Gene Symbol: ORF00044
Description: insertion sequence IS946 transposase
Species: Lactococcus lactis
Haandrikman A, van Leeuwen C, Kok J, Vos P, de Vos W, Venema G. Insertion elements on lactococcal proteinase plasmids. Appl Environ Microbiol. 1990;56:1890-6 pubmed
..On pWV05, ISS1W is flanked on one side by only part of a second IS element, indicating that pWV05 evolved as a deletion derivative of a precursor plasmid that carried at least two IS elements. ..
Polzin K, Shimizu Kadota M. Identification of a new insertion element, similar to gram-negative IS26, on the lactose plasmid of Streptococcus lactis ML3. J Bacteriol. 1987;169:5481-8 pubmed
..5% identical) of the open reading of frame. ..
Romero D, Klaenhammer T. Characterization of insertion sequence IS946, an Iso-ISS1 element, isolated from the conjugative lactococcal plasmid pTR2030. J Bacteriol. 1990;172:4151-60 pubmed
..IS946 has perfect 18-bp terminal inverted repeats, identical to ISS1, and similarly generated 8-bp direct repeats of the target site upon insertion. ..
Huang D, Novel M, Huang X, Novel G. Nonidentity between plasmid and chromosomal copies of ISS1-like sequences in Lactococcus lactis subsp. lactis CNRZ270 and their possible role in chromosomal integration of plasmid genes. Gene. 1992;118:39-46 pubmed
..ISS1-like sequences were also found on plasmids of numerous Lc. lactis strains, as well as one out of seven Lactobacillus (Lb.) casei and one out of three Lb. plantarum strains examined. ..
Ward L, Brown J, Davey G. Identification and sequence analysis of IS1297, an ISS1-like insertion sequence in a Leuconostoc strain. Gene. 1996;174:259-63 pubmed
..This is the first sequence of an ISS1-like element from a genus other than Lactococcus; however, IS1297 has close similarity to the lactococcal iso-ISS1 elements, especially the iso-ISS1 element from the lactose plasmid, pTD1. ..
Cluzel P, Chopin A, Ehrlich S, Chopin M. Phage abortive infection mechanism from Lactococcus lactis subsp. lactis, expression of which is mediated by an Iso-ISS1 element. Appl Environ Microbiol. 1991;57:3547-51 pubmed
..The expression of abi-416 was shown to be mediated by the Iso-ISS1 element, which contains a sequence fitting the consensus sequence for gram-positive promoters. ..
Smigielski A. Characterization of a plasmid involved with cointegrate formation and lactose metabolism in Lactococcus lactis subsp. lactis OZS1. Arch Microbiol. 1990;154:560-5 pubmed
..lactis subsp. lactis strains and two L. lactis subsp. cremoris strains showed moderate to strong hybridization to one plasmid in each organism. ..