Art1

Summary

Gene Symbol: Art1
Description: ADP-ribosyltransferase 1
Alias: ADPRT, ARTC1, Yac-1, ADP-ribosyltransferase C2 and C3 toxin-like 1, GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1, mono(ADP-ribosyl)transferase 1
Species: mouse

Top Publications

  1. ncbi Cloning and characterization of a novel membrane-associated lymphocyte NAD:arginine ADP-ribosyltransferase
    I J Okazaki
    Pulmonary Critical Care Medicine Branch, NHLBI, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 271:22052-7. 1996
  2. ncbi Molecular characterization of a glycosylphosphatidylinositol-linked ADP-ribosyltransferase from lymphocytes
    I J Okazaki
    Pulmonary Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1434, USA
    Blood 88:915-21. 1996
  3. ncbi Assignment of the human and mouse genes for muscle ecto mono (ADPribosyl)transferase to a conserved linkage group on human chromosome 11p15 and mouse chromosome 7
    F Koch-Nolte
    Department of Immunology, University Hospital, Hamburg, 20246, Federal Republic of Germany
    Genomics 36:215-6. 1996
  4. ncbi Prostate cancer progression, metastasis, and gene expression in transgenic mice
    C Perez-stable
    Veterans Affairs Medical Center, and Department of Medicine, University of Miami School of Medicine, Florida 33101, USA
    Cancer Res 57:900-6. 1997
  5. ncbi Molecular cloning of a functional murine arginine-specific mono-ADP-ribosyltransferase and its expression in lymphoid cells
    Y Yu
    Department of Molecular Microbiology and Immunology, USC Norris Comprehensive Cancer Center, University of Southern California School of Medicine, Los Angeles 90033, USA
    DNA Cell Biol 16:235-44. 1997
  6. ncbi Molecular characterization and expression of the gene for mouse NAD+:arginine ecto-mono(ADP-ribosyl)transferase, Art1
    R Braren
    Institute for Immunology, University Hospital, Martinistr 52, D 20246 Hamburg, Germany
    Biochem J 336:561-8. 1998
  7. ncbi Structure, chromosomal localization, and expression of the gene for mouse ecto-mono(ADP-ribosyl)transferase ART5
    G Glowacki
    Institute for Immunology, University Hospital, Martinistrasse 52, 20246 Hamburg, Germany
    Gene 275:267-77. 2001
  8. ncbi The family of toxin-related ecto-ADP-ribosyltransferases in humans and the mouse
    Gustavo Glowacki
    Institute of Immunology, University Hospital, Martinistrasse 52, D 20246 Hamburg, Germany
    Protein Sci 11:1657-70. 2002
  9. ncbi Identification of regulatory domains in ADP-ribosyltransferase-1 that determine transferase and NAD glycohydrolase activities
    Christelle Bourgeois
    Pulmonary Critical Care Medicine Branch, NHLBI, National Institutes of Health, Bethesda, Maryland 20892 1590, USA
    J Biol Chem 278:26351-5. 2003

Scientific Experts

  • F Koch-Nolte
  • G Glowacki
  • R Braren
  • Christelle Bourgeois
  • F Haag
  • Gustavo Glowacki
  • I J Okazaki
  • M Cetkovic-Cvrlje
  • E H Leiter
  • Y Yu
  • C Perez-stable
  • Ian Okazaki
  • Joel Moss
  • Maria Nightingale
  • Eleanor Cavanaugh
  • Fernando Bazan
  • Rickmer Braren
  • Friedrich Haag
  • Maren Kühl
  • J Moss
  • Marion Nissen
  • Marina Cetkovic-Cvrlje
  • H J Kim
  • Friedrich Koch-Nolte
  • Pedro Reche
  • Edward Leiter
  • Kathrin Firner
  • M Nissen
  • S Okamoto
  • B A Roos
  • L J Deftos
  • E Nemoto
  • G Dennert
  • N H Altman
  • P P Mehta
  • H G Thiele
  • N G McElvaney
  • E Lesma

