mltF

Summary

Gene Symbol: mltF
Description: membrane-bound lytic transglycosylase F, murein hydrolase
Alias: ECK2556, JW2542, yfhD
Species:

Top Publications

  1. ncbi Analysis of an Escherichia coli mutant strain resistant to the cell-killing function encoded by the gef gene family
    L K Poulsen
    Biotechnological Institute, Technical University of Denmark, Lyngby
    Mol Microbiol 6:895-905. 1992
  2. ncbi Formylglycinamide ribonucleotide synthetase from Escherichia coli: cloning, sequencing, overproduction, isolation, and characterization
    F J Schendel
    Department of Chemistry, Massachusetts Institute of Technology, Cambridge 02139
    Biochemistry 28:2459-71. 1989
  3. ncbi A conserved domain in putative bacterial and bacteriophage transglycosylases
    E V Koonin
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894
    Trends Biochem Sci 19:106-7. 1994
  4. ncbi Defining a rob regulon in Escherichia coli by using transposon mutagenesis
    M H Bennik
    Department of Cancer Cell Biology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Bacteriol 182:3794-801. 2000
  5. ncbi The C-terminal domain of Escherichia coli YfhD functions as a lytic transglycosylase
    Edie M Scheurwater
    Department of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada
    J Biol Chem 283:8363-73. 2008
  6. ncbi Purification, crystallization and preliminary X-ray diffraction analysis of the lytic transglycosylase MltF from Escherichia coli
    Pramod K Madoori
    Department of Biophysical Chemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands
    Acta Crystallogr Sect F Struct Biol Cryst Commun 66:534-8. 2010

Scientific Experts

  • M H Bennik
  • Pramod K Madoori
  • Edie M Scheurwater
  • Andy Mark W H Thunnissen
  • Anthony J Clarke
  • E V Koonin
  • K E Rudd
  • L K Poulsen
  • F J Schendel
  • N W Larsen
  • S Molin
  • P Andersson
  • E Mueller
  • J Stubbe
  • J M Smith
  • A Shiau

Detail Information

Publications6

  1. ncbi Analysis of an Escherichia coli mutant strain resistant to the cell-killing function encoded by the gef gene family
    L K Poulsen
    Biotechnological Institute, Technical University of Denmark, Lyngby
    Mol Microbiol 6:895-905. 1992
    ..1 kDa. ORF178 and an upstream frame, ORF190, probably constitute an operon...
  2. ncbi Formylglycinamide ribonucleotide synthetase from Escherichia coli: cloning, sequencing, overproduction, isolation, and characterization
    F J Schendel
    Department of Chemistry, Massachusetts Institute of Technology, Cambridge 02139
    Biochemistry 28:2459-71. 1989
    ..Incubation of [18O]FGAR with enzyme, ATP, and glutamine results in quantitative transfer of the 18O to Pi...
  3. ncbi A conserved domain in putative bacterial and bacteriophage transglycosylases
    E V Koonin
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894
    Trends Biochem Sci 19:106-7. 1994
  4. ncbi Defining a rob regulon in Escherichia coli by using transposon mutagenesis
    M H Bennik
    Department of Cancer Cell Biology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Bacteriol 182:3794-801. 2000
    ..activated by normal expression of Rob from the chromosomal rob gene (inaA, marR, aslB, ybaO, mdlA, yfhD, and ybiS). One gene, galT, was repressed by Rob...
  5. ncbi The C-terminal domain of Escherichia coli YfhD functions as a lytic transglycosylase
    Edie M Scheurwater
    Department of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada
    J Biol Chem 283:8363-73. 2008
    ..Based on these data, the enzyme was renamed membrane-bound lytic transglycosylase F. The modular structure of MltF was investigated through genetic engineering for the separate production of identified N-terminal and C-terminal ..
  6. ncbi Purification, crystallization and preliminary X-ray diffraction analysis of the lytic transglycosylase MltF from Escherichia coli
    Pramod K Madoori
    Department of Biophysical Chemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands
    Acta Crystallogr Sect F Struct Biol Cryst Commun 66:534-8. 2010
    The lytic transglycosylase MltF from Escherichia coli is an outer-membrane-bound periplasmic protein with two domains: a C-terminal catalytic domain with a lysozyme-like fold and an N-terminal domain of unknown function that is homologous ..