Gene Symbol: TNFRSF10C
Description: TNF receptor superfamily member 10c
Alias: CD263, DCR1, DCR1-TNFR, LIT, TRAIL-R3, TRAILR3, TRID, tumor necrosis factor receptor superfamily member 10C, TNF-related apoptosis-inducing ligand receptor 3, antagonist decoy receptor for TRAIL/Apo-2L, cytotoxic TRAIL receptor-3, decoy TRAIL receptor without death domain, decoy receptor 1, lymphocyte inhibitor of TRAIL, tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
Species: human
Products:     TNFRSF10C

Top Publications

  1. Tarragona J, Llecha N, Santacana M, Lopez S, Gatius S, Llobet D, et al. DcR1 expression in endometrial carcinomas. Virchows Arch. 2010;456:39-44 pubmed publisher
    ..Up-regulation of decoy receptors, DcR1 and DcR2, may result in diminished binding of TRAIL to their functional receptors...
  2. Pan G, Ni J, Wei Y, Yu G, Gentz R, Dixit V. An antagonist decoy receptor and a death domain-containing receptor for TRAIL. Science. 1997;277:815-8 pubmed
    ..An antagonist decoy receptor (designated as TRID for TRAIL receptor without an intracellular domain) that may explain the resistant phenotype of normal tissues was ..
  3. Sheridan J, Marsters S, Pitti R, Gurney A, Skubatch M, Baldwin D, et al. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science. 1997;277:818-21 pubmed
    ..The receptor designated decoy receptor 1 (DcR1) displayed properties of a glycophospholipid-anchored cell surface protein...
  4. Merino D, Lalaoui N, Morizot A, Schneider P, Solary E, Micheau O. Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2. Mol Cell Biol. 2006;26:7046-55 pubmed
    ..TRAIL can also bind decoy receptor 1 (DcR1) (TRAIL-R3) and DcR2 (TRAIL-R4) that fail to induce apoptosis since they lack and have a truncated ..
  5. Toscano F, Fajoui Z, Gay F, Lalaoui N, Parmentier B, Chayvialle J, et al. P53-mediated upregulation of DcR1 impairs oxaliplatin/TRAIL-induced synergistic anti-tumour potential in colon cancer cells. Oncogene. 2008;27:4161-71 pubmed publisher
    ..Impaired TRAIL-induced cell death resulted from a strong p53 dependent, oxaliplatin-mediated, DcR1 receptor expression increase...
  6. Cheng Y, Kim J, Liu W, Dunn T, Luo J, Loza M, et al. Genetic and epigenetic inactivation of TNFRSF10C in human prostate cancer. Prostate. 2009;69:327-35 pubmed publisher
    b>TNFRSF10C, is located on 8p21.3, one of the most frequently deleted loci in the genome of prostate cancer (PCa). Hypermethylation of TNFRSF10C promoter CpG island (CGI) had been reported in many tumors including PCa...
  7. Rondón Mercado R, Acosta H, Cáceres A, Quiñones W, Concepcion J. Subcellular localization of glycolytic enzymes and characterization of intermediary metabolism of Trypanosoma rangeli. Mol Biochem Parasitol. 2017;216:21-29 pubmed publisher
    ..Furthermore, we demonstrate that T. rangeli epimastigotes growing in LIT medium only consume glucose and do not excrete ammonium; moreover, they are unable to survive in partially-depleted ..
  8. Kindu M, Aklilu E, Balkew M, Gebre Michael T. Study on the species composition and ecology of anophelines in Addis Zemen, South Gondar, Ethiopia. Parasit Vectors. 2018;11:215 pubmed publisher
    ..Only the former three species were captured in the adult collections. Sun-lit Sheni stream, rain pools, hoof prints, drainage and irrigation canals were found to be habitats of larvae...
  9. Wille Bille A, Miranda Morales R, Pucci M, Bellia F, D Addario C, Pautassi R. Prenatal ethanol induces an anxiety phenotype and alters expression of dynorphin & nociceptin/orphanin FQ genes. Prog Neuropsychopharmacol Biol Psychiatry. 2018;85:77-88 pubmed publisher
    ..PEE rats exhibited hypolocomotion in the OF, greater avoidance of the white and brightly lit areas in the LDB and CSF, and greater preference for the sheltered area in the CSF test...

