Gene Symbol: MTH_RS00960
Description: exodeoxyribonuclease III
Alias: MTH212
Species: Methanothermobacter thermautotrophicus str. Delta H

Top Publications

  1. Pfeifer S, Greiner Stöffele T. A recombinant exonuclease III homologue of the thermophilic archaeon Methanothermobacter thermautotrophicus. DNA Repair (Amst). 2005;4:433-44 pubmed
    ..Considering the high intracellular potassium ion concentration in M. thermautotrophicus, our results suggest that the characterized thermophilic enzyme acts as an AP endonuclease in vivo with similar activities as Ape1...
  2. Georg J, Schomacher L, Chong J, Majern k A, Raabe M, Urlaub H, et al. The Methanothermobacter thermautotrophicus ExoIII homologue Mth212 is a DNA uridine endonuclease. Nucleic Acids Res. 2006;34:5325-36 pubmed publisher
    ..We have now identified protein Mth212, a member of the ExoIII family of nucleases, as a possible initiator of DNA uracil repair in this organism...
  3. Lakomek K, Dickmanns A, Ciirdaeva E, Schomacher L, Ficner R. Crystal structure analysis of DNA uridine endonuclease Mth212 bound to DNA. J Mol Biol. 2010;399:604-17 pubmed publisher
    ..The exonuclease III homologue Mth212 from the thermophilic archaeon M...