TRA@

Summary

Gene Symbol: TRA@
Description: T cell receptor alpha locus
Alias: TCRA, TCRD, TRA, T-cell antigen receptor, alpha polypeptide, T-cell receptor, alpha (V,D,J,C)
Species: human

Top Publications

  1. ncbi Feedforward responses of transversus abdominis are directionally specific and act asymmetrically: implications for core stability theories
    Garry T Allison
    School of Physiotherapy, Curtin University, Perth, Western Australia, Australia
    J Orthop Sports Phys Ther 38:228-37. 2008
  2. ncbi Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids
    Y H Ding
    Department of Molecular and Cellular Biology, Harvard University, Howard Hughes Medical Institute, Cambridge, Massachusetts 02138, USA
    Immunity 8:403-11. 1998
  3. ncbi New mechanisms of hormone secretion: MDR-like gene products as extrusion pumps for hormones?
    K F Becker
    Department of Physiology, University of Munich, Germany
    Horm Metab Res 24:210-3. 1992
  4. ncbi [Diagnostic value of transesophageal echocardiography in traumatic rupture of the thoracic aorta]
    P Vignon
    , CHU Dupuytren
    Arch Mal Coeur Vaiss 87:767-73. 1994
  5. ncbi A genetic analysis of the sex-determining gene, tra-1, in the nematode Caenorhabditis elegans
    J Hodgkin
    MRC Laboratory of Molecular Biology, Cambridge, UK
    Genes Dev 1:731-45. 1987
  6. ncbi Genetic analysis of the Enterococcus vancomycin resistance conjugative plasmid pHTbeta: identification of the region involved in cell aggregation and traB, a key regulator gene for plasmid transfer and cell aggregation
    Haruyoshi Tomita
    Department of Bacteriology, Gunma University Graduate School of Medicine, Maebashi, Gunma 371 8511, Japan
    J Bacteriol 190:7739-53. 2008
  7. ncbi A genomic island present along the bacterial chromosome of the Parachlamydiaceae UWE25, an obligate amoebal endosymbiont, encodes a potentially functional F-like conjugative DNA transfer system
    Gilbert Greub
    Center for Research on Intracellular Bacteria, Institute of Microbiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland
    BMC Microbiol 4:48. 2004
  8. ncbi [Plasmid profiles of aminoglycoside-resistant Pseudomonas aeruginosa]
    K Tsukada
    Department of Surgery 1, Gunma University, School of Medicine
    Kansenshogaku Zasshi 64:202-9. 1990
  9. ncbi Distinct regulatory programs establish widespread sex-specific alternative splicing in Drosophila melanogaster
    Britta Hartmann
    Centre de Regulacio Genomica, Barcelona, Spain
    RNA 17:453-68. 2011
  10. ncbi Identification and characterization of a new conjugation/type IVA secretion system (trb/tra) of Legionella pneumophila Corby localized on two mobile genomic islands
    Gernot Glockner
    Leibniz Institute for Age Research Fritz Lipmann Institute, D 07745 Jena, Germany
    Int J Med Microbiol 298:411-28. 2008

Detail Information

Publications166 found, 100 shown here

  1. ncbi Feedforward responses of transversus abdominis are directionally specific and act asymmetrically: implications for core stability theories
    Garry T Allison
    School of Physiotherapy, Curtin University, Perth, Western Australia, Australia
    J Orthop Sports Phys Ther 38:228-37. 2008
    ..Experimental laboratory study supplemented with a repeated case study...
  2. ncbi Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids
    Y H Ding
    Department of Molecular and Cellular Biology, Harvard University, Howard Hughes Medical Institute, Cambridge, Massachusetts 02138, USA
    Immunity 8:403-11. 1998
    ..The existence of a structurally similar diagonal binding mode for TCRs favors mechanisms based on the formation of geometrically defined supramolecular assemblies for initiating signaling...
  3. ncbi New mechanisms of hormone secretion: MDR-like gene products as extrusion pumps for hormones?
    K F Becker
    Department of Physiology, University of Munich, Germany
    Horm Metab Res 24:210-3. 1992
    ..High amounts of NG-TRA mRNA are found in a variety of human brain tumors...
  4. ncbi [Diagnostic value of transesophageal echocardiography in traumatic rupture of the thoracic aorta]
    P Vignon
    , CHU Dupuytren
    Arch Mal Coeur Vaiss 87:767-73. 1994
    ..Echocardiographic diagnosis of TRA is based on the recording of the association of a thick and mobile intraluminal echo corresponding to the torn ..
  5. ncbi A genetic analysis of the sex-determining gene, tra-1, in the nematode Caenorhabditis elegans
    J Hodgkin
    MRC Laboratory of Molecular Biology, Cambridge, UK
    Genes Dev 1:731-45. 1987
    ..The autosomal gene tra-1 is a major switch gene controlling sexual phenotype...
  6. ncbi Genetic analysis of the Enterococcus vancomycin resistance conjugative plasmid pHTbeta: identification of the region involved in cell aggregation and traB, a key regulator gene for plasmid transfer and cell aggregation
    Haruyoshi Tomita
    Department of Bacteriology, Gunma University Graduate School of Medicine, Maebashi, Gunma 371 8511, Japan
    J Bacteriol 190:7739-53. 2008
    ..The transfer-related regions (Tra I, Tra II, and Tra III) containing oriT and a putative nickase gene (traI) have previously been identified in ..
  7. ncbi A genomic island present along the bacterial chromosome of the Parachlamydiaceae UWE25, an obligate amoebal endosymbiont, encodes a potentially functional F-like conjugative DNA transfer system
    Gilbert Greub
    Center for Research on Intracellular Bacteria, Institute of Microbiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland
    BMC Microbiol 4:48. 2004
    ..The genome of Protochlamydia amoebophila UWE25, a Parachlamydia-related endosymbiont of free-living amoebae, was recently published, providing the opportunity to search for genomic islands (GIs)...
  8. ncbi [Plasmid profiles of aminoglycoside-resistant Pseudomonas aeruginosa]
    K Tsukada
    Department of Surgery 1, Gunma University, School of Medicine
    Kansenshogaku Zasshi 64:202-9. 1990
    ..2) A strain of I-serotype and Hh8-phage type containing the plasmid I (GM-SM-SA-PIPC, Tra-, 22.6Kb or 22...
  9. ncbi Distinct regulatory programs establish widespread sex-specific alternative splicing in Drosophila melanogaster
    Britta Hartmann
    Centre de Regulacio Genomica, Barcelona, Spain
    RNA 17:453-68. 2011
    ..Bioinformatic analysis of SXL/TRA binding sites, experimental analysis of sex-specific splicing in S2 and Kc cells lines and of the effects of SXL ..
