LSEI_0945

Summary

Gene Symbol: LSEI_0945
Description: HPr kinase/phosphorylase
Species: Lactobacillus casei ATCC 334

Top Publications

  1. Chaptal V, Vincent F, Gueguen Chaignon V, Monedero V, Poncet S, Deutscher J, et al. Structural analysis of the bacterial HPr kinase/phosphorylase V267F mutant gives insights into the allosteric regulation mechanism of this bifunctional enzyme. J Biol Chem. 2007;282:34952-7 pubmed publisher
    ..Together with nucleotide binding fluorescence measurements, these results allowed us to decipher the cooperative behavior of the protein and to gain new insights into the allosteric regulation mechanism of HPrK/P...
  2. Fieulaine S, Morera S, Poncet S, Monedero V, Gueguen Chaignon V, Galinier A, et al. X-ray structure of HPr kinase: a bacterial protein kinase with a P-loop nucleotide-binding domain. EMBO J. 2001;20:3917-27 pubmed publisher
    ..The results confirm that HprK/P represents a new family of protein kinases, first identified in bacteria, but which may also have members in eukaryotes...
  3. Fieulaine S, Morera S, Poncet S, Mijakovic I, Galinier A, Janin J, et al. X-ray structure of a bifunctional protein kinase in complex with its protein substrate HPr. Proc Natl Acad Sci U S A. 2002;99:13437-41 pubmed publisher
    ..This study provides the structure of a protein kinase in complex with its protein substrate, giving insights into the chemistry of the phospho-transfer reactions in both directions...