vimentin

Summary

Gene Symbol: vimentin
Description: vimentin
Alias: vimentin
Species: human
Products:     vimentin

Top Publications

  1. Mor Vaknin N, Punturieri A, Sitwala K, Markovitz D. Vimentin is secreted by activated macrophages. Nat Cell Biol. 2003;5:59-63 pubmed
    b>Vimentin is a widely expressed intermediate filament protein thought to be involved mainly in structural processes, such as wound healing. We now demonstrate that activated human macrophages secrete vimentin into the extracellular space...
  2. Ando S, Tanabe K, Gonda Y, Sato C, Inagaki M. Domain- and sequence-specific phosphorylation of vimentin induces disassembly of the filament structure. Biochemistry. 1989;28:2974-9 pubmed
    ..stoichiometric phosphorylation by either cAMP-dependent protein kinase or protein kinase C induces disassembly of vimentin filaments [Inagaki, M., Nishi, Y., Nishizawa, K., Matsuyama, M., & Sato, C...
  3. Qin Z, Kreplak L, Buehler M. Hierarchical structure controls nanomechanical properties of vimentin intermediate filaments. PLoS ONE. 2009;4:e7294 pubmed publisher
    ..Here we utilize an atomistic-level model of the human vimentin dimer and tetramer to study their response to mechanical tensile stress, and describe a detailed analysis of the ..
  4. Shirahata A, Sakata M, Sakuraba K, Goto T, Mizukami H, Saito M, et al. Vimentin methylation as a marker for advanced colorectal carcinoma. Anticancer Res. 2009;29:279-81 pubmed
    Recently, it was shown that the Vimentin gene, usually activated in mesenchymal cells, was highly methylated in colorectal carcinoma...
  5. Yamasaki T, Seki N, Yamada Y, Yoshino H, Hidaka H, Chiyomaru T, et al. Tumor suppressive microRNA?138 contributes to cell migration and invasion through its targeting of vimentin in renal cell carcinoma. Int J Oncol. 2012;41:805-17 pubmed publisher
    ..analysis (miR?138 transfectants and RCC clinical specimens) and TargetScan database studies showed that vimentin (VIM) is a promising candidate target gene of miR?138...
  6. Goldie K, Wedig T, Mitra A, Aebi U, Herrmann H, Hoenger A. Dissecting the 3-D structure of vimentin intermediate filaments by cryo-electron tomography. J Struct Biol. 2007;158:378-85 pubmed
    b>Vimentin polymerizes via complex lateral interactions of coiled-coil dimers into long, flexible filaments referred to as intermediate filaments (IFs)...
  7. Ivaska J, Vuoriluoto K, Huovinen T, Izawa I, Inagaki M, Parker P. PKCepsilon-mediated phosphorylation of vimentin controls integrin recycling and motility. EMBO J. 2005;24:3834-45 pubmed
    ..b>Vimentin, an intermediate filament protein upregulated upon epithelial cell transformation, is shown here to be a proximal ..
  8. Xu B, deWaal R, Mor Vaknin N, Hibbard C, Markovitz D, Kahn M. The endothelial cell-specific antibody PAL-E identifies a secreted form of vimentin in the blood vasculature. Mol Cell Biol. 2004;24:9198-206 pubmed
    ..and tandem mass spectrometry analysis of tryptic peptides to identify the PAL-E antigen as a secreted form of vimentin. Vimentin has been well characterized as an intracellular intermediate filament protein expressed broadly in ..
  9. Eriksson J, He T, Trejo Skalli A, Härmälä Braskén A, Hellman J, Chou Y, et al. Specific in vivo phosphorylation sites determine the assembly dynamics of vimentin intermediate filaments. J Cell Sci. 2004;117:919-32 pubmed
    ..of type-1 (PP1) and type-2A (PP2A) protein phosphatases in BHK-21 fibroblasts with calyculin-A, induced rapid vimentin phosphorylation in concert with disassembly of the IF polymers into soluble tetrameric vimentin oligomers...