More Information

Publications128 found, 100 shown here

  1. Ford C, Kim M, Dancy B. Perceptions of hypertension and contributing personal and environmental factors among rural Southern African American women. Ethn Dis. 2009;19:407-13 pubmed centers, or malls to walk around were not available in all communities, and not all sidewalks were well-lit, limiting their walking exercise opportunities after work hours...
  2. Xie Q, McGreal R, Harris R, Gao C, Liu W, Reneker L, et al. Regulation of c-Maf and αA-Crystallin in Ocular Lens by Fibroblast Growth Factor Signaling. J Biol Chem. 2016;291:3947-58 pubmed publisher
    ..c-Maf regulates expression of αA-crystallin (Cryaa) through binding to its promoter and distal enhancer, DCR1, both activated by FGF2 in cell culture...
  3. Sundaram K, Sambandam Y, Balasubramanian S, Pillai B, Voelkel Johnson C, Ries W, et al. STAT-6 mediates TRAIL induced RANK ligand expression in stromal/preosteoblast cells. Bone. 2015;71:137-44 pubmed publisher
    ..Herein, we show that TRAIL increases DR5 and DcR1 receptors but no change in the levels of DR4 and DcR2 expression in human bone marrow derived stromal/preosteoblast ..
  4. Lobo Rojas Á, González Marcano E, Valera Vera E, Acosta H, Quiñones W, Burchmore R, et al. Trypanosoma cruzi contains two galactokinases; molecular and biochemical characterization. Parasitol Int. 2016;65:472-82 pubmed publisher
    ..Epimastigotes of T. cruzi can grow in glucose-depleted LIT-medium supplemented with 20mM of galactose, suggesting that this hexose, upon phosphorylation by a TcGALK, could be ..
  5. Kim Y, Shin E, Jung J, Park J, Koo J, Koo J, et al. Galbanic acid potentiates TRAIL induced apoptosis in resistant non-small cell lung cancer cells via inhibition of MDR1 and activation of caspases and DR5. Eur J Pharmacol. 2019;847:91-96 pubmed publisher
    ..Furthermore, combination of GBA and TRAIL remarkably inhibited the expression of decoy receptor 1 (DcR1) and multidrug resistance 1(MDR1) in H460/R cells...
  6. Lui J, Colbert M, Cheung C, Ad M, Lee A, Zhu Z, et al. Cartilage-Targeted IGF-1 Treatment to Promote Longitudinal Bone Growth. Mol Ther. 2019;27:673-680 pubmed publisher
    ..Using a GH-deficient (lit) mouse model, we found that subcutaneous injections of these CaAb-IGF-1 fusion proteins increased overall growth ..
  7. Dhamija I, Parle M, Kumar S. Antidepressant and anxiolytic effects of Garcinia indica fruit rind via monoaminergic pathway. 3 Biotech. 2017;7:131 pubmed publisher maze, enhanced incidence of head dipping in holes of hole board along with duration of expending time in lit compartment of light dark model, exhibiting its anti-anxiety effect...
  8. Mitova M, Campelos P, Goujon Ginglinger C, Maeder S, Mottier N, Rouget E, et al. Comparison of the impact of the Tobacco Heating System 2.2 and a cigarette on indoor air quality. Regul Toxicol Pharmacol. 2016;80:91-101 pubmed publisher
    ..recommended for simulating "Office", "Residential" and "Hospitality" environments and was compared with smoking a lit-end cigarette (Marlboro Gold) under identical experimental conditions...
  9. Fardo D, Katsumata Y, Kauwe J, Deming Y, Harari O, Cruchaga C, et al. CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN/PGRN. Exp Gerontol. 2017;90:83-89 pubmed publisher
    ..015). These data are remarkable since this GRN SNP has been found to be a risk factor for multiple types of dementia-related brain pathologies. ..
  10. Pereira M, de Morais H, Dos Santos Silva E, Corso C, Adami E, Carlos R, et al. The antioxidant gallic acid induces anxiolytic-, but not antidepressant-like effect, in streptozotocin-induced diabetes. Metab Brain Dis. 2018;33:1573-1584 pubmed publisher
    ..the end arm exploration and head dips when evaluated in the EPM test; moreover, a decrease in the spent time in the lit compartment of LDT test was observed, suggesting an anxiogenic-like behavior...
