carbonic anhydrase VII

Summary

Gene Symbol: carbonic anhydrase VII
Description: carbonic anhydrase 7
Alias: AV343731, Ca7, carbonic anhydrase 7, CA-VII, carbonate dehydratase VII, carbonic anhydrase VII
Species: mouse
Products:     carbonic anhydrase VII

Top Publications

  1. Earnhardt J, Qian M, Tu C, Lakkis M, Bergenhem N, Laipis P, et al. The catalytic properties of murine carbonic anhydrase VII. Biochemistry. 1998;37:10837-45 pubmed
    b>Carbonic anhydrase VII (CA VII) appears to be the most highly conserved of the active mammalian carbonic anhydrases. We have characterized the catalytic activity and inhibition properties of a recombinant murine CA VII...
  2. Selbert S, Fischer P, Menke A, Jockusch H, Pongratz D, Noegel A. Annexin VII relocalization as a result of dystrophin deficiency. Exp Cell Res. 1996;222:199-208 pubmed
    ..The potential of annexin VII to serve as a tool with which cellular Ca2+ levels can be studied and different muscular disorders classified is discussed. ..
  3. Lakkis M, Bergenhem N, Tashian R. Expression of mouse carbonic anhydrase VII in E. coli and demonstration of its CO2 hydrase activity. Biochem Biophys Res Commun. 1996;226:268-72 pubmed
    ..Although the gene for human CA VII has been cloned and characterized, the corresponding protein has not previously been purified, and hence, the CO2 ..
  4. Pan P, Rodriguez A, Parkkila S. A systematic quantification of carbonic anhydrase transcripts in the mouse digestive system. BMC Mol Biol. 2007;8:22 pubmed
    ..It contributes to a deeper understanding of the distribution of CA isozymes and their potential roles in the mouse digestive system. ..
  5. Pan P, Waheed A, Sly W, Parkkila S. Carbonic anhydrases in the mouse harderian gland. J Mol Histol. 2010;41:411-7 pubmed publisher
    ..The high expression of mitochondrial CAVB at both mRNA and protein levels suggests a role in lipid synthesis, a key physiological process of the harderian gland. ..
  6. Wu L, Sagong B, Choi J, Kim U, Bok J. A systematic survey of carbonic anhydrase mRNA expression during mammalian inner ear development. Dev Dyn. 2013;242:269-80 pubmed publisher
    ..The temporal and spatial expression patterns of each CA isozyme suggest unique and differential roles in inner ear development and function. ..
  7. Ruusuvuori E, Huebner A, Kirilkin I, Yukin A, Blaesse P, Helmy M, et al. Neuronal carbonic anhydrase VII provides GABAergic excitatory drive to exacerbate febrile seizures. EMBO J. 2013;32:2275-86 pubmed publisher
    Brain carbonic anhydrases (CAs) are known to modulate neuronal signalling. Using a novel CA VII (Car7) knockout (KO) mouse as well as a CA II (Car2) KO and a CA II/VII double KO, we show that mature hippocampal pyramidal neurons are ..

Detail Information

Publications7

  1. Earnhardt J, Qian M, Tu C, Lakkis M, Bergenhem N, Laipis P, et al. The catalytic properties of murine carbonic anhydrase VII. Biochemistry. 1998;37:10837-45 pubmed
    b>Carbonic anhydrase VII (CA VII) appears to be the most highly conserved of the active mammalian carbonic anhydrases. We have characterized the catalytic activity and inhibition properties of a recombinant murine CA VII...
  2. Selbert S, Fischer P, Menke A, Jockusch H, Pongratz D, Noegel A. Annexin VII relocalization as a result of dystrophin deficiency. Exp Cell Res. 1996;222:199-208 pubmed
    ..The potential of annexin VII to serve as a tool with which cellular Ca2+ levels can be studied and different muscular disorders classified is discussed. ..
  3. Lakkis M, Bergenhem N, Tashian R. Expression of mouse carbonic anhydrase VII in E. coli and demonstration of its CO2 hydrase activity. Biochem Biophys Res Commun. 1996;226:268-72 pubmed
    ..Although the gene for human CA VII has been cloned and characterized, the corresponding protein has not previously been purified, and hence, the CO2 ..
  4. Pan P, Rodriguez A, Parkkila S. A systematic quantification of carbonic anhydrase transcripts in the mouse digestive system. BMC Mol Biol. 2007;8:22 pubmed
    ..It contributes to a deeper understanding of the distribution of CA isozymes and their potential roles in the mouse digestive system. ..
  5. Pan P, Waheed A, Sly W, Parkkila S. Carbonic anhydrases in the mouse harderian gland. J Mol Histol. 2010;41:411-7 pubmed publisher
    ..The high expression of mitochondrial CAVB at both mRNA and protein levels suggests a role in lipid synthesis, a key physiological process of the harderian gland. ..
  6. Wu L, Sagong B, Choi J, Kim U, Bok J. A systematic survey of carbonic anhydrase mRNA expression during mammalian inner ear development. Dev Dyn. 2013;242:269-80 pubmed publisher
    ..The temporal and spatial expression patterns of each CA isozyme suggest unique and differential roles in inner ear development and function. ..
  7. Ruusuvuori E, Huebner A, Kirilkin I, Yukin A, Blaesse P, Helmy M, et al. Neuronal carbonic anhydrase VII provides GABAergic excitatory drive to exacerbate febrile seizures. EMBO J. 2013;32:2275-86 pubmed publisher
    Brain carbonic anhydrases (CAs) are known to modulate neuronal signalling. Using a novel CA VII (Car7) knockout (KO) mouse as well as a CA II (Car2) KO and a CA II/VII double KO, we show that mature hippocampal pyramidal neurons are ..