  10. ncbi Identification and characterization of a new conjugation/type IVA secretion system (trb/tra) of Legionella pneumophila Corby localized on two mobile genomic islands
    Gernot Glockner
    Leibniz Institute for Age Research Fritz Lipmann Institute, D 07745 Jena, Germany
    Int J Med Microbiol 298:411-28. 2008
    ..In this study we identified and analysed a new type of conjugation/type IVA secretion system (trb/tra) of L. pneumophila Corby, a virulent human isolate...
  11. ncbi Widespread expression of a new putative hormone extrusion pump: NG-TRA transporter protein in human and rat tissue
    M Ristow
    , Bochum, Germany
    Horm Metab Res 28:138-41. 1996
    ..To gain further insight into its significance we studied the expression of NG-TRA in human and rat tissues and compared the nucleotide sequences derived from both species using reverse transcription ..
  12. ncbi Lymphoid differentiation pathways can be traced by TCR delta rearrangements
    Eva Fronkova
    Childhood Leukemia Investigation Prague, Czech Republic
    J Immunol 175:2495-500. 2005
    ..Ig genes are rearranged in B cells using the same enzyme machinery. TCRD (TCR delta) genes are frequently incompletely rearranged in B precursor leukemias and recently were found in a ..
  13. ncbi Sex determination in the germ line of Drosophila depends on genetic signals and inductive somatic factors
    R Nothiger
    Zoological Institute, University of Zurich, Switzerland
    Development 107:505-18. 1989
    ..and 2X:3A were sexually transformed into pseudomales by mutations at the sex-determining genes Sxl (Sex-lethal), tra (transformer), tra-2 (transformer-2), or dsx (double-sex)...
  14. ncbi Traumatic rupture of thoracic aorta in real-world motor vehicle crashes
    Samuel Bertrand
    Laboratoire d Automatique, de Mécanique et d Informatique Industrielles et Humaines LAMIH, Universite de Valenciennes et du Hainaut Cambresis, Valenciennes, France samuel
    Traffic Inj Prev 9:153-61. 2008
    ..This study aims at evaluating the most relevant risk factors of TRA. It also aims at analyzing the types of TRA as a function of car crash conditions and rib cage fractures.
  15. ncbi Specific Taenia crassiceps and Taenia solium antigenic peptides for neurocysticercosis immunodiagnosis using serum samples
    E C Bueno
    Laboratory of Clinical Immunology, Faculty of Pharmaceutical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil
    J Clin Microbiol 38:146-51. 2000
    ..by enzyme-linked immunosorbent assay (ELISA) and by immunoblotting with Taenia crassiceps vesicular fluid antigen (Tcra) and Taenia solium total saline antigen (Tso) for the detection of immunoglobulin G antibodies...
  16. ncbi Comparison of tretinoin 0.05% cream and 3% alcohol-based salicylic acid preparation in the treatment of acne vulgaris
    L Babayeva
    Faculty of Medicine, Department of Dermatology, Dokuz Eylul University, Izmir, Turkey
    J Eur Acad Dermatol Venereol 25:328-33. 2011
    ..Salicylic acid (SA), tretinoin (all-TRA) and clindamycin phosphate (CDP) are known to to be effective agents depending on their comedolytic and anti-..
  17. ncbi Recovering probabilities for nucleotide trimming processes for T cell receptor TRA and TRG V-J junctions analyzed with IMGT tools
    Kevin Bleakley
    Institut Curie, Centre de Recherche, Paris, F 75248, France
    BMC Bioinformatics 9:408. 2008
    ..However, as trimmed nucleotides can potentially be replaced by identical N region nucleotides during the process, the observed "output" represents a biased estimate of the "true trimming process."..
  18. ncbi Liarozole markedly increases all trans-retinoic acid toxicity in mouse limb bud cell cultures: a model to explain the potency of the aromatic retinoid (E)-4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylenyl)-1-propenyl] benzoic acid
    Michael A Pignatello
    Laboratory of Cellular and Biochemical Toxicology, Rutgers University, Piscataway, New Jersey 08854, USA
    Toxicol Appl Pharmacol 178:186-94. 2002
    ..half-life in retinoid toxicity, experiments were performed to determine whether, and to what extent, inhibition of tRA metabolism by liarozole increased its toxicity comparable to that of TTNPB in the mouse limb bud system...
  19. ncbi Predicting the contribution of rat cytochrome P-450 3A1, 3A2 and human cytochrome P-450 3A4, 3A5 to territrem a 4beta-C hydroxylation using the relative activity factor
    Yu Husan Lin
    Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan, Republic of China
    J Toxicol Environ Health A 71:1407-14. 2008
    ..In liver microsomes from five male Wistar rats, TRA 4beta-C hydroxylation activity significantly correlated with CYP3A1/2 activity, while, in liver microsomes from ..
  20. ncbi TRA-418, a novel compound having both thromboxane A(2) receptor antagonistic and prostaglandin I(2) receptor agonistic activities: its antiplatelet effects in human and animal platelets
    N Yamada
    Clinical Development Center, Toray Industries, Inc, Urayasu, Chiba, Japan
    J Thromb Haemost 1:1813-9. 2003
    b>TRA-418 is a novel compound that has been found in our screening for compounds having both thromboxane A2 (TP) receptor antagonistic and prostaglandin I2 (IP) receptor agonistic activities...
  21. ncbi Inhibition of proliferation and induction of apoptosis in soft tissue sarcoma cells by interferon-alpha and retinoids
    T Brodowicz
    Clinical Division of Oncology, Department of Medicine I, University Hospital, Vienna, Australia
    Br J Cancer 80:1350-8. 1999
    ..Similarly, 9cRA, 13cRA and tRA decreased the proliferation of HTB-82 and HTB-93 STS cells, whereas the proliferation of p53-mutated HTB-91, HTB-92 ..
  22. ncbi Production and characterization of monoclonal antibodies specific to pangasius catfish, basa, and tra
    K G Gajewski
    Department of Nutrition, Food and Exercise Sciences, Florida State Univ, Tallahassee, FL 32306 1493, USA
    J Food Sci 74:C241-7. 2009
    ..MAb T7E10 recognized 2 antigenic proteins (molecular weight approximately 36 and 75 kDa) in raw and cooked tra and basa extracts, while T1G11 bound to several proteins (molecular weight between 13 and 18 kDa) in tra and basa ..
  23. ncbi Activity of the Agrobacterium Ti plasmid conjugal transfer regulator TraR is inhibited by the product of the traM gene
    C Fuqua
    Section of Microbiology, Cornell University, Ithaca, New York 14853
    J Bacteriol 177:1367-73. 1995
    The Agrobacterium Ti plasmid tra regulon was previously found to be positively regulated by the TraR protein in the presence of a diffusible N-acyl homoserine lactone designated Agrobacterium autoinducer (AAI)...