  11. Armbruster K, Meredith T. Identification of the Lyso-Form N-Acyl Intramolecular Transferase in Low-GC Firmicutes. J Bacteriol. 2017;199: pubmed publisher
    ..As such, the discovered gene has been named lipoprotein intramolecular transacylase (lit), to differentiate it from the gene for the intermolecular N-acyltransferase (lnt) involved in ..
  12. Frohman L. New insights into the regulation of somatotrope function using genetic and transgenic models. Metabolism. 1996;45:1-3 pubmed
    ..Genetic models of impaired GH secretion include the little (lit) mouse, the dwarf (dw) rat, the fatty (fa) rat, and the high-growth (hg) mouse...
  13. Ranneva S, Pavlov K, Gromova A, Amstislavskaya T, Lipina T. Features of emotional and social behavioral phenotypes of calsyntenin2 knockout mice. Behav Brain Res. 2017;332:343-354 pubmed publisher
    ..Clstn2-KO mice demonstrated high exploration and hyperactivity in the dimly lit EPM that affect anxiety parameters...
  14. Passari A, Mishra V, Singh G, Singh P, Kumar B, Gupta V, et al. Insights into the functionality of endophytic actinobacteria with a focus on their biosynthetic potential and secondary metabolites production. Sci Rep. 2017;7:11809 pubmed publisher
    ..acid, ferulic acid, arjunic acid, gallic acid and boswellic acid) were detected and quantified using UHPLC-QqQLIT-MS/MS...
  15. Al Bayan M, Islam N, Edwards S, Duncan D. Neighborhood perceptions and hypertension among low-income black women: a qualitative study. BMC Public Health. 2016;16:1075 pubmed
    ..g. healthy food stores to encourage good nutrition habits and well-lit walking paths to encourage daily exercise), in addition to interventions that increase hypertension awareness in ..
  16. Cantillo J, Puerta L, Lafosse Marin S, Subiza J, Caraballo L, Fernández Caldas E. Allergens involved in the cross-reactivity of Aedes aegypti with other arthropods. Ann Allergy Asthma Immunol. 2017;118:710-718 pubmed publisher
    ..0201, Der p 10, Blo t 10, Lit v 1, and Per a 7)...
  17. Haverroth G, Welang C, Mocelin R, Postay D, Bertoncello K, Franscescon F, et al. Copper acutely impairs behavioral function and muscle acetylcholinesterase activity in zebrafish (Danio rerio). Ecotoxicol Environ Saf. 2015;122:440-7 pubmed publisher
    ..changes in behavioral profile of zebrafish by changing locomotion and natural tendency to avoid brightly lit area. On the other hand, there were no significant effects on parameters related to oxidative stress...
  18. Palazzotto E, Renzone G, Fontana P, Botta L, Scaloni A, Puglia A, et al. Tryptophan promotes morphological and physiological differentiation in Streptomyces coelicolor. Appl Microbiol Biotechnol. 2015;99:10177-89 pubmed publisher
    ..Combined 2D-DIGE and nano liquid chromatography electrospray linear ion trap tandem mass spectrometry (LC-ESI-LIT-MS/MS) analyses revealed that tryptophan exerts a growth-stage-dependent global effect on S...
  19. Argiriadis E, Battistel D, McWethy D, Vecchiato M, Kirchgeorg T, Kehrwald N, et al. Lake sediment fecal and biomass burning biomarkers provide direct evidence for prehistoric human-lit fires in New Zealand. Sci Rep. 2018;8:12113 pubmed publisher
    ..Testing our approach in a context of well-established fire history provides a new tool for understanding cause-effect relationships in more complex continental reconstructions. ..
  20. Stadlmair L, Grosse S, Letzel T, Drewes J, Grassmann J. Comprehensive MS-based screening and identification of pharmaceutical transformation products formed during enzymatic conversion. Anal Bioanal Chem. 2019;411:339-351 pubmed publisher
    ..multiple reaction monitoring (MRM) modes using a hybrid triple quadrupole-linear ion trap-mass spectrometer (QqQ/LIT-MS). "Suspect" MRM modes did not provide a significant sensitivity improvement compared to EPI experiments...