More Information

Publications67

  1. Slawson C, Lakshmanan T, Knapp S, Hart G. A mitotic GlcNAcylation/phosphorylation signaling complex alters the posttranslational state of the cytoskeletal protein vimentin. Mol Biol Cell. 2008;19:4130-40 pubmed publisher
    ..b>Vimentin, an intermediate filament protein, is an M phase substrate for both Aurora B and OGT...
  2. Muller M, Bhattacharya S, Moore T, Prescott Q, Wedig T, Herrmann H, et al. Dominant cataract formation in association with a vimentin assembly disrupting mutation. Hum Mol Genet. 2009;18:1052-7 pubmed publisher
    ..The intermediate filament protein vimentin, which is highly expressed in lens fiber cells and in mesenchymal tissues, is a main structural determinant in ..
  3. Singh S, Sadacharan S, Su S, Belldegrun A, Persad S, Singh G. Overexpression of vimentin: role in the invasive phenotype in an androgen-independent model of prostate cancer. Cancer Res. 2003;63:2306-11 pubmed
    ..The gene coding for the intermediate filament protein vimentin was found to be highly up-regulated in the CL1 subline...
  4. Al Maghrebi M, Brulé H, Padkina M, Allen C, Holmes W, Zehner Z. The 3' untranslated region of human vimentin mRNA interacts with protein complexes containing eEF-1gamma and HAX-1. Nucleic Acids Res. 2002;30:5017-28 pubmed
    Previously, we have shown that the vimentin 3' untranslated region (3'UTR) contains a highly conserved region, which is sufficient for the perinuclear localization of a reporter mRNA...
  5. Lang S, Hyde C, Reid I, Hitchcock I, Hart C, Bryden A, et al. Enhanced expression of vimentin in motile prostate cell lines and in poorly differentiated and metastatic prostate carcinoma. Prostate. 2002;52:253-63 pubmed
    ..of cell lines and tissues was used to identify expression of cytokeratins 8 and 1, 5, 10, 14, vimentin, prostate specific antigen, prostate specific membrane antigen, androgen receptor, desmoglein, E-cadherin, beta1 ..
  6. Strelkov S, Herrmann H, Geisler N, Lustig A, Ivaninskii S, Zimbelmann R, et al. Divide-and-conquer crystallographic approach towards an atomic structure of intermediate filaments. J Mol Biol. 2001;306:773-81 pubmed
    ..structure determination, we have produced and characterised 17 overlapping soluble fragments of human IF protein vimentin. For six fragments ranging in length between 39 and 84 amino acid residues, conditions yielding macroscopic ..
  7. Nakatani Y, Tanioka T, Sunaga S, Murakami M, Kudo I. Identification of a cellular protein that functionally interacts with the C2 domain of cytosolic phospholipase A(2)alpha. J Biol Chem. 2000;275:1161-8 pubmed
    ..Peptide microsequencing revealed that purified P60 was identical to vimentin, a major component of the intermediate filament...
  8. Liu L, Jiang X, Zhou X, Wang D, Song X, Jiang H. Upregulation of vimentin and aberrant expression of E-cadherin/beta-catenin complex in oral squamous cell carcinomas: correlation with the clinicopathological features and patient outcome. Mod Pathol. 2010;23:213-24 pubmed publisher
    ..Using quantitative immunohistochemistry, we examined the expression of vimentin, E-cadherin, and beta-catenin in 83 oral squamous cell carcinoma patients, and the relationships between the ..
  9. Kim H, Nakamura F, Lee W, Hong C, Perez Sala D, McCulloch C. Regulation of cell adhesion to collagen via beta1 integrins is dependent on interactions of filamin A with vimentin and protein kinase C epsilon. Exp Cell Res. 2010;316:1829-44 pubmed publisher
    ..We previously reported that the actin cross-linking protein filamin A binds the intermediate filament protein vimentin and that these two proteins co-regulate cell spreading...
  10. Lin Y, Broedersz C, Rowat A, Wedig T, Herrmann H, MacKintosh F, et al. Divalent cations crosslink vimentin intermediate filament tail domains to regulate network mechanics. J Mol Biol. 2010;399:637-44 pubmed publisher
    ..Here, we study the elastic behavior of in vitro networks of the intermediate filament protein vimentin. Rheological experiments reveal that vimentin networks stiffen with increasing concentrations of Ca(2+) and Mg(2+)..
