Gene Symbol: ZZZ3
Description: zinc finger ZZ-type containing 3
Alias: ATAC1, ZZ-type zinc finger-containing protein 3, ATAC component 1 homolog, zinc finger, ZZ domain containing 3
Species: human
Products:     ZZZ3

Top Publications

  1. Mi W, Zhang Y, Lyu J, Wang X, Tong Q, Peng D, et al. The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation. Nat Commun. 2018;9:3759 pubmed publisher
    ..Here, we report the identification of a reader of histone H3, the ZZ-type zinc finger (ZZ) domain of ZZZ3, a subunit of the Ada-two-A-containing (ATAC) histone acetyltransferase complex...
  2. Berndt S, Gustafsson S, Magi R, Ganna A, Wheeler E, Feitosa M, et al. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet. 2013;45:501-12 pubmed publisher
    ..height detected in the distribution tails and 7 new loci (HNF4G, RPTOR, GNAT2, MRPS33P4, ADCY9, HS6ST3 and ZZZ3) for clinical classes of obesity...
  3. Guelman S, Suganuma T, Florens L, Swanson S, Kiesecker C, Kusch T, et al. Host cell factor and an uncharacterized SANT domain protein are stable components of ATAC, a novel dAda2A/dGcn5-containing histone acetyltransferase complex in Drosophila. Mol Cell Biol. 2006;26:871-82 pubmed
    ..revealed that, in addition to dAda3 and dGcn5, host cell factor (dHCF) and a novel SANT domain protein, named Atac1 (ATAC component 1), copurify with this complex...
  4. Orpinell M, Fournier M, Riss A, Nagy Z, Krebs A, Frontini M, et al. The ATAC acetyl transferase complex controls mitotic progression by targeting non-histone substrates. EMBO J. 2010;29:2381-94 pubmed publisher
    ..Thus, we have uncovered an essential function for ATAC in regulating Cyclin A activity and consequent mitotic progression. ..
  5. Gatta R, Mantovani R. NF-Y affects histone acetylation and H2A.Z deposition in cell cycle promoters. Epigenetics. 2011;6:526-34 pubmed
    ..KAT2A/KAT2B and subunits of the SAGA and ATAC complexes (SPT20 and ZZZ3) are differentially regulated. Finally, the deposition of H2A.Z, which maps around the TSS, is also NF-Y-dependent...