Gene Symbol: Cmtm2a
Description: CKLF-like MARVEL transmembrane domain containing 2A
Alias: 1700001K04Rik, 1700041N15Rik, 1700063K20Rik, AI449770, ARR19, C32, CKLF3, CKLF4, CKLF5, Cklf, Cklf1, Cklfsf2-1b, Cklfsf2a, UCK-1, CKLF-like MARVEL transmembrane domain-containing protein 2A, chemokine-like factor super family 2A, chemokine-like factor superfamily 2-1b, chemokine-like factor superfamily member 2A
Species: mouse
Products:     Cmtm2a

Top Publications

  1. Jeong B, Hong C, Chattopadhyay S, Park J, Gong E, Kim H, et al. Androgen receptor corepressor-19 kDa (ARR19), a leucine-rich protein that represses the transcriptional activity of androgen receptor through recruitment of histone deacetylase. Mol Endocrinol. 2004;18:13-25 pubmed
    ..Here, we report a novel AR corepressor ARR19 (androgen receptor corepressor-19 kDa), which has been isolated as a putative androgen-induced gene from murine ..
  2. Qamar I, Park E, Gong E, Lee H, Lee K. ARR19 (androgen receptor corepressor of 19 kDa), an antisteroidogenic factor, is regulated by GATA-1 in testicular Leydig cells. J Biol Chem. 2009;284:18021-32 pubmed publisher
    b>ARR19 (androgen receptor corepressor of 19 kDa), which encodes for a leucine-rich protein, is expressed abundantly in the testis...
  3. Li T, Han W, Yang T, Ding P, Rui M, Liu D, et al. Molecular cloning and identification of mouse Cklfsf2a and Cklfsf2b, two homologues of human CKLFSF2. Int J Biochem Cell Biol. 2006;38:420-9 pubmed
    ..For further study, we cloned the two mouse genes by EST assembly and RT-PCR methods and designated them as mouse Cklfsf2a and Cklfsf2b...
  4. Qamar I, Gong E, Kim Y, Song C, Lee H, Chun S, et al. Anti-steroidogenic factor ARR19 inhibits testicular steroidogenesis through the suppression of Nur77 transactivation. J Biol Chem. 2010;285:22360-9 pubmed publisher
    b>ARR19 (androgen receptor corepressor-19 kDa), a leucine-rich protein whose expression is down-regulated by luteinizing hormone and cAMP, is differentially expressed during the development of Leydig cells and inhibits testicular ..
  5. Wang Z, Zhang Y, Yuan Y, Chen N. Developmental expression of chemokine-like factor 1, a novel member of chemokines family, in postnatal rat cerebral cortex. Neurosci Lett. 2012;519:51-5 pubmed publisher
    Chemokine-like factor 1 (CKLF1) has been implicated to induce the migration of neuroblastoma cells and is abundant in fetal brain but scarce in adult brain...
  6. Xia D, Li X, Lou Y, Han W, Ding P, Zhang Y, et al. Overexpression of chemokine-like factor 2 promotes the proliferation and survival of C2C12 skeletal muscle cells. Biochim Biophys Acta. 2002;1591:163-173 pubmed
    Chemokine-like factor 1 (CKLF1) is a novel cytokine first cloned from U937 cells...
  7. Han W, Ding P, Xu M, Wang L, Rui M, Shi S, et al. Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation. Genomics. 2003;81:609-17 pubmed
    TM4SF11 is only 102 kb from the chemokine gene cluster composed of SCYA22, SCYD1, and SCYA17 on chromosome 16q13. CKLF maps on chromosome 16q22...
  8. Rui M, Xia D, Zhang Y, Han W, Wang L, Ding P, et al. Molecular cloning and characterization of four isoforms of mCKLF, mouse homologues of human chemokine-like factor. Mol Biol Rep. 2003;30:229-37 pubmed
    Chemokine-like factor1 (CKLF1), and its three isoforms (CKLF2, 3 and 4), are recently identified human cytokines...
  9. Qamar I, Ahmad M, Narayanasamy A. A time-course study of long term over-expression of ARR19 in mice. Sci Rep. 2015;5:13014 pubmed publisher
    A leucine-rich protein, ARR19 (androgen receptor corepressor-19 kDa), is highly expressed in male reproductive organs and moderately in others...