  24. ncbi Effect of the gene transformer of Anastrepha on the somatic sexual development of Drosophila
    Maria Fernanda Ruiz
    Centro de Investigaciones Biologicas CSIC, Madrid, Spain
    Int J Dev Biol 54:627-33. 2010
    ..The transformer cDNA of Anastrepha encoding the putative full-length Tra protein was cloned in pUAST and introduced into Drosophila melanogaster...
  25. ncbi Our experience with transradial approach for coronary angiography
    Veli Vefali
    Department of Cardiology, Cankaya Hospital, Ankara, Turkey
    Turk Kardiyol Dern Ars 36:163-7. 2008
    Transradial approach (TRA) for coronary angiography has only become popular in our country in recent years. In this study, we evaluated radial and femoral angiographies performed at our center.
  26. ncbi Arbitrary shaped, liquid filled reverberators with non-resonant transducers for broadband focusing of ultrasound using Time Reversed Acoustics
    A Sarvazyan
    Artann Laboratories, 1753 Linvale Harbourton Road, Trenton, NJ 08530, USA
    Ultrasonics 49:301-5. 2009
    ..an alternative technique of ultrasound focusing based on the principles of Time Reversed Acoustics (TRA) because in TRA systems, effective focusing can be achieved with just a few, or even one, transducers...
  27. ncbi Tissue residue approach for chemical mixtures
    Scott Dyer
    Procter and Gamble, 11810 East Miami River Road, Cincinnati, Ohio 45201, USA
    Integr Environ Assess Manag 7:99-115. 2011
    ..This article reviews the literature related to the TRA for mixtures of chemicals and recommends a practical, tiered approach that can be implemented in regulatory or risk ..
  28. ncbi Endogenous distribution of retinoids during normal development and teratogenesis in the mouse embryo
    C Horton
    Developmental Biology Research Centre, King s College London, United Kingdom
    Dev Dyn 202:312-23. 1995
    ..The levels of tRA do not change significantly over the 6 days of development analysed, whereas t-retinol rises sharply as the liver ..
  29. ncbi Antiproliferative effects of trapidil in vascular smooth muscle cells are associated by inhibition of MAPK and P34(cdc2) activity
    Y Cheng
    Institute of Clinical Pharmacology, Tongji Medical University, Wuhan, People s Republic of China
    J Cardiovasc Pharmacol 35:1-6. 2000
    Trapidil (Tra) is a potent coronary vasodilator. Recent studies have shown that Tra possesses antiproliferative activity in glioma cells and vascular smooth muscle cells (VSMCs)...
  30. ncbi The conjugal transfer system of Agrobacterium tumefaciens octopine-type Ti plasmids is closely related to the transfer system of an IncP plasmid and distantly related to Ti plasmid vir genes
    J Alt-Mörbe
    Institut fur Biologie III, Universitat Freiburg, Germany
    J Bacteriol 178:4248-57. 1996
    ..Both regions previously were shown to contain sequences that hybridize with tra genes of the nopaline-type Ti plasmid pTiC58...
  31. ncbi The tra region of the nopaline-type Ti plasmid is a chimera with elements related to the transfer systems of RSF1010, RP4, and F
    S K Farrand
    Department of Crop Sciences, University of Illinois at Urbana Champaign, 61801, USA
    J Bacteriol 178:4233-47. 1996
    ..The determinants responsible for conjugal transfer map to two regions, tra and trb, of the nopaline-type Ti plasmid pTiC58...
  32. ncbi A rehabilitative ultrasound imaging investigation of lateral abdominal muscle thickness in healthy aging adults
    Deborah M Stetts
    Department of Physical Therapy Education, Elon University, Elon, NC 27244 2010, USA
    J Geriatr Phys Ther 32:60-6. 2009
    ..The purpose of this study was to investigate, using RUSI, the size and symmetry of the lateral abdominal muscles bilaterally at rest and during the ADIM in healthy older adults and the reliability of these measurements...
  33. ncbi Using the theory of reasoned action to determine physicians' intention to measure body mass index in children and adolescents
    Rahul Khanna
    Department of Pharmaceutical Systems and Policy, West Virginia University, PO Box 9510, Morgantown, WV 26506 9510, USA
    Res Social Adm Pharm 5:170-81. 2009
    ..However, studies have shown that physicians infrequently measure BMI in children and adolescents...
  34. ncbi Differential activity of regions of transversus abdominis during trunk rotation
    Donna M Urquhart
    Department of Physiotherapy, The University of Melbourne, Melbourne, Victoria, Australia
    Eur Spine J 14:393-400. 2005
    ..middle region of TrA, obliquus internus abdominis (OI) and obliquus externus abdominis (OE), and lower region of TrA and OI. Surface electrodes were placed over right rectus abdominis (RA)...
  35. ncbi FOG-2, a novel F-box containing protein, associates with the GLD-1 RNA binding protein and directs male sex determination in the C. elegans hermaphrodite germline
    R Clifford
    Department of Genetics, Washington University School of Medicine, Campus Box 8232, St Louis, MO 63110, USA
    Development 127:5265-76. 2000
    Male sex determination in the Caenorhabditis elegans hermaphrodite germline requires translational repression of tra-2 mRNA by the GLD-1 RNA binding protein...
  36. ncbi [Ketorolac versus tramadol: comparative study of analgesic efficacy in the postoperative pain in abdominal hysterectomy]
    G Ollé Fortuny
    Servicio de Anestesiologia y Reanimacion, Hospital de Mataro, Consorci Hospitalari del Maresme, Mataro, Barcelona
    Rev Esp Anestesiol Reanim 47:162-7. 2000
    ..To compare the analgesic efficacy of tramadol to that of ketorolac trometamol administered intravenously and at fixed times over the 24 hours after abdominal hysterectomy...
  37. ncbi Differential control of abdominal muscles during multi-directional support-surface translations in man
    Mark G Carpenter
    School of Human Kinetics, University of British Columbia, Vancouver, BC, Canada
    Exp Brain Res 188:445-55. 2008
    ..on translation direction within the first 100 ms of activity, whereas responses from the two deeper muscles (TrA and OI) were independent of translation direction during this interval...
  38. ncbi The TRA-1-60 and TRA-1-81 human pluripotent stem cell markers are expressed on podocalyxin in embryonal carcinoma
    William M Schopperle
    Department of Surgery, Beth Israel Deaconess Medical Center, RW 875, 330 Brookline Ave, Boston, MA 02215, USA
    Stem Cells 25:723-30. 2007
    ..Embryonal carcinoma, as do all human pluripotent stem cells, expresses TRA-1-60 and TRA-1-81 antigens, and although their molecular identities are unknown, they are commonly used as markers ..
