Agl

Summary

Gene Symbol: Agl
Description: amylo-1,6-glucosidase, 4-alpha-glucanotransferase
Alias: 1110061O17Rik, 9430004C13Rik, 9630046L06Rik, AI850929, C77197, glycogen debranching enzyme
Species: mouse
Products:     Agl

Top Publications

  1. Sakoda H, Fujishiro M, Fujio J, Shojima N, Ogihara T, Kushiyama A, et al. Glycogen debranching enzyme association with beta-subunit regulates AMP-activated protein kinase activity. Am J Physiol Endocrinol Metab. 2005;289:E474-81 pubmed
    ..Mass spectrometry and a Mascot search revealed this protein to be a glycogen debranching enzyme (GDE)...
  2. Cheng A, Zhang M, Gentry M, Worby C, Dixon J, Saltiel A. A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease. Genes Dev. 2007;21:2399-409 pubmed
    Cori's disease is a glycogen storage disorder characterized by a deficiency in the glycogen debranching enzyme, amylo-1,6-glucosidase,4-alpha-glucanotransferase (AGL)...
  3. Schliselfeld L, Danon M. Inverse relationship of skeletal muscle glycogen from wild-type and genetically modified mice to their phosphorylase a activity. Biochem Biophys Res Commun. 2002;290:874-7 pubmed
    ..00 mM AMP (4.8% and less glycogen phosphorylase a). This suggests that there is an inverse relationship between mouse muscle phosphorylase a and the muscle's glycogen content. ..
  4. Probert F, Rice P, Scudamore C, Wells S, Williams R, Hough T, et al. ¹H NMR metabolic profiling of plasma reveals additional phenotypes in knockout mouse models. J Proteome Res. 2015;14:2036-45 pubmed publisher
    ..Significant differences were observed in two KO lines, Agl (MGI: 1924809) and Bbs5 (MGI: 1919819), by (1)H NMR spectroscopy, clinical chemistry, and histopathology...
  5. Liu S, Li Y, Chen Y, Chiang E, Li A, Lee Y, et al. Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in the liver. Hepatology. 2007;46:1413-25 pubmed
  6. Liu K, Wu J, Chen Y. Mouse model of glycogen storage disease type III. Mol Genet Metab. 2014;111:467-76 pubmed publisher
    Glycogen storage disease type IIIa (GSD IIIa) is caused by a deficiency of the glycogen debranching enzyme (GDE), which is encoded by the Agl gene...
  7. Pagliarani S, Lucchiari S, Ulzi G, Violano R, Ripolone M, Bordoni A, et al. Glycogen storage disease type III: A novel Agl knockout mouse model. Biochim Biophys Acta. 2014;1842:2318-28 pubmed publisher
    Glycogen storage disease type III is an autosomal recessive disease characterized by a deficiency in the glycogen debranching enzyme, encoded by AGL...