  21. Ellahi A, Rine J. Evolution and Functional Trajectory of Sir1 in Gene Silencing. Mol Cell Biol. 2016;36:1164-79 pubmed publisher
    ..In contrast to the prominent role of Sir proteins in silencing, T. delbrueckii RNAi genes AGO1 and DCR1 did not function in heterochromatin formation...
  22. Margioto Teston A, Paula de Abreu A, Gruendling A, Bahia M, Gomes M, Marques de Araújo S, et al. Differential parasitological, molecular, and serological detection of Trypanosoma cruzi I, II, and IV in blood of experimentally infected mice. Exp Parasitol. 2016;166:44-50 pubmed publisher
    ..from experimentally infected mice and analyzed by fresh blood examination, hemoculture in Liver Infusion Tryptose (LIT) medium, polymerase chain reaction (PCR), and enzyme-linked immunosorbent assay (ELISA)...
  23. Dos Santos M, de Macedo G, Prestes A, Loro V, Heidrich G, Picoloto R, et al. Hyperglycemia elicits anxiety-like behaviors in zebrafish: Protective role of dietary diphenyl diselenide. Prog Neuropsychopharmacol Biol Psychiatry. 2018;85:128-135 pubmed publisher
    ..In the novel tank diving test, glucose decreased vertical exploration and fish spent less time in the lit area when tested in the light-dark test, suggesting increased anxiety-like behavior...
  24. Cheng X, Buckley D, Klaassen C. Regulation of hepatic bile acid transporters Ntcp and Bsep expression. Biochem Pharmacol. 2007;74:1665-76 pubmed
    ..Hormone replacements conducted in gonadectomized, hypophysectomized, and lit/lit mice indicate that female-predominant Ntcp expression in mouse liver is due to the inhibitory effect of male-..
  25. Korshunova T, Vorontsov D, Dyakonova V. Previous motor activity affects the transition from uncertainty to decision making in snails. J Exp Biol. 2016;219:3635-3641 pubmed
    ..The first phase was prolonged when the test arena was symmetrically lit, compared with one with an apparent gradient of light...
  26. Gowda N, Vallesha N, Awachat V, Anandan S, Pal D, Prasad C. Study on evaluation of silage from pineapple (Ananas comosus) fruit residue as livestock feed. Trop Anim Health Prod. 2015;47:557-61 pubmed publisher
    ..0 lit per cow and fat content by 0...
  27. Depino A. Early prenatal exposure to LPS results in anxiety- and depression-related behaviors in adulthood. Neuroscience. 2015;299:56-65 pubmed publisher
    ..prenatally exposed to LPS avoided the open arms of an elevated plus maze, the center of an open field and the lit side of a light/dark box, and they spent more time immobile in both the forced swimming and tail suspension tests, ..
  28. Ileri A, Koseoglu R, Markoc F, Etikan I, Atilgan D, Deresoy F. Immunohistochemical Analysis of the Extrinsic Apoptosis Process in the Non-Neoplastic and Neoplastic Prostate. Turk Patoloji Derg. 2018;34:19-28 pubmed publisher
    ..While Fas and FasL were evaluated in glandular and stromal areas, DcR1 and FLIP were evaluated in only glandular areas...
  29. Yang Z, Ma J. Actein enhances TRAIL effects on suppressing gastric cancer progression by activating p53/Caspase-3 signaling. Biochem Biophys Res Commun. 2018;497:1177-1183 pubmed publisher
    ..ACT were sensitive to TRAIL-triggered apoptotic response by enhancing Caspases cleavage, due to elevation of decoy receptor 1 and 2 (DcR1 and DcR2) dependent on p53...
  30. Schneider P, Bodmer J, Thome M, Hofmann K, Holler N, Tschopp J. Characterization of two receptors for TRAIL. FEBS Lett. 1997;416:329-34 pubmed
    ..All three TRAIL receptors bind TRAIL with similar affinity, suggesting a complex regulation of TRAIL-mediated signals. ..
  31. Wu N, Bao L, Ding L, Ju H. A Single Excitation-Duplexed Imaging Strategy for Profiling Cell Surface Protein-Specific Glycoforms. Angew Chem Int Ed Engl. 2016;55:5220-4 pubmed publisher
    ..Upon excitation at 980?nm, only the dyes linked to protein-specific glycans can be lit up by the donor by two parallel energy transfer processes, for in?situ duplexed imaging of glycoforms on specific ..