  39. ncbi Time-effect profile of antihypertensive agents assessed with trough/peak ratio, smoothness index and dose omission: an ambulatory blood pressure monitoring study with trandolapril vs. quinapril
    Anca Radauceanu
    Centre d Investigation Clinique CIC, INSERM CHU de Nancy, France
    Fundam Clin Pharmacol 16:545-54. 2002
    ..Group T/P were 0.85 for Tra and 0.62 for Qui...
  40. ncbi Targeted removal of PML-RARalpha protein is required prior to inhibition of histone deacetylase for overcoming all-trans retinoic acid differentiation resistance in acute promyelocytic leukemia
    Yongkui Jing
    Division of Medical Oncology, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029 6547, USA
    Blood 100:1008-13. 2002
    ..Treatment with tRA in tRA differentiation-resistant NB4 subclones R4 and MR-2 does not result in PML-RARalpha diminution and the tested ..
  41. ncbi Comparative histologic effects of daily topical application of creams containing all-trans-retinoic acid or all-trans-retinoyl beta-glucuronide on pig skin
    Desiree B Gunning
    Departments of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa 50011, USA
    Skin Pharmacol Appl Skin Physiol 15:205-12. 2002
    ..However, whereas 3.3 mM tRA shows side effects, 3.3 mM RAG does not...
  42. ncbi Determination and kinetics of enrofloxacin and ciprofloxacin in Tra catfish (Pangasianodon hypophthalmus) and giant freshwater prawn (Macrobrachium rosenbergii) using a liquid chromatography/mass spectrometry method
    S Danyi
    Department of Food Sciences, Laboratory of Food Analysis, Faculty of Veterinary Medicine, CART Center for Analytical Research and Technology, University of Liege, B 4000 Liege, Belgium
    J Vet Pharmacol Ther 34:142-52. 2011
    Determination and kinetics of enrofloxacin and ciprofloxacin in Tra catfish (Pangasianodon hypophthalmus) and giant freshwater prawn (Macrobrachium rosenbergii) using a liquid chromatography/mass spectrometry method. J. vet. Pharmacol...
  43. ncbi Tensile transmission across the lumbar fasciae in unembalmed cadavers: effects of tension to various muscular attachments
    Priscilla J Barker
    Department of Anatomy and Cell Biology, University of Melbourne, Victoria, Australia
    Spine (Phila Pa 1976) 29:129-38. 2004
    ..Traction was applied to muscles attaching to the posterior and middle layers of lumbar fascia (PLF, MLF). Effects on fasciae were determined via tensile force measures and movement of markers...
  44. ncbi A review of the tissue residue approach for organic and organometallic compounds in aquatic organisms
    Anne E McElroy
    School of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, New York 11794 5000, USA
    Integr Environ Assess Manag 7:50-74. 2011
    ..The vast majority of data available on TRA is derived from laboratory studies of acute lethal responses to organic toxicants exhibiting baseline toxicity...
  45. ncbi Both retinoic acid receptors alpha (RARalpha) and gamma (RARgamma) are able to initiate mouse upper-lip skin glandular metaplasia
    S Blanchet
    Epithelial Differentiation Biology, LEDAC UMR CNRS, Albert Bonniot Institute, La Tronche, France
    J Invest Dermatol 111:206-12. 1998
    ..retinoic acid (tRA) give rise to a glandular metaplasia of hair vibrissa follicles; however, at this concentration, tRA can activate not only the three retinoic acid receptors (RARalpha, beta, and gamma), but also the retinoid X ..
  46. ncbi Comparative study on the sedative effects of morphine, methadone, butorphanol or tramadol, in combination with acepromazine, in dogs
    Eduardo Raposo Monteiro
    Faculty of Veterinary Medicine, Centro Universitário de Maringá CESUMAR, Parana, Brazil
    Vet Anaesth Analg 36:25-33. 2009
    To compare the effects of morphine (MOR), methadone (MET), butorphanol (BUT) and tramadol (TRA), in combination with acepromazine, on sedation, cardiorespiratory variables, body temperature and incidence of emesis in dogs.
  47. ncbi Biochemical and genetic analysis of the OKa blood group antigen
    B P Williams
    Laboratory of Human Molecular Genetics, Imperial Cancer Research Fund, London, UK
    Immunogenetics 27:322-9. 1988
    The monoclonal antibody TRA-1-85 recognizes a cell surface antigen which is expressed by all human cell types tested, including red blood cells (RBCs), but not by mouse cells...
  48. ncbi Glycan stem-cell markers are specifically expressed by spermatogonia in the adult non-human primate testis
    T Muller
    Stem Cell Research Group, German Primate Center, Kellnerweg 4, 37077 Gottingen, Germany
    Hum Reprod 23:2292-8. 2008
    The glycan cell surface molecules, stage-specific embryonic antigen (SSEA)-1, -3 and -4 and tumor-rejection antigen (TRA)-1-60 and -1-81, are expressed in specific combinations by undifferentiated pluripotent cells, i.e...
  49. ncbi A magnetic resonance imaging investigation of the transversus abdominis muscle during drawing-in of the abdominal wall in elite Australian Football League players with and without low back pain
    Julie A Hides
    Division of Physiotherapy, School of Health and Rehabilitation Sciences, University of Queensland, Brisbane, Australia
    J Orthop Sports Phys Ther 40:4-10. 2010
    ..Single-blinded quasi-experimental study...
  50. ncbi Altered response of the anterolateral abdominal muscles to simulated weight-bearing in subjects with low back pain
    Julie A Hides
    Division of Physiotherapy, School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, QLD, 4072, Australia
    Eur Spine J 18:410-8. 2009
    ..Real-time ultrasound imaging was used to assess changes in thickness of the TrA and internal oblique IO muscles as well as lateral movement ("slide") of the anterior fascial insertion of ..
  51. ncbi Regulation of doublesex pre-mRNA processing occurs by 3'-splice site activation
    L C Ryner
    Department of Biological Sciences, Stanford University, California 94305
    Genes Dev 5:2071-85. 1991
    ..Here, we used transient expression of dsx pre-mRNAs in the presence or absence of tra and tra-2 gene products in Drosophila tissue culture cells to investigate the molecular mechanism controlling this ..
  52. ncbi Feasibility and safety of transradial arterial approach for simultaneous right and left vertebral artery angiographic studies and stenting
    Hon Kan Yip
    Division of Cardiology, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University Collage of Medicine, Kaohsiung, Taiwan, ROC
    Cardiovasc Intervent Radiol 30:840-6. 2007
    This study investigated whether the transradial artery (TRA) approach using a 6-French (F) Kimny guiding catheter for right vertebral artery (VA) angiographic study and stenting is safe and effective for patients with significant VA ..
