sigB

Summary

Gene Symbol: sigB
Description: RNA polymerase sigma factor SigB
Species: Listeria monocytogenes EGD-e

Top Publications

  1. Wiedmann M, Arvik T, Hurley R, Boor K. General stress transcription factor sigmaB and its role in acid tolerance and virulence of Listeria monocytogenes. J Bacteriol. 1998;180:3650-6 pubmed
    ..monocytogenes sigB operon is rsbU-rsbV-rsbW-sigB-rsbX and is therefore identical to the order of the last five genes of the B...
  2. Asakura H, Kawamoto K, Okada Y, Kasuga F, Makino S, Yamamoto S, et al. Intrahost passage alters SigB-dependent acid resistance and host cell-associated kinetics of Listeria monocytogenes. Infect Genet Evol. 2012;12:94-101 pubmed publisher
    ..Genetic and proteomic analyses revealed a link between acid resistance and SigB (RNA polymerase SigmaB subunit) activity...
  3. Nielsen J, Olsen A, Bonde M, Valentin Hansen P, Kallipolitis B. Identification of a sigma B-dependent small noncoding RNA in Listeria monocytogenes. J Bacteriol. 2008;190:6264-70 pubmed publisher
    ..This finding adds the sigma(B) regulon to the growing list of stress-induced regulatory circuits that include small noncoding RNAs...
  4. van der Veen S, Abee T. Importance of SigB for Listeria monocytogenes static and continuous-flow biofilm formation and disinfectant resistance. Appl Environ Microbiol. 2010;76:7854-60 pubmed publisher
    ..In this study, we investigated the role of sigB, which encodes a major transcriptional regulator of stress response genes, in L...
  5. Boura M, Keating C, Royet K, Paudyal R, O Donoghue B, O Byrne C, et al. Loss of SigB in Listeria monocytogenes Strains EGD-e and 10403S Confers Hyperresistance to Hydrogen Peroxide in Stationary Phase under Aerobic Conditions. Appl Environ Microbiol. 2016;82:4584-4591 pubmed publisher
    b>SigB is the main stress gene regulator in Listeria monocytogenes affecting the expression of more than 150 genes and thus contributing to multiple-stress resistance...
  6. Zhang Q, Feng Y, Deng L, Feng F, Wang L, Zhou Q, et al. SigB plays a major role in Listeria monocytogenes tolerance to bile stress. Int J Food Microbiol. 2011;145:238-43 pubmed publisher
    ..monocytogenes grows under hypoxemic condition. As the bsh promoter contains consensus SigB and PrfA binding sites, we investigated the role of SigB (?(B)) and PrfA in L...
  7. Ondrusch N, Kreft J. Blue and red light modulates SigB-dependent gene transcription, swimming motility and invasiveness in Listeria monocytogenes. PLoS ONE. 2011;6:e16151 pubmed publisher
    ..bacteria, including Listeria, the general stress response is regulated by the alternative sigma factor B (SigB)...
  8. O Donoghue B, NicAogáin K, Bennett C, Conneely A, Tiensuu T, Johansson J, et al. Blue-Light Inhibition of Listeria monocytogenes Growth Is Mediated by Reactive Oxygen Species and Is Influenced by σB and the Blue-Light Sensor Lmo0799. Appl Environ Microbiol. 2016;82:4017-4027 pubmed publisher
    ..sensory protein Lmo0799, leading to activation of the general stress response sigma factor SigB (σ(B)). In this study, we investigated the physiological response of this foodborne pathogen to blue light...
  9. Rauch M, Luo Q, M ller Altrock S, Goebel W. SigB-dependent in vitro transcription of prfA and some newly identified genes of Listeria monocytogenes whose expression is affected by PrfA in vivo. J Bacteriol. 2005;187:800-4 pubmed publisher
    ..47:1613-1625, 2003). In vitro transcription performed with promoters of some class III genes showed strict SigB-dependent but PrfA-independent transcription initiation...

More Information

Publications15

  1. Cai S, Kabuki D, Kuaye A, Cargioli T, Chung M, Nielsen R, et al. Rational design of DNA sequence-based strategies for subtyping Listeria monocytogenes. J Clin Microbiol. 2002;40:3319-25 pubmed
    ..Two housekeeping genes (recA and prs), one stress response gene (sigB), two virulence genes (actA and inlA), and two intergenic regions (hly-mpl and plcA-hly) were sequenced for 15 L...
  2. Ollinger J, Wiedmann M, Boor K. SigmaB- and PrfA-dependent transcription of genes previously classified as putative constituents of the Listeria monocytogenes PrfA regulon. Foodborne Pathog Dis. 2008;5:281-93 pubmed publisher
    ..While the sigB deletion significantly affected transcript levels for the selected group III genes (i.e...
  3. Ait Ouazzou A, Ma as P, Cond n S, Pag n R, Garc a Gonzalo D. Role of general stress-response alternative sigma factors ?(S) (RpoS) and ?(B) (SigB) in bacterial heat resistance as a function of treatment medium pH. Int J Food Microbiol. 2012;153:358-64 pubmed publisher
    ..aimed to determine the role of general stress-response alternative sigma factors ?(S) (RpoS) and ?(B) (SigB) in heat resistance and the occurrence of sublethal injuries in cell envelopes of stationary-phase Escherichia coli ..
  4. Utratna M, Cosgrave E, Baustian C, Ceredig R, O Byrne C. Effects of growth phase and temperature on ?B activity within a Listeria monocytogenes population: evidence for RsbV-independent activation of ?B at refrigeration temperatures. Biomed Res Int. 2014;2014:641647 pubmed publisher
    ..monocytogenes EGD-e wild-type, ?sigB, and ?rsbV throughout growth at both 4°C and 37°C, using a reporter fusion that couples expression of EGFP to the ..
  5. Begley M, Hill C, Ross R. Tolerance of Listeria monocytogenes to cell envelope-acting antimicrobial agents is dependent on SigB. Appl Environ Microbiol. 2006;72:2231-4 pubmed
    Mutation of sigB impairs the ability of Listeria monocytogenes to grow in sublethal levels, and to survive in lethal concentrations, of the bacteriocins nisin and lacticin 3147 and the antibiotics ampicillin and penicillin G...
  6. Zhou Q, Wang L, Yin X, Feng X, Shang J, Luo Q. SigB-dependent tolerance to protein synthesis-inhibiting antibiotics in Listeria monocytogenes EGDe. Curr Microbiol. 2012;64:234-41 pubmed publisher
    The alternative sigma factor SigB in food-borne pathogen Listeria monocytogenes was determined in this study to be required for tolerance to protein synthesis-inhibiting antibiotics...