VPS37D

Summary

Gene Symbol: VPS37D
Description: VPS37D, ESCRT-I subunit
Alias: WBSCR24, vacuolar protein sorting-associated protein 37D, ESCRT-I complex subunit VPS37D, Williams Beuren syndrome chromosome region 24, Williams-Beuren syndrome critical region protein 24, vacuolar protein sorting 37 homolog D, vacuolar protein sorting 37D, williams-Beuren syndrome chromosomal region 24 protein, williams-Beuren syndrome region protein 24
Species: human
Products:     VPS37D

Top Publications

  1. Stuchell M, Garrus J, Muller B, Stray K, Ghaffarian S, McKinnon R, et al. The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding. J Biol Chem. 2004;279:36059-71 pubmed
    ..Taken together, these experiments define new components of the human ESCRT-I complex and characterize several TSG101 protein/protein interactions required for HIV-1 budding and infectivity. ..
  2. Morita E, Sandrin V, Chung H, Morham S, Gygi S, Rodesch C, et al. Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis. EMBO J. 2007;26:4215-27 pubmed
    ..These experiments suggest that the ESCRT pathway may be recruited to facilitate analogous membrane fission events during HIV budding, MVB vesicle formation, and the abscission stage of cytokinesis. ..
  3. Morita E, Sandrin V, Alam S, Eckert D, Gygi S, Sundquist W. Identification of human MVB12 proteins as ESCRT-I subunits that function in HIV budding. Cell Host Microbe. 2007;2:41-53 pubmed
    ..Taken together, these studies define the composition of human ESCRT-I complexes and indicate that the MVB12 subunits play a unique role in regulating ESCRT-mediated virus budding. ..
  4. Agromayor M, Soler N, Caballe A, Kueck T, Freund S, Allen M, et al. The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain. Structure. 2012;20:414-28 pubmed publisher
  5. Cornelis M, Byrne E, Esko T, Nalls M, Ganna A, Paynter N, et al. Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Mol Psychiatry. 2015;20:647-656 pubmed publisher