  32. Xu Y, Li J, Li Q, Feng Y, Pan F. Betulinic acid promotes TRAIL function on liver cancer progression inhibition through p53/Caspase-3 signaling activation. Biomed Pharmacother. 2017;88:349-358 pubmed publisher
    ..BA were sensitive to APO2-triggered apoptotic response by enhancing Caspases cleavage, due to elevation of decoy receptor 1 and 2 (DcR1 and DcR2) dependent on p53...
  33. Lane J, Shafto P. Young children's attributions of causal power to novel invisible entities. J Exp Child Psychol. 2017;162:268-281 pubmed publisher
    ..During this introduction, children watched as one container was inverted over a box and the box lit up green, and then another identical container was inverted over the box and the box did not light up...
  34. Niemierzycka A, Tomczuk K, Mikicin M, Zdrodowska A, Orzechowski G, Kowalczyk M. Examinations of the methods used to power supply of different light sources and their effect on bioelectrical brain activity. Neurol Neurochir Pol. 2018;52:505-513 pubmed publisher
    ..Twenty healthy men aged 19-25 years participated in the experiment. The research stand was lit by: LED diodes with color temperatures of 3000K, 4200K, 6500K, with the power supplied using the pulse width ..
  35. Dorr J, Bechmann I, Waiczies S, Aktas O, Walczak H, Krammer P, et al. Lack of tumor necrosis factor-related apoptosis-inducing ligand but presence of its receptors in the human brain. J Neurosci. 2002;22:RC209 pubmed
    ..Conversely, this death receptor-ligand system might well play an important role in T cell-mediated autoimmune diseases of the CNS such as multiple sclerosis. ..
  36. Szulejko J, Kim K. A practical approach to estimate emission rates of indoor air pollutants due to the use of personal combustible products based on small-chamber studies. Chemosphere. 2016;144:1451-8 pubmed publisher
    ..If two scented candles with a formaldehyde emission rate of 310 µg h(-1) each were lit for 4 h in a small 20 m(3) room with an air change rate of 0...
  37. Fairman C, Hyde P, Focht B. Resistance training interventions across the cancer control continuum: a systematic review of the implementation of resistance training principles. Br J Sports Med. 2017;51:677-685 pubmed publisher
    ..Electronic databases (PubMed, EMBASE, CINAHL, Cochrane, PEDro, PsychInfo, Cancer Lit, Sport Discus, AMED, Cochrane Central Register of Controlled Trials) and reference lists of included articles from ..
  38. Mocelin R, Herrmann A, Marcon M, Rambo C, Rohden A, Bevilaqua F, et al. N-acetylcysteine prevents stress-induced anxiety behavior in zebrafish. Pharmacol Biochem Behav. 2015;139 Pt B:121-6 pubmed publisher
    ..anxiety-like behaviors induced by an acute stressor (net chasing), and increased the time zebrafish spent in the lit side in the light/dark test...
  39. Sharma P, Sridhar J, Mehta S. Flashes and Floaters. Prim Care. 2015;42:425-35 pubmed publisher
    ..gel of the eye that cause shadows and thus visual changes, especially against bright backgrounds and in brightly lit environments. Flashes and floaters can occur individually or together...
  40. Elvira Matelot E, Hachet M, Shamandi N, Comella P, Sáez Vásquez J, Zytnicki M, et al. Arabidopsis RNASE THREE LIKE2 Modulates the Expression of Protein-Coding Genes via 24-Nucleotide Small Interfering RNA-Directed DNA Methylation. Plant Cell. 2016;28:406-25 pubmed publisher a unique Arabidopsis RNaseIII enzyme resembling the budding yeast small interfering RNA (siRNA)-producing Dcr1 enzyme...
  41. Wang B, Wang L, Chen F, Yang X, Ding M, Zhang Z, et al. MicroRNA profiling of the whitefly Bemisia tabaci Middle East-Aisa Minor I following the acquisition of Tomato yellow leaf curl China virus. Virol J. 2016;13:20 pubmed publisher
    ..Sequences of Argonaute 1(Ago1) and Dicer 1 (Dcr1) genes were cloned from B. tabaci MEAM1 cDNAs...