  53. ncbi Instructing pelvic floor contraction facilitates transversus abdominis thickness increase during low-abdominal hollowing
    Duncan Critchley
    Division of Physiotherapy, Guy s, King s and St Thomas School of Biomedical Sciences, King s College, London, UK
    Physiother Res Int 7:65-75. 2002
    ..The present study investigated the effect of instructing PF contraction on TrA thickness increase during low abdominal hollowing.
  54. ncbi Implementation of the standard strategy for identification of Ig/TCR targets for minimal residual disease diagnostics in B-cell precursor ALL pediatric patients: Polish experience
    Małgorzata Dawidowska
    Department of Molecular and Clinical Genetics, Institute of Human Genetics, Polish Academy of Sciences, Strzeszynska 32, 60 479 Poznan, Poland
    Arch Immunol Ther Exp (Warsz) 56:409-18. 2008
    ..A feasibility study is presented of the standard strategy for the identification of Ig/TCR targets for MRD diagnostics in Polish ALL patients by identifying Ig/TCR gene rearrangement pattern using standard primer sets and protocols...
  55. ncbi Management of traumatic rupture of the thoracic aorta in pediatric patients
    Riyad Karmy-Jones
    Division of Cardiothoracic Trauma, Harborview Medical Center, University of Washington, Seattle, Washington 98104, USA
    Ann Thorac Surg 75:1513-7. 2003
    Traumatic rupture of the thoracic aorta (TRA) in the pediatric population is uncommon. Management of TRA in general has evolved to include selective nonoperative and endovascular stent graft approaches, although operative repair remains ..
  56. ncbi Retinoic acid inhibits induction of c-Jun protein by ultraviolet radiation that occurs subsequent to activation of mitogen-activated protein kinase pathways in human skin in vivo
    G J Fisher
    Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan 48109 0609, USA
    J Clin Invest 101:1432-40. 1998
    ..We investigated upstream signal transduction pathways and the mechanism of tRA inhibition of UV induction of matrix metalloproteinases in human skin in vivo...
  57. ncbi Characterization of lateral abdominal muscle thickness in persons with lower extremity amputations
    Barbara A Springer
    Physical Therapy Service, Department of Orthopaedics and Rehabilitation, Walter Reed Army Medical Center, Washington, DC, USA
    J Orthop Sports Phys Ther 37:635-43. 2007
    ..Retrospective review...
  58. ncbi T-cell receptor gamma and delta gene rearrangements and junctional region characteristics in south Indian patients with T-cell acute lymphoblastic leukemia
    Natarajan Sudhakar
    Department of Molecular Oncology, Cancer Institute WIA, Adyar, Chennai, Tamil Nadu, India
    Am J Hematol 82:215-21. 2007
    ..At least one clonal TCRG or TCRD rearrangement was detected in 34 (85%) cases. TCR gamma (TCRG) rearrangement was detected in 25 (62...
  59. ncbi Neurocysticercosis: detection of IgG, IgA and IgE antibodies in cerebrospinal fluid, serum and saliva samples by ELISA with Taenia solium and Taenia crassiceps antigens
    E C Bueno
    Faculty of Pharmaceutical Sciences FPS, University of Sao Paulo USP, Sao Paulo, Brazil
    Arq Neuropsiquiatr 58:18-24. 2000
    ..control group and individuals with other parasitoses, by ELISA with Taenia crassiceps vesicular fluid antigen (Tcra) and Taenia solium total antigen (Tso) for the detection of antibodies...
  60. ncbi Regulation of bacterial conjugation in microaerobiosis by host-encoded functions ArcAB and sdhABCD
    Ana Serna
    Departamento de Genetica, Facultad de Biologia, Universidad de Sevilla, Seville, Spain
    Genetics 184:947-58. 2010
    ..In turn, succinate dehydrogenase (SdhABCD) is a repressor of mating in aerobiosis. ArcA binds upstream of the main tra promoter (p(traY)) and activates tra transcription, as previously described in F, R1, and R100...
  61. ncbi Multiple factors contribute to the toxicity of the aromatic retinoid TTNPB (Ro 13-7410): interactions with the retinoic acid receptors
    M A Pignatello
    Laboratory of Cellular and Biochemical Toxicology, Rutgers University, Piscataway, New Jersey 08854, USA
    Toxicol Appl Pharmacol 159:109-16. 1999
    ..These observations are consistent with the 10-fold lower affinity of TTNPB vs tRA for RARs and, therefore, do not explain the greater potency of TTNPB...
  62. ncbi Driving plasticity in the motor cortex in recurrent low back pain
    Henry Tsao
    NHMRC Centre of Clinical Research Excellence in Spinal Pain, Injury and Health, School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia
    Eur J Pain 14:832-9. 2010
    ..Electromyographic (EMG) activity was recorded from TrA bilaterally using intramuscular fine-wire electrodes...
  63. ncbi Comparative genomic analysis and evolution of the T cell receptor loci in the opossum Monodelphis domestica
    Zuly E Parra
    Center for Evolutionary and Theoretical Immunology and Department of Biology, University of New Mexico, Albuquerque, NM 87131, USA
    BMC Genomics 9:111. 2008
    All jawed-vertebrates have four T cell receptor (TCR) chains: alpha (TRA), beta (TRB), gamma (TRG) and delta (TRD). Marsupials appear unique by having an additional TCR: mu (TRM)...
  64. ncbi Derivation of three clones from human embryonic stem cell lines by FACS sorting and their characterization
    Kuldip S Sidhu
    Stem Cell Group, Diabetes Transplant Unit, Prince of Wales Hospital and University of New South Wales, Sydney, NSW 2031 Australia
    Stem Cells Dev 15:61-9. 2006
    ..e., SSEA3, SSEA4, OCT4, TRA-1-60, and TRA-1-81), and gene expression for pluripotency (Oct-4 and nanog)...
  65. ncbi Trial of the Trachoma Rapid Assessment methodology in The Gambia
    H Limburg
    International Centre for Eye Health, Institute of Ophthalmology, University College London, London, UK
    Ophthalmic Epidemiol 8:73-85. 2001
    To test the validity and repeatability of a newly designed Trachoma Rapid Assessment (TRA) methodology.
  66. ncbi Histopathologic changes of the radial artery wall secondary to transradial catheterization
    Cezar S Staniloae
    Saint Vincent s Hospital Manhattan, New York, NY 10011, USA
    Vasc Health Risk Manag 5:527-32. 2009
    ..The immediate effects of transradial access on the radial artery wall are unknown. In this study we sought to assess the histological changes induced by catheterization on the radial artery...
  67. ncbi Analysis of the conjugal transfer system of the pheromone-independent highly transferable Enterococcus plasmid pMG1: identification of a tra gene (traA) up-regulated during conjugation
    Koichi Tanimoto
    Department of Microbiology, Gunma University School of Medicine, Maebashi, Gunma 371 8511, Japan
    J Bacteriol 184:5800-4. 2002
    ..To analyze regulation of tra gene expression in pMG1, transcripts of pMG1 were examined during conjugation...
