Gene Symbol: amh
Description: anti-Mullerian hormone
Alias: muellerian-inhibiting factor
Kl ver N, Pfennig F, Pala I, Storch K, Schlieder M, Froschauer A, et al
. Differential expression of anti-Müllerian hormone (amh) and anti-Müllerian hormone receptor type II (amhrII) in the teleost medaka. Dev Dyn. 2007;236:271-81 pubmed publisher
In mammals, the anti-Müllerian hormone (Amh) is responsible for the regression of the Müllerian ducts; therefore, Amh is an important factor of male sex differentiation...
Shiraishi E, Yoshinaga N, Miura T, Yokoi H, Wakamatsu Y, Abe S, et al
. Mullerian inhibiting substance is required for germ cell proliferation during early gonadal differentiation in medaka (Oryzias latipes). Endocrinology. 2008;149:1813-9 pubmed publisher
..These results suggest that in medaka, MIS indirectly stimulates germ cell proliferation through MISRII, expressed in the somatic cells immediately after they reach the gonadal primordium...
Nakamura S, Kobayashi D, Aoki Y, Yokoi H, Ebe Y, Wittbrodt J, et al
. Identification and lineage tracing of two populations of somatic gonadal precursors in medaka embryos. Dev Biol. 2006;295:678-88 pubmed publisher
Nakamura S, Watakabe I, Nishimura T, Picard J, Toyoda A, Taniguchi Y, et al
. Hyperproliferation of mitotically active germ cells due to defective anti-Müllerian hormone signaling mediates sex reversal in medaka. Development. 2012;139:2283-7 pubmed publisher
The function of AMH (Anti-Müllerian hormone), a phylogenetically ancient member of the TGF? family of proteins, in lower vertebrates is largely unknown...