Gene Symbol: VAMP3
Description: vesicle associated membrane protein 3
Alias: CEB, vesicle-associated membrane protein 3, VAMP-3, cellubrevin, synaptobrevin-3
Species: human
Products:     VAMP3

Top Publications

  1. Prekeris R, Klumperman J, Chen Y, Scheller R. Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes. J Cell Biol. 1998;143:957-71 pubmed
    ..These results support a role for syntaxin 13 in membrane fusion events during the recycling of plasma membrane proteins. ..
  2. Gordon D, Mirza M, Sahlender D, Jakovleska J, Peden A. Coiled-coil interactions are required for post-Golgi R-SNARE trafficking. EMBO Rep. 2009;10:851-6 pubmed publisher
    ..However, when the dileucine motif is mutated, the construct can still be internalized potentially through coiled-coil interactions with Q-SNAREs. ..
  3. Galli T, Zahraoui A, Vaidyanathan V, Raposo G, Tian J, Karin M, et al. A novel tetanus neurotoxin-insensitive vesicle-associated membrane protein in SNARE complexes of the apical plasma membrane of epithelial cells. Mol Biol Cell. 1998;9:1437-48 pubmed
    ..codistributed at the apical plasma membrane where they formed NEM-dependent SNARE complexes with TI-VAMP and cellubrevin. We suggest that TI-VAMP, SNAP23, and syntaxin 3 can participate in exocytotic processes at the apical plasma ..
  4. Antonin W, Holroyd C, Fasshauer D, Pabst S, von Mollard G, Jahn R. A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function. EMBO J. 2000;19:6453-64 pubmed publisher
    ..We conclude that the structure of core complexes and their molecular mechanism in membrane fusion is highly conserved between distant SNAREs...
  5. Antonin W, Fasshauer D, Becker S, Jahn R, Schneider T. Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs. Nat Struct Biol. 2002;9:107-11 pubmed
    ..We conclude that the structure of the SNARE core complex is an evolutionarily conserved hallmark of all SNARE complexes and is intimately associated with the general role of SNAREs in membrane fusion. ..
  6. Mallard F, Tang B, Galli T, Tenza D, Saint Pol A, Yue X, et al. Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform. J Cell Biol. 2002;156:653-64 pubmed
    ..putative t-SNAREs syntaxin 6, syntaxin 16, and Vti1a, and two early/recycling endosomal v-SNAREs, VAMP3/cellubrevin, and VAMP4...
  7. Jiang C, Tang X, Tan H, Feng F, Xu Z, Mahmood Q, et al. Effect of scrubbing by NaClO backwashing on membrane fouling in anammox MBR. Sci Total Environ. 2019;670:149-157 pubmed publisher
    NaClO based chemically enhanced backwash (CEB) is often administered to maintain membrane permeability during the operation of MBR. However, the effect and working mechanism of NaClO concentrations in CEB were rarely investigated...
  8. Yang L, Peng X, Li Y, Zhang X, Ma Y, Wu C, et al. Long non-coding RNA HOTAIR promotes exosome secretion by regulating RAB35 and SNAP23 in hepatocellular carcinoma. Mol Cancer. 2019;18:78 pubmed publisher
    ..The mechanism of HOTAIR's regulation of Ras-related protein Rab-35 (RAB35), vesicle associated membrane protein 3 (VAMP3), and SNAP23 was assessed using confocal co-localization analysis, phosphorylation assays, ..
  9. Peng Y, Wang Q, Ying L, Kamel M, Peng H. Numerical Simulation of Dynamic Mechanical Properties of Concrete under Uniaxial Compression. Materials (Basel). 2019;12: pubmed publisher
    ..enhancement factors are in a good agreement with the formula given by the Comité Euro-International du Béton (CEB) and other experimental results...

More Information

Publications116 found, 100 shown here

  1. Takeuchi T, Harada Y, Moriyama S, Furuta K, Tanaka S, Miyaji T, et al. Vesicular Polyamine Transporter Mediates Vesicular Storage and Release of Polyamine from Mast Cells. J Biol Chem. 2017;292:3909-3918 pubmed publisher
    ..Immunohistochemical analysis indicated that VPAT is colocalized with VAMP3 but not with histamine, serotonin, cathepsin D, VAMP2, or VAMP7...
  2. Gordon D, Chia J, Jayawardena K, Antrobus R, Bard F, Peden A. VAMP3/Syb and YKT6 are required for the fusion of constitutive secretory carriers with the plasma membrane. PLoS Genet. 2017;13:e1006698 pubmed publisher
    ..RNAi mediated depletion of YKT6 and VAMP3 in mammalian cells also blocks constitutive secretion suggesting that YKT6 has an evolutionarily conserved role in ..
  3. Park S, Kang J, Lee J, Vo T, Kim H. Application of Physical and Chemical Enhanced Backwashing to Reduce Membrane Fouling in the Water Treatment Process Using Ceramic Membranes. Membranes (Basel). 2018;8: pubmed publisher
    ..investigated the improvement of operating efficiency through physical cleaning and chemical enhanced backwashing (CEB) using ceramic membranes with high permeability and chemical safety compared to organic membranes...
  4. Kristensen M, Schmidt S, Kibsgaard L, Mogensen M, Sommerlund M, Koppelhus U. Validity of first-time diagnoses of congenital epidermolysis bullosa in the Danish National Patient Registry and the Danish Pathology Registry. Clin Epidemiol. 2019;11:115-124 pubmed publisher
    Congenital epidermolysis bullosa (CEB) is a group of rare monogenic genodermatoses. Phenotypically, the diseases vary in both severity and dissemination, which complicates studies of their epidemiology...
  5. Puri C, Renna M, Bento C, Moreau K, Rubinsztein D. Diverse autophagosome membrane sources coalesce in recycling endosomes. Cell. 2013;154:1285-99 pubmed publisher
    ..mATG9- and ATG16L1-containing vesicles traffic to recycling endosomes, where VAMP3-dependent heterotypic fusions occur...
  6. Jin Z, Gong H, Wang K. Application of hybrid coagulation microfiltration with air backflushing to direct sewage concentration for organic matter recovery. J Hazard Mater. 2015;283:824-31 pubmed publisher
    ..Compared to Direct Membrane Filtration (DMF) with Chemically Enhanced Backwash (CEB), HCM with AB achieved better concentration efficiency with higher concentration extent and concentration velocity ..
  7. Sadler J, Bryant N, Gould G. Characterization of VAMP isoforms in 3T3-L1 adipocytes: implications for GLUT4 trafficking. Mol Biol Cell. 2015;26:530-6 pubmed publisher
    ..of Syntaxin4 and SNAP23, and whereas many studies identify VAMP2 as the v-SNARE, others suggest that either VAMP3 or VAMP8 may also fulfil this role...
  8. Van Ngo H, Bhalla M, Chen D, Ireton K. A role for host cell exocytosis in InlB-mediated internalisation of Listeria monocytogenes. Cell Microbiol. 2017;19: pubmed publisher
    ..Using a probe consisting of VAMP3 with an exofacial green fluorescent protein tag, focal exocytosis was detected during InlB-mediated entry...
  9. Kimura K, Uchida H. Intensive membrane cleaning for MBRs equipped with flat-sheet ceramic membranes: Controlling negative effects of chemical reagents used for membrane cleaning. Water Res. 2019;150:21-28 pubmed publisher
    ..Circulation of granular materials (cylindrical polyurethane) in the tank and frequent chemically enhanced backwash (CEB) were used as intensive physical cleaning and chemical cleaning in this study, respectively...
  10. Yousefzadeh M, Zhu Y, McGowan S, Angelini L, Fuhrmann Stroissnigg H, Xu M, et al. Fisetin is a senotherapeutic that extends health and lifespan. EBioMedicine. 2018;36:18-28 pubmed publisher
    ..Subcore, JLK), a Glenn Foundation/American Federation for Aging Research (AFAR) BIG Award (JLK), Glenn/AFAR (LJN, CEB), the Ted Nash Long Life and Noaber Foundations (JLK), the Connor Group (JLK), Robert J. and Theresa W...
  11. Keith J, Rapgay L, Theodore D, Schwartz J, Ross J. An assessment of an automated EEG biofeedback system for attention deficits in a substance use disorders residential treatment setting. Psychol Addict Behav. 2015;29:17-25 pubmed publisher
    ..either received 15 sessions of automated EEG biofeedback (AEB), 15 sessions of clinician guided EEG biofeedback (CEB), or 15 additional therapy sessions (AT)...
  12. Kaspar K, Howell A, Khoo C. A randomized, double-blind, placebo-controlled trial to assess the bacterial anti-adhesion effects of cranberry extract beverages. Food Funct. 2015;6:1212-7 pubmed publisher
    ..In the pilot study, subjects consumed a cranberry extract beverage (CEB) or a cranberry extract and juice beverage (CEJB), compared to placebo...
  13. Zhu S, Bhat S, Syan S, Kuchitsu Y, Fukuda M, Zurzolo C. Rab11a-Rab8a cascade regulates the formation of tunneling nanotubes through vesicle recycling. J Cell Sci. 2018;131: pubmed publisher
    ..We demonstrate that these two Rab GTPases act in a cascade in which Rab11a activation of Rab8a is independent of Rabin8. We also show that VAMP3 acts downstream of Rab8a to regulate TNT formation.
  14. Breher Esch S, Sahini N, Trincone A, Wallstab C, Borlak J. Genomics of lipid-laden human hepatocyte cultures enables drug target screening for the treatment of non-alcoholic fatty liver disease. BMC Med Genomics. 2018;11:111 pubmed publisher effector C (CIDEC), perilipins (PLIN2, PLIN3), the synaptosome-associated-protein 23 and the vesicle associated membrane protein 3 were strongly up-regulated...
  15. Zhang H, Yu J, Yang L, Kramer L, Zhang X, Na W, et al. Identification of genome-wide SNP-SNP interactions associated with important traits in chicken. BMC Genomics. 2017;18:892 pubmed publisher
    ..Three genes on GGA21 (SDHB, PARK7 and VAMP3) and nine genes (AGTPBP1, CAMK4, CDC14B, FANCC, FBP1, GNAQ, PTCH1, ROR2 and STARD4) on GGAZ that might be ..
  16. Schreck D, Fishberg R. Detection of acute myocardial ischemic injury by gender using a novel cardiac electrical biomarker. Am J Emerg Med. 2015;33:383-90 pubmed publisher
    The objective of this study us to stratify by gender a new cardiac electrical biomarker (CEB) diagnostic accuracy for detection of acute myocardial ischemic injury (AMII)...
  17. Barber M, Arai Y, Morishita Y, Vigier L, Causeret F, Borello U, et al. Migration Speed of Cajal-Retzius Cells Modulated by Vesicular Trafficking Controls the Size of Higher-Order Cortical Areas. Curr Biol. 2015;25:2466-78 pubmed publisher
    ..CR migration speed is cell autonomously modulated by vesicle-associated membrane protein 3 (VAMP3), a classically non-neuronal mediator of endosomal recycling...
  18. Jenny Zhou H, Qin L, Zhang H, Tang W, Ji W, He Y, et al. Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation. Nat Med. 2016;22:1033-1042 pubmed publisher CCM disease progression, we found that CCM3 suppresses UNC13B- and vesicle-associated membrane protein 3 (VAMP3)-dependent exocytosis of angiopoietin 2 (ANGPT2) in brain endothelial cells...
  19. Schaefer A, Bochenek G, Jochens A, Ellinghaus D, Dommisch H, Güzeldemir Akçakanat E, et al. Genetic evidence for PLASMINOGEN as a shared genetic risk factor of coronary artery disease and periodontitis. Circ Cardiovasc Genet. 2015;8:159-67 pubmed publisher
    Genetic studies demonstrated the presence of risk alleles in the genes ANRIL and CAMTA1/VAMP3 that are shared between coronary artery disease (CAD) and periodontitis...
  20. Prekeris R, Yang B, Oorschot V, Klumperman J, Scheller R. Differential roles of syntaxin 7 and syntaxin 8 in endosomal trafficking. Mol Biol Cell. 1999;10:3891-908 pubmed
    ..Although several SNAREs, including VAMP3/cellubrevin, VAMP8/endobrevin, syntaxin 13, and syntaxin 7, have been localized to the endosomal membranes, their precise ..
  21. Kaminski C, Rees E, Schierle G. A quantitative protocol for intensity-based live cell FRET imaging. Methods Mol Biol. 2014;1076:445-54 pubmed publisher
    ..We also provide a software program that automates the calibration tasks outlined in this protocol and which is available for free to download ( ).
  22. Cai W, Liu J, Zhang X, Ng W, Liu Y. Generation of dissolved organic matter and byproducts from activated sludge during contact with sodium hypochlorite and its implications to on-line chemical cleaning in MBR. Water Res. 2016;104:44-52 pubmed publisher
    ..of on-line chemical cleaning in MBR such as chemical cleaning-in-place (CIP) and chemical enhanced backwash (CEB), little information is currently available for the release of emerging dissolved organic matter (DOM) and ..
  23. Vashi N, Andrabi S, Ghanwat S, Suar M, Kumar D. Ca2+-dependent Focal Exocytosis of Golgi-derived Vesicles Helps Phagocytic Uptake in Macrophages. J Biol Chem. 2017;292:5144-5165 pubmed publisher
    ..was an early event mediated by focal exocytosis and coincided with the recruitment of transferrin receptor, VAMP3, and dynamin-2...
  24. Althubiti M, Lezina L, Carrera S, Jukes Jones R, Giblett S, Antonov A, et al. Characterization of novel markers of senescence and their prognostic potential in cancer. Cell Death Dis. 2014;5:e1528 pubmed publisher
    ..107 proteins that could be potential markers of senescence and validated 10 of them (DEP1, NTAL, EBP50, STX4, VAMP3, ARMX3, B2MG, LANCL1, VPS26A and PLD3)...
  25. Zhang Y, Zhao X, Zhang X, Sun J. The influence of chemically enhanced backwash by-products (CEBBPs) on water quality in the coagulation-ultrafiltration process. Environ Sci Pollut Res Int. 2016;23:1805-19 pubmed publisher
    ..typical types of chemically enhanced backwash by-products (CEBBPs) produced in the chemically enhanced backwash (CEB) process and the influence of CEB parameters on typical CEBBPs in the coagulation-ultrafiltration process...
  26. Barile M, Pisitkun T, Yu M, Chou C, Verbalis M, Shen R, et al. Large scale protein identification in intracellular aquaporin-2 vesicles from renal inner medullary collecting duct. Mol Cell Proteomics. 2005;4:1095-106 pubmed
    ..These results show that AQP2-containing vesicles are heterogeneous and that intracellular AQP2 resides chiefly in endosomes, trans-Golgi network, and rough endoplasmic reticulum. ..
  27. Li R, Scanlon K, May A, Rose C, Birch L. Bottle-feeding practices during early infancy and eating behaviors at 6 years of age. Pediatrics. 2014;134 Suppl 1:S70-7 pubmed publisher examines associations of bottle-feeding practices during infancy with MFS and children's eating behavior (CEB) at 6 years old...
  28. Hayashi K, Sasai M, Iwasaki A. Toll-like receptor 9 trafficking and signaling for type I interferons requires PIKfyve activity. Int Immunol. 2015;27:435-45 pubmed publisher
    ..Signaling from these TLRs bifurcate at the level of distinct endosomal compartments, namely VAMP3(+) and LAMP(+) endosomes, to mediate the induction of cytokine and type I interferon (IFN) genes, respectively...
  29. Ara E, Sartaj M, Kennedy K. Enhanced biogas production by anaerobic co-digestion from a trinary mix substrate over a binary mix substrate. Waste Manag Res. 2015;33:578-87 pubmed publisher
    ..5, and 140% higher than the calculated expected biogas (CEB) yield from the corresponding individual substrates. The trinary mixture of OFMSW:TWAS:PS at ratios of 25:37.5:375...
  30. Chai M, Zhu X, Cui H, Jiang C, Zhang J, Shi L. Lily Cultivars Have Allelopathic Potential in Controlling Orobanche aegyptiaca Persoon. PLoS ONE. 2015;10:e0142811 pubmed publisher
    ..lily cultivars (Lilium Oriental hybrids 'Sorbonne', Lilium LA (Longiflorum hybrids x Asiatic hybrids) hybrids 'Ceb Dazzle', and Lilium Longiflorum hybrids (L. formosanum x L. longiflorum) 'L. formolongo') to induce O...
  31. Moreau K, Fleming A, Imarisio S, Lopez Ramirez A, Mercer J, Jimenez Sanchez M, et al. PICALM modulates autophagy activity and tau accumulation. Nat Commun. 2014;5:4998 pubmed publisher
    ..CALM influences autophagy by regulating the endocytosis of SNAREs, such as VAMP2, VAMP3 and VAMP8, which have diverse effects on different stages of the autophagy pathway, from autophagosome formation ..
  32. Carney K, Milanese M, Van Nierop P, Li K, Oliet S, Smit A, et al. Proteomic analysis of gliosomes from mouse brain: identification and investigation of glial membrane proteins. J Proteome Res. 2014;13:5918-27 pubmed publisher
    ..gliosome preparations were found to be enriched for different classes of known astrocyte proteins, such as VAMP3 (involved in astrocyte exocytosis), Ezrin (perisynaptic astrocyte cytoskeletal protein), and Basigin (astrocyte ..
  33. Clancy J, Sedgwick A, Rosse C, Muralidharan Chari V, Raposo G, Method M, et al. Regulated delivery of molecular cargo to invasive tumour-derived microvesicles. Nat Commun. 2015;6:6919 pubmed publisher
    ..Here we demonstrate that in amoeboid-like invasive tumour cell lines, the v-SNARE, VAMP3, regulates delivery of microvesicle cargo such as the membrane-type 1 matrix metalloprotease (MT1-MMP) to shedding ..
  34. Alizadeh F, Heydari S, Nejadgashti R. Effectiveness of caudal epidural block on interaoperative blood loss during hypospadias repair: A randomized clinical trial. J Pediatr Urol. 2018;: pubmed publisher
    ..Some studies have demonstrated the utility of caudal epidural block (CEB) in this regard among pediatric patients with hypospadias...
  35. Renard H, Garcia Castillo M, Chambon V, Lamaze C, Johannes L. Shiga toxin stimulates clathrin-independent endocytosis of the VAMP2, VAMP3 and VAMP8 SNARE proteins. J Cell Sci. 2015;128:2891-902 pubmed publisher
    ..The SNARE proteins VAMP2, VAMP3 and VAMP8 are internalized in a clathrin-dependent manner...
  36. Farag M, Khalifa A, Elhadidy W, Rashad R. Hepatorenal protection in renal ischemia/reperfusion by celecoxib and pentoxifylline. J Surg Res. 2016;204:183-91 pubmed publisher
    ..This study was performed to evaluate the effects of celecoxib (CEB) and pentoxifylline (PTX) on kidney and liver changes after renal I/R in rats...
  37. Sethi N, Pant D, Dutta A, Koul A, Sood J, Chugh P. Comparison of caudal epidural block and ultrasonography-guided transversus abdominis plane block for pain relief in children undergoing lower abdominal surgery. J Clin Anesth. 2016;33:322-9 pubmed publisher
    We conducted this study to compare the efficacy of caudal epidural block (CEB) vs ultrasonography-guided transversus abdominis plane (TAP) block for providing postoperative pain relief in children scheduled for lower abdominal surgery...
  38. Caronni N, Simoncello F, Stafetta F, Guarnaccia C, Ruiz Moreno J, Opitz B, et al. Downregulation of Membrane Trafficking Proteins and Lactate Conditioning Determine Loss of Dendritic Cell Function in Lung Cancer. Cancer Res. 2018;78:1685-1699 pubmed publisher
    ..Tumor-conditioned DC exhibited downregulation of the SNARE VAMP3, a regulator of endosomes trafficking critical for cross-presentation of tumor antigens and DC-mediated tumor ..
  39. Caceres P, Mendez M, Haque M, Ortiz P. Vesicle-associated Membrane Protein 3 (VAMP3) Mediates Constitutive Trafficking of the Renal Co-transporter NKCC2 in Thick Ascending Limbs: ROLE IN RENAL FUNCTION AND BLOOD PRESSURE. J Biol Chem. 2016;291:22063-22073 pubmed
    ..Here we report that NKCC2 interacts with the vesicle fusion protein VAMP3, and they co-localize at the TAL apical surface...
  40. Saini C, Petrenko V, Pulimeno P, Giovannoni L, Berney T, Hebrok M, et al. A functional circadian clock is required for proper insulin secretion by human pancreatic islet cells. Diabetes Obes Metab. 2016;18:355-65 pubmed publisher
    ..secretion pathway (GNAQ, ATP1A1, ATP5G2, KCNJ11) and transcripts required for granule maturation and release (VAMP3, STX6, SLC30A8) were affected...
  41. Zhu J, LIU Y, Zhang Y, Zhao C, Yao W, Li Y, et al. VAMP3 and SNAP23 mediate the disturbed flow-induced endothelial microRNA secretion and smooth muscle hyperplasia. Proc Natl Acad Sci U S A. 2017;114:8271-8276 pubmed publisher
    ..miR-126-3p and other microRNAs (miRNAs) via the activation of SNAREs, vesicle-associated membrane protein 3 (VAMP3) and synaptosomal-associated protein 23 (SNAP23)...
  42. Chew B, Mathison B, Kimble L, McKay D, Kaspar K, Khoo C, et al. Chronic consumption of a low calorie, high polyphenol cranberry beverage attenuates inflammation and improves glucoregulation and HDL cholesterol in healthy overweight humans: a randomized controlled trial. Eur J Nutr. 2018;: pubmed publisher
    ..5) consumed 450 mL placebo or low calorie, high polyphenol cranberry extract beverage (CEB) daily for 8 week in a randomized, double-blind, placebo-controlled, parallel design trial...
  43. Wang Y, Yu Y, Luan Y, An J, Yin D, Zhang X. Bioactivation of 1-chloro-2-hydroxy-3-butene, an in vitro metabolite of 1,3-butadiene, by rat liver microsomes. Chem Biol Interact. 2018;282:36-44 pubmed publisher
    ..The results showed that CHB was converted to 1-chloro-3,4-epoxy-2-butanol (CEB) and CBO...
  44. Martín Ávila A, Medina Tamayo J, Ibarra Sanchez A, Vázquez Victorio G, Castillo Arellano J, Hernández Mondragón A, et al. Protein Tyrosine Kinase Fyn Regulates TLR4-Elicited Responses on Mast Cells Controlling the Function of a PP2A-PKC?/? Signaling Node Leading to TNF Secretion. J Immunol. 2016;196:5075-88 pubmed publisher
    ..Addition of LPS provoked coalescence of VAMP3 and its interaction with synaptosomal-associated protein 23; those events were increased in the absence of Fyn...
  45. Casgrain P, Martel C, McMaster W, Mottram J, Olivier M, Descoteaux A. Cysteine Peptidase B Regulates Leishmania mexicana Virulence through the Modulation of GP63 Expression. PLoS Pathog. 2016;12:e1005658 pubmed publisher
    ..We initially examined the impact of L. mexicana infection on the trafficking of VAMP3 and VAMP8, two endocytic SNARE proteins associated with phagolysosome biogenesis and function...
  46. Oligny L, Bérubé P, Barbeau B. Impact of PAC Fines in Fouling of Polymeric and Ceramic Low-Pressure Membranes for Drinking Water Treatment. Membranes (Basel). 2016;6: pubmed publisher
    ..were measured following three cleaning procedures: Physical backwashing (BW), chemically enhanced backwashing (CEB) and Clean-in-Place (CIP)...
  47. Lee C, Park C, Choi J, Kim J. Effects of various chemical cleaning conditions for pressured MF process. Water Sci Technol. 2017;75:1063-1070 pubmed publisher
    ..operated under various conditions to assess the relative influence of backwashing, chemical enhanced backwashing (CEB), and bag filter application...
  48. Xu H, Arnold M, Kumar S. Differential Effects of Munc18s on Multiple Degranulation-Relevant Trans-SNARE Complexes. PLoS ONE. 2015;10:e0138683 pubmed publisher
    ..complexes under enhanced tethering conditions: i) VAMP2/syntaxin3/SNAP-23, ii) VAMP2/syntaxin4/SNAP-23, iii) VAMP3/syntaxin3/SNAP-23, iv) VAMP3/syntaxin4/SNAP-23, v) VAMP8/syntaxin3/SNAP-23, and vi) VAMP8/syntaxin4/SNAP-23...
  49. Ropert N, Jalil A, Li D. Expression and cellular function of vSNARE proteins in brain astrocytes. Neuroscience. 2016;323:76-83 pubmed publisher
    ..Astrocytic vesicles expressing VAMP2 and VAMP3 vesicular SNARE (vSNARE) proteins have been suggested to be a key feature of the tripartite synapse and mediate ..
  50. Stenovec M, Lasič E, Božić M, Bobnar S, Stout R, Grubišić V, et al. Ketamine Inhibits ATP-Evoked Exocytotic Release of Brain-Derived Neurotrophic Factor from Vesicles in Cultured Rat Astrocytes. Mol Neurobiol. 2016;53:6882-6896 pubmed
    ..fusion protein attachment protein receptor (SNARE) proteins, vesicle-associated membrane protein 2 (VAMP2), VAMP3, and synaptotagmin IV...
  51. Mei X, Quek P, Wang Z, Ng H. Alkali-assisted membrane cleaning for fouling control of anaerobic ceramic membrane bioreactor. Bioresour Technol. 2017;240:25-32 pubmed publisher
    In this study, a chemically enhanced backflush (CEB) cleaning method using NaOH solution was proposed for fouling mitigation in anaerobic membrane bioreactors (AnMBRs). Ex-situ cleaning tests revealed that NaOH dosages ranging from 0...
  52. Li J, Zhou R, Bie B, Huang N, Guo Y, Chen H, et al. Emodin and baicalein inhibit sodium taurocholate-induced vacuole formation in pancreatic acinar cells. World J Gastroenterol. 2018;24:35-45 pubmed publisher
    To investigate the effects of combined use of emodin and baicalein (CEB) at the cellular and organism levels in severe acute pancreatitis (SAP) and explore the underlying mechanism...
  53. Annaert W, Becker B, Kistner U, Reth M, Jahn R. Export of cellubrevin from the endoplasmic reticulum is controlled by BAP31. J Cell Biol. 1997;139:1397-410 pubmed
    b>Cellubrevin is a ubiquitously expressed membrane protein that is localized to endosomes throughout the endocytotic pathway and functions in constitutive exocytosis...
  54. Ganley I, Espinosa E, Pfeffer S. A syntaxin 10-SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells. J Cell Biol. 2008;180:159-72 pubmed publisher
    ..that a soluble NSF attachment protein receptor (SNARE) complex comprised of syntaxin 10 (STX10), STX16, Vti1a, and VAMP3 is required for this MPR transport but not for the STX6-dependent transport of TGN46 or cholera toxin from early ..
  55. Shi C, Li N, Dong J, Wang L, Li X, Ji C, et al. Association between maternal nonresponsive feeding practice and child's eating behavior and weight status: children aged 1 to 6 years. Eur J Pediatr. 2017;176:1603-1612 pubmed publisher
    ..this study are to investigate the prevalence of nonresponsive feeding practice (NRFP) and child's eating behavior (CEB) and to explore the hypothetical association between child's weight status, NRFP and CEB for 1- to 6-year-old ..
  56. Schlosser A, Aldekamp T, Schrempf H. Binding characteristics of CebR, the regulator of the ceb operon required for cellobiose/cellotriose uptake in Streptomyces reticuli. FEMS Microbiol Lett. 2000;190:127-32 pubmed
    ..cellulose to cellooligomers, cellobiose and cellotriose which are taken up by mycelia via an ABC transport system (Ceb) induced during growth with cellobiose or cellulose...
  57. Uechi Y, Bayarjargal M, Umikawa M, Oshiro M, Takei K, Yamashiro Y, et al. Rap2 function requires palmitoylation and recycling endosome localization. Biochem Biophys Res Commun. 2009;378:732-7 pubmed publisher
    ..These observations implicate the involvement of palmitoylation and recycling endosome localization in cellular functions of Rap2 proteins. ..
  58. Bagheri H, Govsa F. Anatomy of the sacral hiatus and its clinical relevance in caudal epidural block. Surg Radiol Anat. 2017;39:943-951 pubmed publisher
    Caudal epidural anesthesia (CEB) is widely used for the prevention of chronic lower back pain, the control of intraoperative analgesia such as genitourinary surgery and labor pain cases in sacral epidural space approach for the ..
  59. Polgar J, Chung S, Reed G. Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion. Blood. 2002;100:1081-3 pubmed
    ..In contrast, rVAMP-2, which formed SNARE complexes in vitro, had no effect on platelet exocytosis. We conclude that VAMP-3 and VAMP-8 form SNARE complexes with platelet syntaxin 4 and are required for platelet granule secretion. ..
  60. Mazzolini J, Herit F, Bouchet J, Benmerah A, Benichou S, Niedergang F. Inhibition of phagocytosis in HIV-1-infected macrophages relies on Nef-dependent alteration of focal delivery of recycling compartments. Blood. 2010;115:4226-36 pubmed publisher
    ..Finally, an alteration of the recruitment of vesicle-associated membrane protein (VAMP3)- and tumor necrosis factor-alpha (TNFalpha)-positive recycling endosomes regulated by AP1, but not of VAMP7-..
  61. Bochenek G, Häsler R, El Mokhtari N, Konig I, Loos B, Jepsen S, et al. The large non-coding RNA ANRIL, which is associated with atherosclerosis, periodontitis and several forms of cancer, regulates ADIPOR1, VAMP3 and C11ORF10. Hum Mol Genet. 2013;22:4516-27 pubmed publisher
    ..By genome-wide expression profiling using Affymetrix HG1.0 ST Arrays, we identified the transcription of ADIPOR1, VAMP3 and C11ORF10 to be correlated with decreased ANRIL expression in a time-dependent manner...
  62. Zhang X, Jiang S, Mitok K, Li L, Attie A, Martin T. BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cells. J Cell Biol. 2017;216:2151-2166 pubmed publisher
    ..Ca2+ rises that stimulate DCV exocytosis may stimulate BAIAP3-dependent retrograde trafficking to maintain DCV protein homeostasis and DCV function. ..
  63. Schwarz Y, Zhao N, Kirchhoff F, Bruns D. Astrocytes control synaptic strength by two distinct v-SNARE-dependent release pathways. Nat Neurosci. 2017;20:1529-1539 pubmed publisher
    ..Here we report that astrocytes express synaptobrevin II and cellubrevin as functionally non-overlapping vesicular SNARE proteins on glutamatergic vesicles and neuropeptide Y-..
  64. Boal F, Zhang H, Tessier C, Scotti P, Lang J. The variable C-terminus of cysteine string proteins modulates exocytosis and protein-protein interactions. Biochemistry. 2004;43:16212-23 pubmed
    ..The interaction is isoform specific as recombinant Csp1 binds VAMP1 and VAMP7, but not VAMP3. Cross-linking in permeabilized clonal beta-cells revealed homodimerization of Csp which is stimulated by Ca(2+) ..
  65. Luftman K, Hasan N, Day P, Hardee D, Hu C. Silencing of VAMP3 inhibits cell migration and integrin-mediated adhesion. Biochem Biophys Res Commun. 2009;380:65-70 pubmed publisher
    ..In the present study, we examined the roles of VAMP3, a SNARE protein that mediates exocytosis, in cell migration and integrin trafficking...
  66. Jovic M, Kean M, Dubankova A, Boura E, Gingras A, Brill J, et al. Endosomal sorting of VAMP3 is regulated by PI4K2A. J Cell Sci. 2014;127:3745-56 pubmed publisher
    ..phosphatidylinositol 4-kinase II? (PI4K2A) as a binding partner of vesicle-associated membrane protein 3 (VAMP3), a small R-SNARE involved in recycling and retrograde transport, and found that the two proteins co-reside on ..
  67. Combes A, Camosseto V, N Guessan P, Argüello R, Mussard J, Caux C, et al. BAD-LAMP controls TLR9 trafficking and signalling in human plasmacytoid dendritic cells. Nat Commun. 2017;8:913 pubmed publisher
    ..An inducible VAMP3+/LAMP2+/LAMP1- endolysosome compartment exists in pDCs from which TLR9 activation ..
  68. Riento K, Galli T, Jansson S, Ehnholm C, Lehtonen E, Olkkonen V. Interaction of Munc-18-2 with syntaxin 3 controls the association of apical SNAREs in epithelial cells. J Cell Sci. 1998;111 ( Pt 17):2681-8 pubmed
    ..Munc-18-2 bound to syntaxin 3 by overexpression results in a marked decrease in the SNARE proteins SNAP-23 and cellubrevin bound to the syntaxin...
  69. Freedman S, Song H, Xu Y, Sun Z, Eck M. Homotetrameric structure of the SNAP-23 N-terminal coiled-coil domain. J Biol Chem. 2003;278:13462-7 pubmed
    ..A comparison of the SNAP-23N structure to other SNARE complex structures reveals how a simple coiled-coil motif can form diverse SNARE complexes. ..
  70. Okumura A, Hatsuzawa K, Tamura T, Nagaya H, Saeki K, Okumura F, et al. Involvement of a novel Q-SNARE, D12, in quality control of the endomembrane system. J Biol Chem. 2006;281:4495-506 pubmed
    ..This unexpected observation was supported by evidence that D12 associates with VAMP7, a SNARE in the endosomal-lysosomal pathway. Hence, we suggest that D12 participates in the degradative function of lysosomes. ..
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    ..Previous experiments using antibodies to synaptobrevin/vesicle associated membrane protein (VAMP) 1, 2, or rat cellubrevin failed to detect these v-SNAREs in human platelets, although membrane proteins from these cells could support ..
  72. Wade N, Bryant N, Connolly L, Simpson R, Luzio J, Piper R, et al. Syntaxin 7 complexes with mouse Vps10p tail interactor 1b, syntaxin 6, vesicle-associated membrane protein (VAMP)8, and VAMP7 in b16 melanoma cells. J Biol Chem. 2001;276:19820-7 pubmed
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    ..Taken together, these findings indicate that ACAP1 promotes cargo sorting by recognizing recycling sorting signals. ..
  74. Abou Jamra R, Gobina C, Becker T, Georgi A, Schulze T, Schmael C, et al. Association study between genetic variants at the VAMP2 and VAMP3 loci and bipolar affective disorder. Psychiatr Genet. 2008;18:199-203 pubmed publisher
    Vesicle-associated membrane proteins 2 and 3 (VAMP2 and VAMP3) are required for the release of D-serine, a competitive agonist of the neurotransmitter glycine at the glutamatergic N-methyl-D-aspartate receptors...
  75. Rahman A, Decourcey J, Larbi N, Loughran S, Walls D, Loscher C. Syntaxin-4 is essential for IgE secretion by plasma cells. Biochem Biophys Res Commun. 2013;440:163-7 pubmed publisher
    ..An understanding of this machinery may be beneficial in identifying potential therapeutic targets in multiple myeloma and autoimmune disease where over-production of Ig leads to severe pathology in patients. ..
  76. Ligeon L, Moreau K, Barois N, Bongiovanni A, Lacorre D, Werkmeister E, et al. Role of VAMP3 and VAMP7 in the commitment of Yersinia pseudotuberculosis to LC3-associated pathways involving single- or double-membrane vacuoles. Autophagy. 2014;10:1588-602 pubmed publisher
    ..Second, in these cells, we unexpectedly found that VAMP3 localizes preferentially to Yersinia-containing vacuoles (YCVs) with single membranes using correlative light-..
  77. Verboogen D, González Mancha N, ter Beest M, van den Bogaart G. Fluorescence Lifetime Imaging Microscopy reveals rerouting of SNARE trafficking driving dendritic cell activation. elife. 2017;6: pubmed publisher
    ..dendritic cells by bacterial lipopolysaccharide leads to increased FRET of fluorescently labeled syntaxin 4 with VAMP3 specifically at the plasma membrane, indicating increased SNARE complex formation, whereas FRET with other tested ..
  78. Breton S, Nsumu N, Galli T, Sabolic I, Smith P, Brown D. Tetanus toxin-mediated cleavage of cellubrevin inhibits proton secretion in the male reproductive tract. Am J Physiol Renal Physiol. 2000;278:F717-25 pubmed
    ..b>Cellubrevin, an analog of the vesicle soluble N-ethyl malemide-sensitive factor attachment protein (SNAP) receptor (v-SNARE)..
  79. Demishev S, Krasnorussky V, Bogach A, Voronov V, Shitsevalova N, Filipov V, et al. Electron nematic effect induced by magnetic field in antiferroquadrupole phase of CeB 6. Sci Rep. 2017;7:17430 pubmed publisher
    ..of the angular dependences of the magnetoresistance in the orbitally ordered antiferroquadrupole (AFQ) phase of CeB6...
  80. Poschet J, Skidmore J, Boucher J, Firoved A, Van Dyke R, Deretic V. Hyperacidification of cellubrevin endocytic compartments and defective endosomal recycling in cystic fibrosis respiratory epithelial cells. J Biol Chem. 2002;277:13959-65 pubmed
    ..ratiometric imaging with luminally exposed pH-sensitive green fluorescent protein, that CFTR affects the pH of cellubrevin-labeled endosomal organelles resulting in hyperacidification of these compartments in cystic fibrosis lung ..
  81. Vassilopoulos S, Esk C, Hoshino S, Funke B, Chen C, Plocik A, et al. A role for the CHC22 clathrin heavy-chain isoform in human glucose metabolism. Science. 2009;324:1192-6 pubmed publisher
    ..Thus, CHC22-dependent membrane trafficking constitutes a species-restricted pathway in human muscle and fat with potential implications for type 2 diabetes. ..
  82. Fader C, Sánchez D, Mestre M, Colombo M. TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways. Biochim Biophys Acta. 2009;1793:1901-16 pubmed publisher
    ..SNAREs are key molecules of the vesicle fusion machinery. TI-VAMP/VAMP7 and VAMP3/cellubrevin are two v-SNARE proteins involved in the endocytic and exocytic pathways...
  83. Pulido I, Jahn R, Gerke V. VAMP3 is associated with endothelial weibel-palade bodies and participates in their Ca(2+)-dependent exocytosis. Biochim Biophys Acta. 2011;1813:1038-44 pubmed publisher
    ..This indicates that endothelial cells specifically select VAMP 3 over VAMP8 to cooperate with syntaxin 4 and SNAP23 in the Ca(2+)-triggered fusion of WPB with the plasma membrane...
  84. Finetti F, Patrussi L, Galgano D, Cassioli C, Perinetti G, Pazour G, et al. The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse. J Cell Sci. 2015;128:2541-52 pubmed publisher
    ..The results identify Rab8 as a new player in vesicular traffic to the immune synapse and provide insight into the pathways co-opted by different cell types for immune synapse assembly and ciliogenesis. ..
  85. Vogel G, Klee K, Janecke A, Müller T, Hess M, Huber L. Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3. J Cell Biol. 2015;211:587-604 pubmed publisher
    ..Hence, our work demonstrates how Myo5B, Stx3, Slp4a, Vamp7, Munc18-2, and Rab8/11 cooperate during selective apical cargo trafficking and exocytosis in epithelial cells and thereby provides further insight into MVID pathophysiology. ..
  86. Schlattner U, Klaus A, Ramírez Ríos S, Guzun R, Kay L, Tokarska Schlattner M. Cellular compartmentation of energy metabolism: creatine kinase microcompartments and recruitment of B-type creatine kinase to specific subcellular sites. Amino Acids. 2016;48:1751-74 pubmed publisher
    ..2) yeast-two-hybrid analysis using cytosolic split-protein assays and the identifying membrane proteins VAMP2, VAMP3 and JWA as putative BCK interaction partners; and (3) phosphorylation experiments, showing that the cellular ..
  87. Timmers K, Clark A, Omatsu Kanbe M, Whiteheart S, Bennett M, Holman G, et al. Identification of SNAP receptors in rat adipose cell membrane fractions and in SNARE complexes co-immunoprecipitated with epitope-tagged N-ethylmaleimide-sensitive fusion protein. Biochem J. 1996;320 ( Pt 2):429-36 pubmed
    ..Biol. Chem. 267, 11681-11684] have been identified as synaptobrevin 2 (VAMP 2) and cellubrevin (VAMP 3) by using isoform-specific antisera...
  88. Riggs K, Hasan N, Humphrey D, Raleigh C, Nevitt C, Corbin D, et al. Regulation of integrin endocytic recycling and chemotactic cell migration by syntaxin 6 and VAMP3 interaction. J Cell Sci. 2012;125:3827-39 pubmed publisher
    ..In STX6-depleted cells, ?3?1 integrin is accumulated in recycling endosomes that contain the v-SNARE VAMP3. Importantly, we show that STX6 and VAMP3 form a v-/t-SNARE complex, VAMP3 is required in ?3?1 integrin delivery ..
  89. Nair Gupta P, Baccarini A, Tung N, Seyffer F, Florey O, Huang Y, et al. TLR signals induce phagosomal MHC-I delivery from the endosomal recycling compartment to allow cross-presentation. Cell. 2014;158:506-21 pubmed publisher
    ..Instead, MHC-I are recruited from an endosomal recycling compartment (ERC), which is marked by Rab11a, VAMP3/cellubrevin, and VAMP8/endobrevin and holds large reserves of MHC-I...
  90. Kawabata A, Serada S, Naka T, Mori Y. Human herpesvirus 6 gM/gN complex interacts with v-SNARE in infected cells. J Gen Virol. 2014;95:2769-77 pubmed publisher
    ..showed that the HHV-6 gM/gN complex interacts with the v-SNARE protein, vesicle-associated membrane protein 3 (VAMP3)...
  91. Kuster A, Nola S, Dingli F, Vacca B, Gauchy C, Beaujouan J, et al. The Q-soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor (Q-SNARE) SNAP-47 Regulates Trafficking of Selected Vesicle-associated Membrane Proteins (VAMPs). J Biol Chem. 2015;290:28056-69 pubmed publisher
    ..We conclude that SNAP-47 plays a role in the proper localization and function of a subset of VAMPs likely via regulation of their transport through the early secretory pathway. ..
  92. Yoshida Y, Yasuda S, Fujita T, Hamasaki M, Murakami A, Kawawaki J, et al. Ubiquitination of exposed glycoproteins by SCFFBXO27 directs damaged lysosomes for autophagy. Proc Natl Acad Sci U S A. 2017;114:8574-8579 pubmed publisher
    ..We also screened for proteins that are ubiquitinated upon lysosomal damage, and identified two SNARE proteins, VAMP3 and VAMP7, and five lysosomal proteins, LAMP1, LAMP2, GNS, PSAP, and TMEM192...