  68. ncbi Identification and characterization of the sex-determiner transformer-2 homologue in Chinese shrimp, Fenneropenaeus chinensis
    S Li
    Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, PR China
    Sex Dev 6:267-78. 2012
    The transformer-2 gene, encoding a protein (Tra-2) which directs sex-specifically alternative splicing of doublesex (dsx) pre-mRNA in combination with the transformer (Tra) protein, has been proved to play important roles on sex ..
  69. ncbi Basal LAT-diacylglycerol-RasGRP1 signals in T cells maintain TCRα gene expression
    Evan Markegard
    Department of Anatomy, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 6:e25540. 2011
    ..We postulate that basal LAT-diacylglycerol-RasGRP signals fulfill a regulatory function in peripheral T lymphocytes by maintaining proper gene expression programs...
  70. ncbi Dual combination therapy targeting DR5 and EMMPRIN in pancreatic adenocarcinoma
    Hyunki Kim
    Department of Radiology, University of Alabama at Birmingham, 1670 University Blvd, Birmingham, AL 35294, USA
    Mol Cancer Ther 11:405-15. 2012
    ..Cytotoxicity of anti-EMMPRIN antibody and anti-DR5 antibody (TRA-8) in MIA PaCa-2 and PANC-1 cell lines was measured by ATPlite assay in vitro. The distributions of Cy5...
  71. ncbi Tetracycline-associated transcriptional regulation of transfer genes of the Bacteroides conjugative transposon CTnDOT
    Robert T Jeters
    Department of Microbiology, 601 S Goodwin Ave, Rm B103, University of Illinois, Urbana, IL 61801
    J Bacteriol 191:6374-82. 2009
    ..Reverse transcription-PCR analysis of the region containing the tra genes showed that these genes are regulated at the transcriptional level...
  72. ncbi The sex determination locus transformer-2 of Drosophila encodes a polypeptide with similarity to RNA binding proteins
    T J Goralski
    Department of Biological Sciences, Stanford University, California 94305
    Cell 56:1011-8. 1989
    The D. melanogaster transformer-2 (tra-2) gene regulates somatic sexual differentiation in females and is necessary for spermatogenesis in males...
  73. ncbi The STAR protein QKI-6 is a translational repressor
    L Saccomanno
    Department of Cell Biology, Northwestern University Medical School, Chicago, IL 60611, USA
    Proc Natl Acad Sci U S A 96:12605-10. 1999
    ..Recently, GLD-1 was found to be a translational repressor that acts through regulatory elements, called TGEs (for tra-2 and GLI elements), present in the 3' untranslated region of the sex-determining gene tra-2...
  74. ncbi Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo
    Y Jing
    Department of Medicine, Division of Medical Oncology, Mount Sinai School of Medicine, New York, NY 10029 6547, USA
    Blood 97:264-9. 2001
    ..this study examined the effect of As(2)O(3) on tRA-induced differentiation and, conversely, the effect of tRA on As(2)O(3)-induced apoptosis. As(2)O(3) at subapoptotic concentrations (0...
  75. ncbi A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR
    Kwok S Wun
    Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics, Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria, Australia
    J Exp Med 205:939-49. 2008
    ..Accordingly, although the structural footprint at the NKT TCR-CD1d-alpha-GalCer is small, the energetic footprint is smaller still, and reveals the minimal requirements for CD1d restriction...
  76. ncbi The TRA-1 transcription factor binds TRA-2 to regulate sexual fates in Caenorhabditis elegans
    S Wang
    Department of Biochemistry, University of Wisconsin Madison and Howard Hughes Medical Institute, 53706 1544, USA
    EMBO J 20:1363-72. 2001
    The tra-1 and tra-2 sex-determining genes promote female fates in Caenorhabditis elegans. Classical genetic studies placed tra-1 as the terminal regulator of the pathway with tra-2 acting upstream as a regulator of regulators of tra-1...
  77. ncbi T cell receptor genotyping and HOXA/TLX1 expression define three T lymphoblastic lymphoma subsets which might affect clinical outcome
    Frederic Baleydier
    INSERM EMI0210, and Universite Paris V, Hopital Necker Enfants Malades, Assistance Publique Hopitaux de Paris AP HP, Paris, France
    Clin Cancer Res 14:692-700. 2008
    ..T lymphoblastic lymphomas (T-LBL) are rare disorders of immature T cells which predominantly involve the mediastinum. Their oncogenic pathways and prognostic variables are not clear...
  78. ncbi The gene transformer of anastrepha fruit flies (Diptera, tephritidae) and its evolution in insects
    Maria Fernanda Ruiz
    Centro de Investigaciones Biologicas CSIC, Madrid, Spain
    PLoS ONE 2:e1239. 2007
    ..gene transformer acts as the memory device for sex determination, via an auto-regulatory function; and functional Tra protein is produced only in females...
  79. ncbi TRA-418, a thromboxane A2 receptor antagonist and prostacyclin receptor agonist, inhibits platelet-leukocyte interaction in human whole blood
    Mitsuko Miyamoto
    Pharmaceutical Research Laboratories, Toray Industries, Kamakura, Japan
    Thromb Haemost 104:788-95. 2010
    b>TRA-418, a compound with both thromboxane A2 receptor (TP receptor) antagonistic and prostacyclin receptor (IP receptor) agonistic activities, was synthesised in our laboratory as a new antithrombotic agent...
  80. ncbi A comparison of select trunk muscle thickness change between subjects with low back pain classified in the treatment-based classification system and asymptomatic controls
    Kyle B Kiesel
    Department of Physical Therapy, College of Education and Health Sciences, University of Evansville, WGH 206, Evansville, IN 47722, USA
    J Orthop Sports Phys Ther 37:596-607. 2007
    ..Cross-sectional descriptive...
  81. ncbi Assignment of T cell receptor (TCR) alpha-chain gene (A), beta-chain gene (B), gamma-chain gene (G), and delta-chain gene (D) loci on swine chromosomes by in situ hybridization and radiation hybrid mapping
    H Hiraiwa
    Animal Genome Program Team, STAFF Institute, National Institute of Animal Industry, Tsukuba, Ibaraki 305 0901, Japan
    Cytogenet Cell Genet 93:94-9. 2001
    ..alpha-chain gene (TRA) and the TCR delta-chain gene (TRD) while one clone each carried only the sequence of either TRA or TRD. This observation demonstrated that TRA and TRD are localized in close proximity on a swine chromosome...
  82. ncbi Assessment of abdominal muscle function during a simulated unilateral weight-bearing task using ultrasound imaging
    Julie A Hides
    Division of Physiotherapy, School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia
    J Orthop Sports Phys Ther 37:467-71. 2007
    ..Cross-sectional study...