  42. Futai K, Terasaka N, Katoh T, Suga H. tRid, an enabling method to isolate previously inaccessible small RNA fractions. Methods. 2016;106:105-11 pubmed publisher
    ..We here report a method, named tRid (tRNA rid), for removing abundant tRNAs from small RNA fractions regardless of tRNA sequence species...
  43. Borbély E, Hajna Z, Nabi L, Scheich B, Tékus V, László K, et al. Hemokinin-1 mediates anxiolytic and anti-depressant-like actions in mice. Brain Behav Immun. 2017;59:219-232 pubmed publisher
    ..spent significantly less, while Tacr1-/- and CP99994-treated mice spent significantly more time in the lit compartment...
  44. Goldstein A, Gans S, Ripley Moffitt C, Kotsen C, Bars M. Use of Expired Air Carbon Monoxide Testing in Clinical Tobacco Treatment Settings. Chest. 2017;: pubmed publisher
    ..objective contribution to the assessment of smoking behavior, as CO is rapidly absorbed into the bloodstream when lit cigarettes or cigars are inhaled...
  45. Kyba C, Kuester T, Sánchez de Miguel A, Baugh K, Jechow A, Hölker F, et al. Artificially lit surface of Earth at night increasing in radiance and extent. Sci Adv. 2017;3:e1701528 pubmed publisher
    ..calibrated satellite radiometer designed for night lights to show that from 2012 to 2016, Earth's artificially lit outdoor area grew by 2.2% per year, with a total radiance growth of 1.8% per year...
  46. Lebhardt F, Desplan C. Retinal perception and ecological significance of color vision in insects. Curr Opin Insect Sci. 2017;24:75-83 pubmed publisher
    ..relies on the ability to discriminate different wavelengths and is often improved in insects that inhabit well-lit, spectrally rich environments...
  47. Fajemila O, Langer M, Lipps J. Spatial Patterns in the Distribution, Diversity and Abundance of Benthic Foraminifera around Moorea (Society Archipelago, French Polynesia). PLoS ONE. 2015;10:e0145752 pubmed publisher
    ..foraminifera (Borelis, Amphistegina, Heterostegina, Peneroplis) generally live in the oligotrophic, well-lit back- and fore-reef environments...
  48. Götz U, Marker S, Cheaib M, Andresen K, Shrestha S, Durai D, et al. Two sets of RNAi components are required for heterochromatin formation in trans triggered by truncated transgenes. Nucleic Acids Res. 2016;44:5908-23 pubmed publisher well as a second set of components, which are also involved in post-transcriptional silencing: RDR2, PTIWI13, DCR1 and CID2...
  49. Młyniec K, Starowicz G, Gaweł M, Frąckiewicz E, Nowak G. Potential antidepressant-like properties of the TC G-1008, a GPR39 (zinc receptor) agonist. J Affect Disord. 2016;201:179-84 pubmed publisher
    ..we observed the opposite results in the light/dark box (decreased overall distance; increased time spent in the lit compartment; decreased time spent in the dark compartment; increased freezing time) and elevated plus maze (no ..
  50. Park J, Seo Y, Lee J. Antimicrobial Susceptibilities of Enterobacteriaceae in Community-Acquired Urinary Tract Infections during a 5-year Period: A Single Hospital Study in Korea. Infect Chemother. 2017;49:184-193 pubmed publisher
    ..empirical antibiotics numerically by calculating the syndrome-specific likelihood of inadequate therapy (LIT) for the last 2 years (interpretation of the LIT A value: 1 out of A people is likely to receive inadequate ..
  51. Singh G, Passsari A, Singh P, Leo V, Subbarayan S, Kumar B, et al. Pharmacological potential of Bidens pilosa L. and determination of bioactive compounds using UHPLC-QqQLIT-MS/MS and GC/MS. BMC Complement Altern Med. 2017;17:492 pubmed publisher
    ..Additionally, the major phenolic and volatile compounds were determined using UHPLC-QqQLIT-MS/MS and GC/MS respectively. We found that the extract showed highest antimicrobial activity against E...
  52. Shen Y, Cheng R, Xiao W, Yang S, Guo Y, Wang N, et al. Labile organic carbon pools and enzyme activities of Pinus massoniana plantation soil as affected by understory vegetation removal and thinning. Sci Rep. 2018;8:573 pubmed publisher
    ..regular shrub cutting with the simultaneous removal of residues (SC), a site under low-intensity thinning (LIT), and a site under high-intensity thinning (HIT) were compared for soil labile organic carbon (LOC), related enzyme ..