  11. Shoeman R, Sachse C, Höner B, Mothes E, Kaufmann M, Traub P. Cleavage of human and mouse cytoskeletal and sarcomeric proteins by human immunodeficiency virus type 1 protease. Actin, desmin, myosin, and tropomyosin. Am J Pathol. 1993;142:221-30 pubmed
    ..Nonmuscle myosin heavy chains were also cleaved by this enzyme in vitro. These data demonstrate that this protease can cause alterations in muscle cell ultrastructure in vitro that may be of clinical relevance in infected individuals. ..
  12. Vuoriluoto K, Haugen H, Kiviluoto S, Mpindi J, Nevo J, Gjerdrum C, et al. Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer. Oncogene. 2011;30:1436-48 pubmed publisher
    ..The intermediate filament protein vimentin is an important marker of EMT and a requisite regulator of mesenchymal cell migration...
  13. Perreau J, Lilienbaum A, Vasseur M, Paulin D. Nucleotide sequence of the human vimentin gene and regulation of its transcription in tissues and cultured cells. Gene. 1988;62:7-16 pubmed
    ..the identification and isolation by mRNA selection/translation of a recombinant clone containing 80% of the human vimentin gene sequence [Lilienbaum et al., EMBO J. 5 (1986) 2809-2814]...
  14. Brauksiepe B, Mujica A, Herrmann H, Schmidt E. The Serine/threonine kinase Stk33 exhibits autophosphorylation and phosphorylates the intermediate filament protein Vimentin. BMC Biochem. 2008;9:25 pubmed publisher
    Colocalization of Stk33 with vimentin by double immunofluorescence in certain cells indicated that vimentin might be a target for phosphorylation by the novel kinase Stk33...
  15. Shoeman R, Höner B, Stoller T, Kesselmeier C, Miedel M, Traub P, et al. Human immunodeficiency virus type 1 protease cleaves the intermediate filament proteins vimentin, desmin, and glial fibrillary acidic protein. Proc Natl Acad Sci U S A. 1990;87:6336-40 pubmed
    The intermediate filament proteins vimentin, desmin, and glial fibrillary acidic protein are cleaved in vitro by human immunodeficiency virus type 1 protease (HIV-1 PR)...
  16. Kirmse R, Portet S, Mücke N, Aebi U, Herrmann H, Langowski J. A quantitative kinetic model for the in vitro assembly of intermediate filaments from tetrameric vimentin. J Biol Chem. 2007;282:18563-72 pubmed
    ..complemented by mathematical modeling to investigate the kinetics of in vitro assembly of human recombinant vimentin. From the average length distributions of the resulting filaments measured at increasing assembly times we ..
  17. McInroy L, Määttä A. Down-regulation of vimentin expression inhibits carcinoma cell migration and adhesion. Biochem Biophys Res Commun. 2007;360:109-14 pubmed
    b>Vimentin is a type III Intermediate filament protein that is expressed frequently in epithelial carcinomas correlating with invasiveness and poor prognosis...
  18. Cheng C, Wang H, Chang C, Chu H, Chen C, Yu J, et al. MicroRNA-30a inhibits cell migration and invasion by downregulating vimentin expression and is a potential prognostic marker in breast cancer. Breast Cancer Res Treat. 2012;134:1081-93 pubmed publisher
    ..The functional interaction between the candidate miRNA, miR-30a, and the target gene, Vim, which codes for vimentin, a protein involved in epithelial-mesenchymal transition, was examined using the luciferase reporter assay, ..
  19. Whipple R, Balzer E, Cho E, Matrone M, Yoon J, Martin S. Vimentin filaments support extension of tubulin-based microtentacles in detached breast tumor cells. Cancer Res. 2008;68:5678-88 pubmed publisher
    ..associates strongly with intermediate filament proteins, we examined the contribution of cytokeratin and vimentin filaments to tumor cell microtentacles...
