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Genomes and Genes | Cd97SummaryGene Symbol: Cd97 Description: CD97 antigen Alias: AA409984, TM7LN1, EGF-TM7 receptor Species: mouse Top Publications
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Publications
CD97 is differentially expressed on murine hematopoietic stem-and progenitor-cellsMelissa van Pel
Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
Haematologica 93:1137-44. 2008b>CD97 is a member of the epidermal growth factor-seven transmembrane (EGF-TM7) family of adhesion receptors and is broadly expressed on hematopoietic cells...
The epidermal growth factor-seven transmembrane (EGF-TM7) receptor CD97 is required for neutrophil migration and host defenseJaklien C Leemans
Laboratory for Experimental Internal Medicine, Department of Pathology, Academic Medical Center, University of Amsterdam, 1100 DE Amsterdam, The Netherlands
J Immunol 172:1125-31. 2004..Family members CD97, EGF module-containing mucin-like receptor (EMR) 1, EMR2, EMR3, EMR4, and EGF-TM7-latrophilin-related protein are ..
Structural characterization of mouse CD97 and study of its specific interaction with the murine decay-accelerating factor (DAF, CD55)Y M Qian
Center for Experimental Therapeutics and Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Immunology 98:303-11. 1999b>CD97 is a newly identified, activation-associated human leucocyte antigen with seven putative transmembrane domains...- Deletion of either CD55 or CD97 ameliorates arthritis in mouse modelsRobert M Hoek
Academic Medical Center, Amsterdam, The Netherlands
Arthritis Rheum 62:1036-42. 2010..abundantly present on fibroblast-like synoviocytes and is also a ligand of the adhesion-class heptahelical receptor CD97, which is expressed by infiltrating macrophages... - Molecular cloning and characterization of mouse CD97J Hamann
Department of Immunobiology, CLB and Laboratory for Experimental and Clinical Immunology, Academic Medical Centre, University of Amsterdam, Plesmanlaan 125, 1066 CX Amsterdam, The Netherlands
Int Immunol 12:439-48. 2000The EGF-TM7 family (CD97 and EMR1) is a group of class II seven-span transmembrane receptors predominantly expressed by cells of the immune system... - Analysis of CD97 expression and manipulation: antibody treatment but not gene targeting curtails granulocyte migrationHenrike Veninga
Department of Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
J Immunol 181:6574-83. 2008The heptahelical receptor CD97 is a defining member of the EGF-TM7 family of adhesion class receptors... - Improved antibacterial host defense and altered peripheral granulocyte homeostasis in mice lacking the adhesion class G protein receptor CD97Tao Wang
Cell and Cancer Biology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Infect Immun 75:1144-53. 2007b>CD97 is a member of the adhesion family of G protein-coupled receptors. Alternatively spliced forms of CD97 bind integrins alpha5beta1 and alphavbeta3, decay accelerating factor, or dermatan sulfate... - The EGF-TM7 family: a postgenomic viewMark J Kwakkenbos
Laboratory for Experimental Immunology, Academic Medical Center, University of Amsterdam, G1 106, PO Box 22700, 1100 DE, Amsterdam, The Netherlands
Immunogenetics 55:655-66. 2004..Recent in vivo studies demonstrate a role of the EGF-TM7 receptor CD97 in leukocyte migration... - Physical mapping of EMR1 and CD97 in human Chromosome 19 and assignment of Cd97 to mouse Chromosome 8 suggest an ancient genomic duplicationE A Carver
Biology and Biotechnology Research Program, Lawrence Livermore National Laboratory, P.O. Box 808, L-452, Livermore, California 94550, USA
Mamm Genome 10:1039-40. 1999 - Overexpression of CD97 in intestinal epithelial cells of transgenic mice attenuates colitis by strengthening adherens junctionsSusann Becker
Research Laboratories, Department of Surgery, University of Leipzig, Leipzig, Germany
PLoS ONE 5:e8507. 2010The adhesion G-protein-coupled receptor CD97 is present in normal colonic enterocytes but overexpressed in colorectal carcinoma... - Therapeutic antibody targeting of CD97 in experimental arthritis: the role of antigen expression, shedding, and internalization on the pharmacokinetics of anti-CD97 monoclonal antibody 1B2Dorien M de Groot
Schering Plough Research Institute, Oss, The Netherlands
J Immunol 183:4127-34. 2009b>CD97 is a member of the EGF-TM7 family of adhesion class receptors, with a proposed role in inflammatory cell recruitment... - Differential role of CD97 in interleukin-8-induced and granulocyte-colony stimulating factor-induced hematopoietic stem and progenitor cell mobilizationMelissa van Pel
Department of Immunohematology and Bloodtransfusion, Leiden University Medical Center, E3 Q, P O Box 9600, 2300 RC Leiden, The Netherlands
Haematologica 93:601-4. 2008b>CD97 is broadly expressed on hematopoietic cells and is involved in neutrophil migration... - A novel role for CD55 in granulocyte homeostasis and anti-bacterial host defenseHenrike Veninga
Department of Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
PLoS ONE 6:e24431. 2011In addition to its complement-regulating activity, CD55 is a ligand of the adhesion class G protein-coupled receptor CD97; however, the relevance of this interaction has remained elusive...