Gene Symbol: Akap11
Description: A kinase (PRKA) anchor protein 11
Alias: 6330501D17Rik, AKAP220, Gm80, PRKA11, mKIAA0629, A-kinase anchor protein 11
Species: mouse
Products:     Akap11

Top Publications

  1. Logue J, Whiting J, Tunquist B, Langeberg L, Scott J. Anchored protein kinase A recruitment of active Rac GTPase. J Biol Chem. 2011;286:22113-21 pubmed publisher
    ..In this report we describe the identification and characterization of a ternary complex of AKAP220, the PKA holoenzyme, and the IQ domain GTPase-activating protein 2 isoform (IQGAP2) that is enriched at cortical ..
  2. Day M, Gaietta G, Sastri M, Koller A, Mackey M, Scott J, et al. Isoform-specific targeting of PKA to multivesicular bodies. J Cell Biol. 2011;193:347-63 pubmed publisher
    ..This localization depends on binding to AKAP11, which binds tightly to free RI? or RI? in complex with catalytic subunit (holoenzyme)...
  3. Whiting J, Ogier L, Forbush K, Bucko P, Gopalan J, Seternes O, et al. AKAP220 manages apical actin networks that coordinate aquaporin-2 location and renal water reabsorption. Proc Natl Acad Sci U S A. 2016;113:E4328-37 pubmed publisher
    ..facets of this homeostatic mechanism are under the control of A-Kinase Anchoring Protein 220 (AKAP220; product of the Akap11 gene)...