  20. Vora H, Patel N, Rajvik K, Mehta S, Brahmbhatt B, Shah M, et al. Cytokeratin and vimentin expression in breast cancer. Int J Biol Markers. 2009;24:38-46 pubmed
    The transition from epithelial keratin to mesenchymal vimentin expression marks an important step in the malignant progression of breast cancer...
  21. Meier M, Padilla G, Herrmann H, Wedig T, Hergt M, Patel T, et al. Vimentin coil 1A-A molecular switch involved in the initiation of filament elongation. J Mol Biol. 2009;390:245-61 pubmed publisher
    ..our previously published structure of the coil 1A fragment of the human intermediate filament protein vimentin turned out to be a monomeric alpha-helical coil instead of the expected dimeric coiled coil...
  22. Bhattacharya R, Gonzalez A, DeBiase P, Trejo H, Goldman R, Flitney F, et al. Recruitment of vimentin to the cell surface by beta3 integrin and plectin mediates adhesion strength. J Cell Sci. 2009;122:1390-400 pubmed publisher
    ..However, vimentin intermediate filaments (IFs) also associate with the cell surface at FAs in endothelial cells...
  23. Goto H, Tanabe K, Manser E, Lim L, Yasui Y, Inagaki M. Phosphorylation and reorganization of vimentin by p21-activated kinase (PAK). Genes Cells. 2002;7:91-7 pubmed
    Intermediate filament (IF) is one of the three major cytoskeletal filaments. Vimentin is the most widely expressed IF protein component...
  24. Matsuzawa K, Kosako H, Inagaki N, Shibata H, Mukai H, Ono Y, et al. Domain-specific phosphorylation of vimentin and glial fibrillary acidic protein by PKN. Biochem Biophys Res Commun. 1997;234:621-5 pubmed
    ..yeast two-hybrid system and in vitro binding assay, we found that the regulatory domain of PKN interacted with vimentin. We then examined whether PKN would phosphorylate vimentin in vitro...
  25. Shoeman R, Hüttermann C, Hartig R, Traub P. Amino-terminal polypeptides of vimentin are responsible for the changes in nuclear architecture associated with human immunodeficiency virus type 1 protease activity in tissue culture cells. Mol Biol Cell. 2001;12:143-54 pubmed
    ..Similar changes were observed in SW 13 T3 M [vimentin(+)] cells, whereas no changes were observed in SW 13 [vimentin(-)] cells after microinjection of protease...
  26. Tsujimura K, Ogawara M, Takeuchi Y, Imajoh Ohmi S, Ha M, Inagaki M. Visualization and function of vimentin phosphorylation by cdc2 kinase during mitosis. J Biol Chem. 1994;269:31097-106 pubmed
    ..by cdc2 kinase during mitosis, we developed a monoclonal antibody 4A4 recognizing Ser55-phosphorylated vimentin. Western blotting indicated that this antibody reacted with vimentin phosphorylated by cdc2 kinase but not with ..
  27. Podor T, Singh D, Chindemi P, Foulon D, McKelvie R, Weitz J, et al. Vimentin exposed on activated platelets and platelet microparticles localizes vitronectin and plasminogen activator inhibitor complexes on their surface. J Biol Chem. 2002;277:7529-39 pubmed
    ..PAI-1 to platelet surfaces through a high affinity (K(d) of 80 nm) binding interaction with the NH(2) terminus of vimentin, and this Vn-binding domain is expressed on the surface of activated platelets and platelet microparticles...
  28. Strelkov S, Herrmann H, Geisler N, Wedig T, Zimbelmann R, Aebi U, et al. Conserved segments 1A and 2B of the intermediate filament dimer: their atomic structures and role in filament assembly. EMBO J. 2002;21:1255-66 pubmed
    ..Based on the crystal structures of three human vimentin fragments at 1.4-2...
  29. Gilles C, Polette M, Mestdagt M, Nawrocki Raby B, Ruggeri P, Birembaut P, et al. Transactivation of vimentin by beta-catenin in human breast cancer cells. Cancer Res. 2003;63:2658-64 pubmed
    The cytoplasmic and nuclear redistribution of beta-catenin and the de novo expression of vimentin are frequently involved in the epithelial-to-mesenchymal transition associated with increased invasive/migratory properties of epithelial ..