  53. Castro Mejía J, Muhammed M, Kot W, Neve H, Franz C, Hansen L, et al. Optimizing protocols for extraction of bacteriophages prior to metagenomic analyses of phage communities in the human gut. Microbiome. 2015;3:64 pubmed publisher
    ..PEG) approaches using an adapted method from a published protocol as control (literature-adapted protocol (LIT))...
  54. Bordin K, Saladino F, Fernández Blanco C, Ruiz M, Manes J, Fernandez Franzón M, et al. Reaction of zearalenone and ?-zearalenol with allyl isothiocyanate, characterization of reaction products, their bioaccessibility and bioavailability in vitro. Food Chem. 2017;217:648-654 pubmed publisher
    ..and also determines the bioaccessibility and bioavailability of the reaction products isolated and identified by MS-LIT. Mycotoxin reductions were dose-dependent, and ZEA levels decreased more than ?-ZOL, ranging from 0.2 to 96...
  55. Ooms M, Graham P, Nguyen B, Sargent E, Sinton D. Light dilution via wavelength management for efficient high-density photobioreactors. Biotechnol Bioeng. 2017;114:1160-1169 pubmed publisher
    ..Taken together, these results indicate that, particularly for artificially lit photobioreactors, wavelength needs to be included as a critical operational parameter to maintain optimal ..
  56. Rabin J, Houser B, Talbert C, Patel R. Measurement of dark adaptometry during ISCEV standard flash electroretinography. Doc Ophthalmol. 2017;135:195-208 pubmed publisher
    ..It provides an additional benchmark for monitoring function over time and invaluable guidance for patients functioning in dimly lit settings.
  57. Zhang X, Nguyen T, Thomas W, Sanders J, Hersey P. Mechanisms of resistance of normal cells to TRAIL induced apoptosis vary between different cell types. FEBS Lett. 2000;482:193-9 pubmed
    ..Differential subcellular location of decoy receptors may be an important determinant of their effectiveness in different types of normal cells. ..
  58. Sejdić E, Millecamps A, Teoli J, Rothfuss M, Franconi N, Perera S, et al. Assessing interactions among multiple physiological systems during walking outside a laboratory: An Android based gait monitor. Comput Methods Programs Biomed. 2015;122:450-61 pubmed publisher
    Gait function is traditionally assessed using well-lit, unobstructed walkways with minimal distractions...
  59. Meyer E, Seale L, Permar B, McClary A. The Effect of Chemical Treatments on Lampenflora and a Collembola Indicator Species at a Popular Tour Cave in California, USA. Environ Manage. 2017;59:1034-1042 pubmed publisher
    ..chemicals at various concentrations have been utilized to remove phototrophic lampenflora colonizing artificially lit surfaces within these caves; however formulations, effectiveness, and impacts appear anecdotal and temporally ..
  60. Brandt N, Dethlefsen M, Bangsbo J, Pilegaard H. PGC-1? and exercise intensity dependent adaptations in mouse skeletal muscle. PLoS ONE. 2017;12:e0185993 pubmed publisher
    ..In addition PGC-1? KO and littermate WT mice were exercise trained at either low intensity (LIT) for 40 min or at moderate intensity (MIT) for 20 min 2 times pr. day for 5 weeks...
  61. Durdle A, Verdon T, Mitchell R, van Oorschot R. Location of Artifacts Deposited by the Blow Fly Lucilia cuprina After Feeding on Human Blood at Simulated Indoor Crime Scenes. J Forensic Sci. 2017;: pubmed publisher
    ..The location of flies and artifacts was recorded after 72 h. It was found flies may move toward warm or well-lit areas and deposit artifacts there, but artifacts were predominantly located around food sources and were often ..
  62. Scappaticci G, Marini B, Nachar V, Uebel J, Vulaj V, Crouch A, et al. Outcomes of previously untreated elderly patients with AML: a propensity score-matched comparison of clofarabine vs. FLAG. Ann Hematol. 2018;97:573-584 pubmed publisher
    ..Clofarabine-based induction (CLO) provides an alternative to low-intensity therapy (LIT) and palliative care for this population, but supporting data are conflicted...
  63. