UL33

Summary

Gene Symbol: UL33
Description: interacts with DNA packaging terminase subunit 2; involved in DNA encapsidation
Alias: interacts with DNA packaging terminase subunit 2, involved in DNA encapsidation, DNA packaging protein UL33
Species: Human herpesvirus 2

Top Publications

  1. McGeoch D, Cunningham C, McIntyre G, Dolan A. Comparative sequence analysis of the long repeat regions and adjoining parts of the long unique regions in the genomes of herpes simplex viruses types 1 and 2. J Gen Virol. 1991;72 ( Pt 12):3057-75 pubmed
    ..Properties of the LAT sequences in both HSV-1 and HSV-2 were consistent with LATs being generated as an intron excised from a longer transcript. ..
  2. McGeoch D, Moss H, McNab D, Frame M. DNA sequence and genetic content of the HindIII l region in the short unique component of the herpes simplex virus type 2 genome: identification of the gene encoding glycoprotein G, and evolutionary comparisons. J Gen Virol. 1987;68 ( Pt 1):19-38 pubmed
    ..These data were interpreted to suggest, first, that HSV-2 US4 represents an ancient gene of alpha herpesviruses, and, more tentatively, that the evolution of the genes for gG and gD may have proceeded through a duplication event. ..
  3. Barnett B, Dolan A, Telford E, Davison A, McGeoch D. A novel herpes simplex virus gene (UL49A) encodes a putative membrane protein with counterparts in other herpesviruses. J Gen Virol. 1992;73 ( Pt 8):2167-71 pubmed publisher
    ..Therefore, we consider that this ORF represents an additional HSV gene (UL49A) with counterparts in all sequenced alpha-, beta- and gammaherpesviruses...
  4. Kolb A, Larsen I, Cuellar J, Brandt C. Genomic, phylogenetic, and recombinational characterization of herpes simplex virus 2 strains. J Virol. 2015;89:6427-34 pubmed publisher
  5. Everett R, Fenwick M. Comparative DNA sequence analysis of the host shutoff genes of different strains of herpes simplex virus: type 2 strain HG52 encodes a truncated UL41 product. J Gen Virol. 1990;71 ( Pt 6):1387-90 pubmed publisher
    ..The results show that the UL41 genes of strains G and 17 are 86% homologous and that the lack of shutoff by HG52 is likely to be explained by a frameshift mutation within its UL41 coding sequence...

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