Detail Information

Publications9

  1. ncbi Cloning and characterization of a novel membrane-associated lymphocyte NAD:arginine ADP-ribosyltransferase
    I J Okazaki
    Pulmonary Critical Care Medicine Branch, NHLBI, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 271:22052-7. 1996
    ....
  2. ncbi Molecular characterization of a glycosylphosphatidylinositol-linked ADP-ribosyltransferase from lymphocytes
    I J Okazaki
    Pulmonary Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1434, USA
    Blood 88:915-21. 1996
    ..Thus, we have cloned a novel gene that has properties identical to the transferase detected in CTL, and may be involved in the NAD-dependent regulation of proliferation and cytotoxicity...
  3. ncbi Assignment of the human and mouse genes for muscle ecto mono (ADPribosyl)transferase to a conserved linkage group on human chromosome 11p15 and mouse chromosome 7
    F Koch-Nolte
    Department of Immunology, University Hospital, Hamburg, 20246, Federal Republic of Germany
    Genomics 36:215-6. 1996
  4. ncbi Prostate cancer progression, metastasis, and gene expression in transgenic mice
    C Perez-stable
    Veterans Affairs Medical Center, and Department of Medicine, University of Miami School of Medicine, Florida 33101, USA
    Cancer Res 57:900-6. 1997
    ..We propose the Ggamma/T-15 transgenic line as a model of highly aggressive androgen-independent metastatic prostate carcinoma with features similar to end-stage prostate cancer in humans...
  5. ncbi Molecular cloning of a functional murine arginine-specific mono-ADP-ribosyltransferase and its expression in lymphoid cells
    Y Yu
    Department of Molecular Microbiology and Immunology, USC Norris Comprehensive Cancer Center, University of Southern California School of Medicine, Los Angeles 90033, USA
    DNA Cell Biol 16:235-44. 1997
    A protein mono-ADP-ribosyltransferase (ADPRT), anchored in the cell membrane as a glycosylphosphatidylinositol (GPI)-anchored cell-surface enzyme, was recently described on murine cytotoxic T cells (CTL)...
  6. ncbi Molecular characterization and expression of the gene for mouse NAD+:arginine ecto-mono(ADP-ribosyl)transferase, Art1
    R Braren
    Institute for Immunology, University Hospital, Martinistr 52, D 20246 Hamburg, Germany
    Biochem J 336:561-8. 1998
    ..We have characterized the gene for mouse arginine-specific ADP-ribosyltransferase, Art1. Southern blot analyses indicate that Art1 is a single-copy gene...
  7. ncbi Structure, chromosomal localization, and expression of the gene for mouse ecto-mono(ADP-ribosyl)transferase ART5
    G Glowacki
    Institute for Immunology, University Hospital, Martinistrasse 52, 20246 Hamburg, Germany
    Gene 275:267-77. 2001
    ..6 cM in close proximity to the Art1, Art2a and Art2b genes...
  8. ncbi The family of toxin-related ecto-ADP-ribosyltransferases in humans and the mouse
    Gustavo Glowacki
    Institute of Immunology, University Hospital, Martinistrasse 52, D 20246 Hamburg, Germany
    Protein Sci 11:1657-70. 2002
    ..This suggests that the two enzyme families that catalyze reversible mono-ADP-ribosylation either were lost from the genomes of these nonchordata eucaryotes or were subject to horizontal gene transfer between kingdoms...
  9. ncbi Identification of regulatory domains in ADP-ribosyltransferase-1 that determine transferase and NAD glycohydrolase activities
    Christelle Bourgeois
    Pulmonary Critical Care Medicine Branch, NHLBI, National Institutes of Health, Bethesda, Maryland 20892 1590, USA
    J Biol Chem 278:26351-5. 2003
    Mono-ADP-ribosyltransferases (ART1-7) transfer ADP-ribose from NAD+ to proteins (transferase activity) or water (NAD glycohydrolase activity)...