. Shi F, Ding S, Zhao S, Han M, Zhuang Y, Xu T, et al. A piggyBac insertion disrupts Foxl2 expression that mimics BPES syndrome in mice. Hum Mol Genet. 2014;23:3792-800 pubmed publisher
    ..Therefore, this mutant presents an excellent animal model for mechanistic study of BPES and regulation of Foxl2. ..
  3. Hosaka M, Toda K, Takatsu H, Torii S, Murakami K, Nakayama K. Structure and intracellular localization of mouse ADP-ribosylation factors type 1 to type 6 (ARF1-ARF6). J Biochem. 1996;120:813-9 pubmed
    ..These results suggest that although all the ARF proteins play fundamental and critical roles in cellular function, they are involved in different vesicular transport processes. ..
  4. Loh E, Peter F, Subramaniam V, Hong W. Mammalian Bet3 functions as a cytosolic factor participating in transport from the ER to the Golgi apparatus. J Cell Sci. 2005;118:1209-22 pubmed
    ..Gel filtration analysis demonstrates that Bet3 exists in two distinct pools in the cytosol, the high-molecular-weight pool may represent the TRAPP complex, whereas the other probably represents the monomeric Bet3. ..
  5. Distasio A, Driver A, Sund K, Donlin M, Muraleedharan R, Pooya S, et al. Copb2 is essential for embryogenesis and hypomorphic mutations cause human microcephaly. Hum Mol Genet. 2017;26:4836-4848 pubmed publisher an amino acid substitution in a WD40 domain of the highly conserved Coatomer Protein Complex, Subunit Beta 2 (COPB2)...