Gene Symbol: ZZZ3
Description: zinc finger ZZ-type containing 3
Alias: ATAC1, ZZ-type zinc finger-containing protein 3, ATAC component 1 homolog, zinc finger, ZZ domain containing 3
Mi W, Zhang Y, Lyu J, Wang X, Tong Q, Peng D, et al
. The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation. Nat Commun. 2018;9:3759 pubmed publisher
..Here, we report the identification of a reader of histone H3, the ZZ-type zinc finger (ZZ) domain of ZZZ3, a subunit of the Ada-two-A-containing (ATAC) histone acetyltransferase complex...
Berndt S, Gustafsson S, Magi R, Ganna A, Wheeler E, Feitosa M, et al
. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet. 2013;45:501-12 pubmed publisher
..height detected in the distribution tails and 7 new loci (HNF4G, RPTOR, GNAT2, MRPS33P4, ADCY9, HS6ST3 and ZZZ3) for clinical classes of obesity...
Guelman S, Suganuma T, Florens L, Swanson S, Kiesecker C, Kusch T, et al
. Host cell factor and an uncharacterized SANT domain protein are stable components of ATAC, a novel dAda2A/dGcn5-containing histone acetyltransferase complex in Drosophila. Mol Cell Biol. 2006;26:871-82 pubmed
..revealed that, in addition to dAda3 and dGcn5, host cell factor (dHCF) and a novel SANT domain protein, named Atac1 (ATAC component 1), copurify with this complex...
Orpinell M, Fournier M, Riss A, Nagy Z, Krebs A, Frontini M, et al
. The ATAC acetyl transferase complex controls mitotic progression by targeting non-histone substrates. EMBO J. 2010;29:2381-94 pubmed publisher
..Thus, we have uncovered an essential function for ATAC in regulating Cyclin A activity and consequent mitotic progression. ..
Gatta R, Mantovani R. NF-Y affects histone acetylation and H2A.Z deposition in cell cycle promoters. Epigenetics. 2011;6:526-34 pubmed
..KAT2A/KAT2B and subunits of the SAGA and ATAC complexes (SPT20 and ZZZ3) are differentially regulated. Finally, the deposition of H2A.Z, which maps around the TSS, is also NF-Y-dependent...