Gene Symbol: C1ra
Description: complement component 1, r subcomponent A
Alias: AI132558, C1r, mC1rA, complement C1r-A subcomponent, complement component 1 subcomponent r-A, complement component 1, r-A subcomponent
Species: mouse
Products:     C1ra

Top Publications

  1. Garnier G, Circolo A, Xu Y, Volanakis J. Complement C1r and C1s genes are duplicated in the mouse: differential expression generates alternative isomorphs in the liver and in the male reproductive system. Biochem J. 2003;371:631-40 pubmed
    ..One set of these genes, referred to as c1rA and c1sA, are primarily expressed in the liver and are therefore the homologues of the human C1r and C1s genes...
  2. Byun S, Jeon I, Lee H, Kim T. IFN-gamma upregulates expression of the mouse complement C1rA gene in keratinocytes via IFN-regulatory factor-1. J Invest Dermatol. 2007;127:1187-96 pubmed
    We examined the expression of the mouse complement component C1rA (mC1rA) in IFN-gamma-stimulated mouse keratinocytes (Pam 212) and found that it was upregulated...
  3. Lawson P, Reid K. A novel PCR-based technique using expressed sequence tags and gene homology for murine genetic mapping: localization of the complement genes. Int Immunol. 2000;12:231-40 pubmed
    ..It was shown that the C3a receptor C1r and C1s genes form an unexpected complement gene cluster towards the telomeric end of chromosome 6...
  4. Byun S, Bahk Y, Ryoo Z, Kim K, Hwang H, Lee J, et al. Identification of cDNA encoding a serine protease homologous to human complement C1r precursor from grafted mouse skin. J Invest Dermatol. 2001;116:374-9 pubmed
    We isolated a cDNA clone from grafted mouse skin that encodes a serine protease homologous to human C1r. The C1r protease is involved in the activation of the first component of the classical pathway in the complement system...