Gene Symbol: cxcl12
Description: C-X-C motif chemokine ligand 12
Alias: sdf1a, stromal cell-derived factor 1, chemokine (C-X-C motif) ligand 12b, cxcl12b/sdf1b, stromal cell-derived factor 1a
Species: medaka

Top Publications

  1. Nakamura S, Kobayashi D, Aoki Y, Yokoi H, Ebe Y, Wittbrodt J, et al. Identification and lineage tracing of two populations of somatic gonadal precursors in medaka embryos. Dev Biol. 2006;295:678-88 pubmed publisher
  2. Herpin A, Fischer P, Liedtke D, Kluever N, Neuner C, Raz E, et al. Sequential SDF1a and b-induced mobility guides Medaka PGC migration. Dev Biol. 2008;320:319-27 pubmed publisher zebrafish, where proper PGC positioning is the result of active migration in the direction of the source of SDF1a, Medaka PGC movements are shown to be the consequence of a combination of active SDF1a and SDF1b-guided migration...
  3. Sasado T, Kondoh H, Furutani Seiki M, Naruse K. Mutation in cpsf6/CFIm68 (Cleavage and Polyadenylation Specificity Factor Subunit 6) causes short 3'UTRs and disturbs gene expression in developing embryos, as revealed by an analysis of primordial germ cell migration using the medaka mutant naruto. PLoS ONE. 2017;12:e0172467 pubmed publisher
    ..primordial germ cell (PGC) migration identified cxcr4b and cxcr7, which are both receptors of the chemokine sdf1/cxcl12, as key regulators of PGC migration...