M1

Summary

Gene Symbol: M1
Description: matrix protein 1
Species: Influenza A virus (A/Goose/Guangdong/1/96(H5N1))

Top Publications

  1. Xu X, Cox N, Guo Y. Genetic characterization of the pathogenic influenza A/Goose/Guangdong/1/96 (H5N1) virus: similarity of its hemagglutinin gene to those of H5N1 viruses from the 1997 outbreaks in Hong Kong. Virology. 1999;261:15-9 pubmed
    ..These data suggest that the H5N1 viruses isolated from the Hong Kong outbreaks derived their HA genes from a virus similar to the A/Goose/Guangdong/1/96 virus or shared a progenitor with this goose pathogen...
  2. Nao N, Kajihara M, Manzoor R, Maruyama J, Yoshida R, Muramatsu M, et al. A Single Amino Acid in the M1 Protein Responsible for the Different Pathogenic Potentials of H5N1 Highly Pathogenic Avian Influenza Virus Strains. PLoS ONE. 2015;10:e0137989 pubmed publisher
    ..from wild ducks in Japan, were found to be genetically similar, with only two amino acid differences in their M1 and PB1 proteins at positions 43 and 317, respectively...
  3. . Evolution of H5N1 avian influenza viruses in Asia. Emerg Infect Dis. 2005;11:1515-21 pubmed publisher
    ..An updated nonpathogenic H5N1 reference virus, lacking the polybasic cleavage site in the hemagglutinin gene, was produced by reverse genetics in anticipation of the possible need to vaccinate humans...
  4. Shimizu K, Li C, Muramoto Y, Yamada S, Arikawa J, Chen H, et al. The nucleoprotein and matrix protein segments of H5N1 influenza viruses are responsible for dominance in embryonated eggs. J Gen Virol. 2011;92:1645-9 pubmed publisher
    ..These results suggest roles for these viral proteins in influenza virus dominance. ..
  5. Brunotte L, Flies J, Bolte H, Reuther P, Vreede F, Schwemmle M. The nuclear export protein of H5N1 influenza A viruses recruits Matrix 1 (M1) protein to the viral ribonucleoprotein to mediate nuclear export. J Biol Chem. 2014;289:20067-77 pubmed publisher
    ..polymerase, its function during nuclear export implicates interaction with viral ribonucleoprotein (vRNP)-associated M1. The observation that both interactions are mediated by the C-terminal moiety of NEP raised the question whether ..