  83. ncbi Cutting edge: size and diversity of CD4+CD25high Foxp3+ regulatory T cell repertoire in humans: evidence for similarities and partial overlapping with CD4+CD25- T cells
    Nicolas Fazilleau
    Unité de Recherche et d Expertise Immunité anti virale, Biothérapie et Vaccins, Institut National de la Santé et de la Recherche Médicale INSERM U668, Institut Pasteur, France
    J Immunol 179:3412-6. 2007
    ..These data emphasize the intersection between naturally occurring Treg and effector T cell peripheral repertoires and provide new insights into the ontogeny of Treg in humans...
  84. ncbi The potential of a resin-composite to be cured to a 4mm depth
    Garry J P Fleming
    Materials Science Unit, Division of Oral Biosciences, Dublin Dental School and Hospital, Trinity College Dublin, Dublin 2, Ireland
    Dent Mater 24:522-9. 2008
    The potential of a recently marketed resin-based composite (RBC), namely X-tra fil (shade A3), which claims to be amenable to curing to a depth of 4mm was investigated.
  85. ncbi Pre T-cell receptor alpha (pTalpha) expression patterns and functional analysis in human T-cell lymphoblastic leukemia
    Philipp Ivanyi
    Clinic of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Medizinische Hochschule Hannover, Hannover, Germany
    Cell Oncol 32:101-8. 2010
    ..The pTalpha/preTCR regulates the beta-selection, a crucial T-cell developmental checkpoint, providing a most potent survival advantage to thymocytes mediated by the src-kinase p56(Lck)...
  86. ncbi Autoregulation of transformer-2 alternative splicing is necessary for normal male fertility in Drosophila
    M E McGuffin
    Department of Molecular Genetics, The University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Genetics 149:1477-86. 1998
    ..Autoregulation of TRA-2 splicing results in production of two mRNAs that differ by the splicing/retention of the M1 intron and encode ..
  87. ncbi A sensitized genetic background reveals evolution near the terminus of the Caenorhabditis germline sex determination pathway
    Robin Cook Hill
    Department of Biology, University of Maryland, College Park, MD 20742, USA
    Evol Dev 11:333-42. 2009
    ..FEM-1, FEM-2, and FEM-3 specify male fates by promoting proteolysis of the male-repressing transcription factor, TRA-1...
  88. ncbi The chromosomal location of T-cell receptor genes and a T cell rearranging gene: possible correlation with specific translocations in human T cell leukaemia
    T H Rabbitts
    EMBO J 4:1461-5. 1985
    ..The locations of the three different genes, which undergo rearrangement in T cells, may correlate with the chromosomal breakpoints known to be involved in translocations within abnormal human T cells...
  89. ncbi Effect of TRA-8 anti-death receptor 5 antibody in combination with chemotherapy in an ex vivo human ovarian cancer model
    Peter J Frederick
    Division of Gynecologic Oncology, Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, AL, USA
    Int J Gynecol Cancer 19:814-9. 2009
    To investigate the cytotoxicity of TRA-8, an antibody that specifically binds death receptor 5, alone and in combination with chemotherapy, using an ex vivo human ovarian cancer model.
  90. ncbi Diversity of T-cell receptor gene rearrangements in South Indian patients with common acute lymphoblastic leukemia
    Natarajan Sudhakar
    Department of Molecular Oncology, Cancer Institute, Chennai, Tamil Nadu, India
    Iran J Immunol 6:141-6. 2009
    ..Precursor-B-ALL is classified mainly into pro-B-ALL, common-ALL and pre-B-ALL. The Common Acute Lymphoblastic Antigen CD10 is the marker for common-ALL...
  91. ncbi Ultrasound characteristics of the deep abdominal muscles during the active straight leg raise test
    Deydre S Teyhen
    US Army Baylor University Doctoral Program in Physical Therapy, Ft Sam Houston, TX 78234, USA
    Arch Phys Med Rehabil 90:761-7. 2009
    To determine whether changes in the transversus abdominis (TrA) and internal oblique (IO) muscles, as seen on ultrasound imaging, during the active straight leg raise (ASLR) test differ between subjects with and without unilateral ..
  92. ncbi Polymorphism located in TCRA locus confers susceptibility to essential hypersomnia with HLA-DRB1*1501-DQB1*0602 haplotype
    Taku Miyagawa
    Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, Japan
    J Hum Genet 55:63-5. 2010
    ..Single-nucleotide polymorphism (SNP) rs1154155 located in the T-cell receptor alpha (TCRA) locus has been recently identified as a novel genetic marker of susceptibility for narcolepsy with cataplexy...
  93. ncbi Monoclonal antibody-based sandwich ELISA for reliable identification of imported Pangasius catfish
    Yun Hwa P Hsieh
    Dept of Nutrition, Food and Exercise Sciences, Florida State Univ, Tallahassee, FL 32306 1493, USA
    J Food Sci 74:C602-7. 2009
    ..This sandwich ELISA reliably identified fully cooked basa and tra from more than 70 common finfish, shellfish, land animal species, and other protein materials tested...
  94. ncbi Tumor-specific detection of an optically targeted antibody combined with a quencher-conjugated neutravidin "quencher-chaser": a dual "quench and chase" strategy to improve target to nontarget ratios for molecular imaging of cancer
    Mikako Ogawa
    Molecular Imaging Program, Center for Cancer Research, National Cancer Institute, National Institute of Health, Bethesda, MD 20892 1088, USA
    Bioconjug Chem 20:147-54. 2009
    ..type 2 (HER2), was biotinylated and conjugated with the near-infrared (NIR) fluorophore Alexa680 to synthesize Tra-Alexa680-biotin...
  95. ncbi Germline genomic structure of the B10.A mouse Tcra-V2 gene subfamily
    H Gahery-Segard
    Unite d Immunochimie Analytique, Departement d Immunologie, Institut Pasteur, CNRS UA 359 and Université Pierre et Marie Curie, 75724 Paris Cedex 15, France
    Immunogenetics 44:298-305. 1996
    The number of mouse Tcra-V gene segments varies from one individual to another and is estimated to be about 100...
  96. ncbi An early decrease in Notch activation is required for human TCR-alphabeta lineage differentiation at the expense of TCR-gammadelta T cells
    Inge Van de Walle
    Department of Clinical Chemistry, Microbiology and Immunology, Faculty of Medicine and Health Sciences, Ghent University, Ghent University Hospital, Ghent, Belgium
    Blood 113:2988-98. 2009
    ..Our results reveal stage-dependent molecular changes in Notch signaling that are critical for normal human T-cell development and reveal fundamental molecular differences between mouse and human...
  97. ncbi Suprabasal expression of a dominant-negative RXR alpha mutant in transgenic mouse epidermis impairs regulation of gene transcription and basal keratinocyte proliferation by RAR-selective retinoids
    X Feng
    Department of Dermatology, University of Michigan, Ann Arbor 48109 0314, USA
    Genes Dev 11:59-71. 1997
    ..keratin-10 gene promoter, expression of dnRXR alpha severely reduced the ability of RAR-selective ligands tRA and CD367 to induce epidermal mRNA levels of the CRABPII, CRBPI, and CRBPII genes, which contain RA-responsive ..
  98. ncbi Safety and efficacy of transradial aortoiliac interventions
    Cezar S Staniloae
    Division of Cardiovascular Diseases, Saint Vincent Catholic Medical Center, New York, New York, USA
    Catheter Cardiovasc Interv 75:659-62. 2010
    This study compares transradial approach (TRA) aortoiliac angioplasty/stenting to the transfemoral approach (TFA).
  99. ncbi Synergistic transcriptional activation of the mouse urokinase plasminogen activator (uPA) gene and of its enhancer activator protein 1 (AP1) site by cAMP and retinoic acid
    R Mira-y-Lopez
    Mount Sinai School of Medicine, Department of Medicine, Box 1178, 1 Gustave L Levy Place, New York, NY10029, USA
    Biochem J 331:909-16. 1998
    ..Photoaffinity labelling experiments showed that tRA did not alter the cellular content of cAMP-dependent protein kinase regulatory subunits I and II...

Research Grants68

  1. EID - Effects of avian migration & anthropogenic change on the distribution & tra
    Thomas Smith; Fiscal Year: 2007
    ..Finally, we will share our results with public health organizations and the scientific community in a timely fashion in order to maximize the public good. ..
  2. EID - Effects of avian migration & anthropogenic change on the distribution & tra
    Thomas Smith; Fiscal Year: 2009
    ..Finally, we will share our results with public health organizations and the scientific community in a timely fashion in order to maximize the public good. ..
  3. Quorum Sensing in Sinorhizobium meliloti
    Juan Gonzalez; Fiscal Year: 2009
    ..We have characterized three of those systems (Mel, Sin and Tra) and established that they play a part in nodulation, exopolysaccharide production, nitrogen fixation and conjugal ..
  4. Quorum Sensing in Sinorhizobium meliloti
    Juan Gonzalez; Fiscal Year: 2006
    ..We have characterized three of those systems (Mel, Sin and Tra) and established that they play a part in nodulation, exopolysaccharide production and conjugal plasmid transfer...
  5. PS07-003, Minority HIV/AIDS Research Initiative
    Jose Nanin; Fiscal Year: 2007
    ..the qualitative and quantitative data will be utilized to explore components of the Theory of Reasoned Action (TRA) framework of the study as well as the content and contexts of HIV prevention through interpersonal communication...
  6. Arsenic Trioxide and Acute Myeloid Leukemia
    Yongkui Jing; Fiscal Year: 2005
    ..remission in acute promyelocytic leukemia (APL, AML-M3) patients that relapsed after all trans retinoic acid (tRA) and chemotherapy treatment...
  7. ASSESSMENT OF CLINICAL RETINOID ACTIVITY IN LEUKEMIA
    Robert Gallagher; Fiscal Year: 1993
    ..Specifically, the following parameters will be tested for possible correlations with clinical-outcome and/or tRA responsiveness of APL cells in vitro: (1) three different forms of the t(15;17)-generated PML-RARalpha fusion gene, ..
  8. Alternative processing and antisense regulation of thyroid hormone receptor mRNA
    STEPHEN MUNROE; Fiscal Year: 2007
    ..In mammals the TRa gene produces two alternatively spliced mRNAs that encode two functionally antagonistic transcription factors...
  9. Alcohol and Condom Use Resistance in Sexually Coercive/Violent Men
    Kelly Cue Davis; Fiscal Year: 2010
    ..upon Alcohol Myopia Theory, Alcohol Expectancy Theory, and the Theories of Reasoned Action and Planned Behavior (TRA/TPB), two experiments are proposed to investigate the influence of alcohol [Sober, Placebo (expect ...
  10. Structural MRI of trabecular bone for therapy response monitoring
    Felix Wehrli; Fiscal Year: 2009
    ..is caused by topological changes in the bone's architectural make-up, chief among which is fenestration of tra becular plates resulting in their conversion to rods and the latter's eventual disruption...
  11. Structural MRI of trabecular bone for therapy response monitoring
    Felix Wehrli; Fiscal Year: 2007
    ..is caused by topological changes in the bone's architectural make-up, chief among which is fenestration of tra becular plates resulting in their conversion to rods and the latter's eventual disruption...
  12. Biology-Pathology of Arbovirus Persistence in a Mosquito Host
    Doria Bowers; Fiscal Year: 2007
    ..virus variants, selected for during chronic infection will be isolated; persistent (SIN-PI#), tracheole (SIN-TRA#) & saliva (SIN-SPIT#)...
  13. Control by tra-1 of sexual differentiation in C. elegans
    David Zarkower; Fiscal Year: 2004
    ..In the nematode Caenorhabditis elegans, the activity of a single gene, tra-1, is necessary and sufficient to dictate whether the entire body develops as male or female...
  14. Structural Basis for Synergistic Gene Expression by Runx1 and Ets1 Proteins
    Tahir Tahirov; Fiscal Year: 2009
    ..basis of cooperative DNA binding by Runx1 and Ets1 will be determined using composite Ets-Runx binding elements of TCRa and Mo-MLV enhancers, which represent examples of higher (>30 fold) and lower (~10) degrees of cooperative ..
  15. Structural Basis for Synergistic Gene Expression by Runx1 and Ets1 Proteins
    Tahir H Tahirov; Fiscal Year: 2010
    ..basis of cooperative DNA binding by Runx1 and Ets1 will be determined using composite Ets-Runx binding elements of TCRa and Mo-MLV enhancers, which represent examples of higher (>30 fold) and lower (~10) degrees of cooperative ..
  16. SELECTION OF T CELL RECEPTOR V-ALPHA REGIONS
    NICHOLAS GASCOIGNE; Fiscal Year: 2001
    ..by an investigator who is interested in control of expression of the alpha gene of the T-cell antigen receptor (TCRa)...
  17. Regulation of Cutaneous Inflammation by local gd T Cells
    Robert Tigelaar; Fiscal Year: 2007
    ..Combined use of different strains of TCRd-/- (knockout) mice and selective reconstitution of such mice via adoptive transfer has shown that Vgamma5+ DETC, ..
  18. Rhodopsin-mediated activation of alternative transduction pathways.
    Janis Lem; Fiscal Year: 2007
    ..We will isolate alternative pathway(s) using transgenic mice with null mutations in the transducin a-subunit (Tra-/-) and/or arrestin (Arr-/-) genes...