Gene Symbol: Arp1
Description: ARP1 actin-related protein 1A, centractin alpha
Alias: Arp1, alpha-Arp1, alpha-centractin, ARP1 actin-related protein 1 homolog A, centractin alpha, Arp1 centractin alpha, Arp1 contractin alpha, actin-RPV, actin-related protein 1 alpha, actin-related protein 1 homolog A, centractin, centrosome-associated actin homolog
Species: mouse
Products:     Arp1

Top Publications

  1. Yogo K, Mizutamari M, Mishima K, Takenouchi H, Ishida Kitagawa N, Sasaki T, et al. Src homology 2 (SH2)-containing 5'-inositol phosphatase localizes to podosomes, and the SH2 domain is implicated in the attenuation of bone resorption in osteoclasts. Endocrinology. 2006;147:3307-17 pubmed
    ..These results demonstrate that c-Src enhances the translocation of SHIP to podosomes and regulates its function there through the SH2 domain, leading to an attenuation of bone resorption. ..
  2. Kusano K, Abe H, Obinata T. Primary structure of mouse actin-related protein 1 (Arp1) and its tissue expression. Zoolog Sci. 1997;14:77-82 pubmed
    ..1996). Among them, Arp1 exhibits the highest homology with conventional actin...
  3. Eckley D, Schroer T. Interactions between the evolutionarily conserved, actin-related protein, Arp11, actin, and Arp1. Mol Biol Cell. 2003;14:2645-54 pubmed
    ..The cargo-binding domain contains a short, actin-like filament of the actin-related protein Arp1, a second actin-related protein, Arp11, and conventional actin...
  4. Lin S, Bassik M, Suh H, Nishino M, Arroyo J, Hahn W, et al. PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulum. J Biol Chem. 2006;281:23003-12 pubmed
    ..These studies support the hypothesis that PP2A-mediated dephosphorylation of BCL-2 is required to protect BCL-2 from proteasome-dependent degradation, affecting resistance to ER stress. ..
  5. Clarkson Y, Gillespie T, Perkins E, Lyndon A, Jackson M. Beta-III spectrin mutation L253P associated with spinocerebellar ataxia type 5 interferes with binding to Arp1 and protein trafficking from the Golgi. Hum Mol Genet. 2010;19:3634-41 pubmed publisher
    ..Interaction of beta-III spectrin with Arp1, a subunit of the dynactin-dynein complex, is also lost with the L253P substitution...