  30. Boilard E, Bourgoin S, Bernatchez C, Surette M. Identification of an autoantigen on the surface of apoptotic human T cells as a new protein interacting with inflammatory group IIA phospholipase A2. Blood. 2003;102:2901-9 pubmed
    ..Using matrix-assisted laser desorption/ionization time of flight (MALDI-TOF) mass spectrometry we now identify vimentin as the major HSPG-independent binding protein of hGIIA on apoptotic primary T lymphocytes...
  31. Kreis S, Schönfeld H, Melchior C, Steiner B, Kieffer N. The intermediate filament protein vimentin binds specifically to a recombinant integrin alpha2/beta1 cytoplasmic tail complex and co-localizes with native alpha2/beta1 in endothelial cell focal adhesions. Exp Cell Res. 2005;305:110-21 pubmed
    ..beta1 heterodimeric complex, but not the single subunits, interacted specifically with endothelial cell-derived vimentin. Vimentin, an abundant intermediate filament protein, has previously been shown to co-localize with alphavbeta3-..
  32. Höner B, Shoeman R, Traub P. Human immunodeficiency virus type 1 protease microinjected into cultured human skin fibroblasts cleaves vimentin and affects cytoskeletal and nuclear architecture. J Cell Sci. 1991;100 ( Pt 4):799-807 pubmed
    ..Thereafter, the vimentin intermediate filament (IF) network collapsed. No effect was seen on the microtubules...
  33. Zou Y, He L, Huang S. Identification of a surface protein on human brain microvascular endothelial cells as vimentin interacting with Escherichia coli invasion protein IbeA. Biochem Biophys Res Commun. 2006;351:625-30 pubmed
    ..Here, we identified a surface protein on human BMEC, vimentin, that interacts with the E. coli invasion protein IbeA...
  34. Helfand B, Mendez M, Murthy S, Shumaker D, Grin B, Mahammad S, et al. Vimentin organization modulates the formation of lamellipodia. Mol Biol Cell. 2011;22:1274-89 pubmed publisher
    b>Vimentin intermediate filaments (VIF) extend throughout the rear and perinuclear regions of migrating fibroblasts, but only nonfilamentous vimentin particles are present in lamellipodial regions...
  35. Sokolova A, Kreplak L, Wedig T, Mücke N, Svergun D, Herrmann H, et al. Monitoring intermediate filament assembly by small-angle x-ray scattering reveals the molecular architecture of assembly intermediates. Proc Natl Acad Sci U S A. 2006;103:16206-11 pubmed
    ..applied solution small-angle x-ray scattering to investigate the in vitro assembly of a 53-kDa human IF protein vimentin at pH 8...
  36. Starr A, Bellac C, Dufour A, Goebeler V, Overall C. Biochemical characterization and N-terminomics analysis of leukolysin, the membrane-type 6 matrix metalloprotease (MMP25): chemokine and vimentin cleavages enhance cell migration and macrophage phagocytic activities. J Biol Chem. 2012;287:13382-95 pubmed publisher
    ..b>Vimentin, cystatin C, galectin-1, IGFBP-7, and secreted protein, acidic and rich in cysteine (SPARC) were among those ..
  37. Sommers C, Walker Jones D, Heckford S, Worland P, Valverius E, Clark R, et al. Vimentin rather than keratin expression in some hormone-independent breast cancer cell lines and in oncogene-transformed mammary epithelial cells. Cancer Res. 1989;49:4258-63 pubmed
    ..One clone, which was isolated in many copies, coded for the intermediate filament protein vimentin. A complementary DNA clone 1.8 kilobases long included the entire protein-coding region for vimentin...
  38. Costa V, Henrique R, Danielsen S, Duarte Pereira S, Eknaes M, Skotheim R, et al. Three epigenetic biomarkers, GDF15, TMEFF2, and VIM, accurately predict bladder cancer from DNA-based analyses of urine samples. Clin Cancer Res. 2010;16:5842-51 pubmed publisher
    ..By using a genome-wide approach, we have identified a biomarker panel that allows for early and accurate noninvasive detection of BlCa using urine samples. ..
