Gene Symbol: gnd
Description: 6-phosphogluconate dehydrogenase
Species: Lactococcus lactis subsp. cremoris MG1363
- 6-Phosphogluconate dehydrogenase from Lactococcus lactis: a role for arginine residues in binding substrate and coenzymeE Tetaud
Laboratoire de Biologie Moléculaire et Immunologie de Parasites Protozoaires, UPRESA 5016 CNRS, Universite Bordeaux II, France
Biochem J 338:55-60. 1999..A second 6-PGDH gene has been identified from the genome of B. subtilis. This second isoform contains an arginine (Arg-34) in this position, suggesting that B. subtilis has two 6-PGDHs with different coenzyme specificities...
- Crystal structures of a bacterial 6-phosphogluconate dehydrogenase reveal aspects of specificity, mechanism and mode of inhibition by analogues of high-energy reaction intermediatesRamasubramanian Sundaramoorthy
Division of Biological Chemistry and Molecular Microbiology, College of Life Sciences, University of Dundee, UK
FEBS J 274:275-86. 2007..LlPDH can now serve as a model system for structure-based inhibitor design targeting the enzyme from Trypanosoma species...