Gene Symbol: L
Description: large subunit of RNA dependent RNA polymerase (RdRp); RNA synthesis, capping, and polyadenylation
Alias: large subunit of RNA dependent RNA polymerase (RdRp), RNA synthesis, capping, and polyadenylation, large polymerase protein
Species: Measles virus

Top Publications

  1. Wardrop E, Briedis D. Characterization of V protein in measles virus-infected cells. J Virol. 1991;65:3421-8 pubmed
  2. Cattaneo R, Kaelin K, Baczko K, Billeter M. Measles virus editing provides an additional cysteine-rich protein. Cell. 1989;56:759-64 pubmed
    ..A smaller fraction of transcripts contain several additional G residues...
  3. Bellini W, Englund G, Richardson C, Rozenblatt S, Lazzarini R. Matrix genes of measles virus and canine distemper virus: cloning, nucleotide sequences, and deduced amino acid sequences. J Virol. 1986;58:408-16 pubmed
    ..M. Blumberg, K. Rose, M. G. Simona, L. Roux, C. Giorgi, and D. Kolakofsky, J. Virol. 52:656-663; Y. Hidaka, T. Kanda, K. Iwasaki, A. Nomoto, T...
  4. Krumm S, Takeda M, Plemper R. The measles virus nucleocapsid protein tail domain is dispensable for viral polymerase recruitment and activity. J Biol Chem. 2013;288:29943-53 pubmed publisher
    ..Dispensable for polymerase recruitment, N-MoRE binding to P-tail stabilizes the advancing polymerase-RNP complex and may rearrange unstructured central tail sections to facilitate polymerase access to the template. ..
  5. Bellini W, Englund G, Rozenblatt S, Arnheiter H, Richardson C. Measles virus P gene codes for two proteins. J Virol. 1985;53:908-19 pubmed
    ..Using immunofluorescent microscopy, we localized the C protein in the nucleus and in cytoplasmic inclusions within the infected cells...
  6. Rima B, Duprex W. The measles virus replication cycle. Curr Top Microbiol Immunol. 2009;329:77-102 pubmed
  7. Takeuchi K, Miyajima N, Kobune F, Tashiro M. Comparative nucleotide sequence analyses of the entire genomes of B95a cell-isolated and vero cell-isolated measles viruses from the same patient. Virus Genes. 2000;20:253-7 pubmed
    ..These results indicated that nucleotide difference(s) in the P/V/C or/and M gene, and not H gene, was responsible for the different cell tropism and pathogenicity of MV in this case...
  8. Cevik B, Holmes D, Vrotsos E, Feller J, Smallwood S, Moyer S. The phosphoprotein (P) and L binding sites reside in the N-terminus of the L subunit of the measles virus RNA polymerase. Virology. 2004;327:297-306 pubmed
    Measles virus encodes an RNA-dependent RNA polymerase composed of the L and P proteins. Recent studies have shown that the L proteins of both Sendai virus and parainfluenza virus 3 form an L-L complex [Cevik, B., Smallwood, S., Moyer, S...