  39. Zhu Q, Rosenblatt K, Huang K, Lahat G, Brobey R, Bolshakov S, et al. Vimentin is a novel AKT1 target mediating motility and invasion. Oncogene. 2011;30:457-70 pubmed publisher
    ..STS cell motility and invasiveness at least partially through a novel interaction with the intermediate filament vimentin (Vim)...
  40. Van Steendam K, Tilleman K, De Ceuleneer M, De Keyser F, Elewaut D, Deforce D. Citrullinated vimentin as an important antigen in immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteins. Arthritis Res Ther. 2010;12:R132 pubmed publisher
    ..Additionally, in IC isolated from RA SF, fibrinogen? and vimentin were identified as well...
  41. Morishima N. Changes in nuclear morphology during apoptosis correlate with vimentin cleavage by different caspases located either upstream or downstream of Bcl-2 action. Genes Cells. 1999;4:401-14 pubmed
    ..We have found that an intermediate filament protein, vimentin, is cleaved at multiple sites by caspases at an early stage of apoptosis in Jurkat cells...
  42. Zhang Q, Helfand B, Jang T, Zhu L, Chen L, Yang X, et al. Nuclear factor-kappaB-mediated transforming growth factor-beta-induced expression of vimentin is an independent predictor of biochemical recurrence after radical prostatectomy. Clin Cancer Res. 2009;15:3557-67 pubmed publisher
    ..Blockade of NF-kappaB or TGF-beta signaling resulted in abrogation of vimentin expression and inhibition of the invasive capability of these cells...
  43. Byun Y, Chen F, Chang R, Trivedi M, Green K, Cryns V. Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis. Cell Death Differ. 2001;8:443-50 pubmed
    ..recently developed to identify cDNAs encoding caspase substrates, we isolated the intermediate filament protein vimentin as a caspase substrate...
  44. Cheng T, Tseng Y, Chang W, Chang M, Lai Y. Retaining of the assembly capability of vimentin phosphorylated by mitogen-activated protein kinase-activated protein kinase-2. J Cell Biochem. 2003;89:589-602 pubmed
    Intermediate filament (IF) networks can be regulated by phosphorylation of unit proteins, such as vimentin, by specific kinases leading to reorganization of the IF filamentous structure...
  45. Zhao Y, Yan Q, Long X, Chen X, Wang Y. Vimentin affects the mobility and invasiveness of prostate cancer cells. Cell Biochem Funct. 2008;26:571-7 pubmed publisher
    ..Here, we investigated vimentin expression of prostate cancer cells, and explored the potential mechanism of vimentin promoting prostate cancer ..
  46. Trog D, Yeghiazaryan K, Schild H, Golubnitschaja O. Up-regulation of vimentin expression in low-density malignant glioma cells as immediate and late effects under irradiation and temozolomide treatment. Amino Acids. 2008;34:539-45 pubmed
    ..Expressional profiling of vimentin--one of reliable pro-invasive tumor makers--in those simulation models was the goal of this study, in order to ..
  47. Moisan E, Girard D. Cell surface expression of intermediate filament proteins vimentin and lamin B1 in human neutrophil spontaneous apoptosis. J Leukoc Biol. 2006;79:489-98 pubmed
    ..To date, two cytoskeletal proteins, vinculin and vimentin, have been reported to be expressed on the cell surfaces of activated macrophages, platelets, and apoptotic T ..
  48. Goto H, Kosako H, Tanabe K, Yanagida M, Sakurai M, Amano M, et al. Phosphorylation of vimentin by Rho-associated kinase at a unique amino-terminal site that is specifically phosphorylated during cytokinesis. J Biol Chem. 1998;273:11728-36 pubmed
    We found that vimentin, the most widely expressed intermediate filament protein, served as an excellent substrate for Rho-associated kinase (Rho-kinase) and that vimentin phosphorylated by Rho-kinase lost its ability to form filaments in ..
