Cnrip1

Summary

Gene Symbol: Cnrip1
Description: cannabinoid receptor interacting protein 1
Alias: 1500041B16Rik, 3110054C06Rik, 5330437A18Rik, AI854501, C2orf32, CB1 cannabinoid receptor-interacting protein 1, CRIP-1
Species: mouse
Products:     Cnrip1

Top Publications

  1. Keimpema E, Barabas K, Morozov Y, Tortoriello G, Torii M, Cameron G, et al. Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding. J Neurosci. 2010;30:13992-4007 pubmed publisher
  2. Blume L, Eldeeb K, Bass C, Selley D, Howlett A. Cannabinoid receptor interacting protein (CRIP1a) attenuates CB1R signaling in neuronal cells. Cell Signal. 2015;27:716-726 pubmed publisher
  3. Smith T, Blume L, Straiker A, Cox J, David B, McVoy J, et al. Cannabinoid receptor-interacting protein 1a modulates CB1 receptor signaling and regulation. Mol Pharmacol. 2015;87:747-65 pubmed publisher
    ..Thus, CRIP1a appears to act as a broad negative regulator of CB1R function. ..
  4. Guggenhuber S, Alpar A, Chen R, Schmitz N, Wickert M, Mattheus T, et al. Cannabinoid receptor-interacting protein Crip1a modulates CB1 receptor signaling in mouse hippocampus. Brain Struct Funct. 2016;221:2061-74 pubmed publisher
    ..Collectively, our data indicate that CRIP1a enhances hippocampal CB1R signaling in vivo. ..
  5. Blume L, Leone Kabler S, Luessen D, Marrs G, Lyons E, Bass C, et al. Cannabinoid receptor interacting protein suppresses agonist-driven CB1 receptor internalization and regulates receptor replenishment in an agonist-biased manner. J Neurochem. 2016;139:396-407 pubmed publisher