  49. Otsuki S, Inokuchi M, Enjoji M, Ishikawa T, Takagi Y, Kato K, et al. Vimentin expression is associated with decreased survival in gastric cancer. Oncol Rep. 2011;25:1235-42 pubmed publisher
    ..In some cancers, expression of vimentin, a mesenchymal maker, is associated with poor survival...
  50. Dortet L, Cuzon G, Plésiat P, Naas T. Prospective evaluation of an algorithm for the phenotypic screening of carbapenemase-producing Enterobacteriaceae. J Antimicrob Chemother. 2016;71:135-40 pubmed publisher
    ..Implementation of the CA-SFM algorithm in clinical microbiology laboratories may avoid additional testing for CPE in one-third of the enterobacterial isolates with decreased susceptibility to carbapenems. ..
  51. Mücke N, Winheim S, Merlitz H, Buchholz J, Langowski J, Herrmann H. In Vitro Assembly Kinetics of Cytoplasmic Intermediate Filaments: A Correlative Monte Carlo Simulation Study. PLoS ONE. 2016;11:e0157451 pubmed publisher
  52. Falco A, Ramos Y, Franco E, Guzmán A, Takiff H. A cluster of KPC-2 and VIM-2-producing Klebsiella pneumoniae ST833 isolates from the pediatric service of a Venezuelan Hospital. BMC Infect Dis. 2016;16:595 pubmed
    ..pneumoniae sensitive to QACs. This analysis may help to understand the routes of dissemination and confirms that QAC disinfectants can be used to help control their spread. ..
  53. Beris F, Budak E, Gülek D, Uzun A, Cizmeci Z, Mengeloğlu F, et al. [Investigation of the frequency and distribution of beta-lactamase genes in the clinical isolates of Acinetobacter baumannii collected from different regions of Turkey: a multicenter study]. Mikrobiyol Bul. 2016;50:511-521 pubmed
    ..7%) amongst A.baumannii strains isolated from different regions of our country. The data of our study is parallel to the results of previous studies carried out from Turkey. ..
  54. Hoshide S, Yano Y, Mizuno H, Kanegae H, Kario K. Day-by-Day Variability of Home Blood Pressure and Incident Cardiovascular Disease in Clinical Practice: The J-HOP Study (Japan Morning Surge-Home Blood Pressure). Hypertension. 2018;71:177-184 pubmed publisher
    ..In addition to the assessments of mean home SBP levels and cardiovascular end-organ damage, home BP variability measurements may provide a clinically useful distinction between high- and low-risk groups among Japanese outpatients. ..
  55. Katarzyńska Banasik D, Grzesiak M, Sechman A. Selection of reference genes for quantitative real-time PCR analysis in chicken ovary following silver nanoparticle treatment. Environ Toxicol Pharmacol. 2017;56:186-190 pubmed publisher
    ..The outcome from the NormFinder is considered to be the most trustworthy and used in further qPCR analysis. ..
  56. Mirsalehian A, Kalantar Neyestanaki D, Taherikalani M, Jabalameli F, Emaneini M. Determination of carbapenem resistance mechanism in clinical isolates of Pseudomonas aeruginosa isolated from burn patients, in Tehran, Iran. J Epidemiol Glob Health. 2017;7:155-159 pubmed publisher
    ..6% of MDR-PA isolates. Although the presence of carbapenemase is the common mechanism of resistant to carbapenem, but carbapenem resistance was found by oprD mutation-driven and the AmpC overproducing isolates in Tehran, Iran. ..
  57. Murata H, Sakaguchi M, Kataoka K, Huh N. SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria. Mol Biol Cell. 2013;24:2772-84 pubmed publisher
    ..Some pathogenic mutations of PINK1 reduce the complex formation and ubiquitination. These results indicate that association of PINK1 with SARM1 and TRAF6 is an important step for mitophagy. ..
  58. Zhao W, Yue L, Zhou F, Xu C, Liang W, Sui A, et al. Clinical significance of vimentin expression and Her-2 status in patients with gastric carcinoma. Clin Transl Sci. 2013;6:184-90 pubmed publisher
    To determine whether vimentin could be used as a marker of gastric carcinomas with more aggressive behavior...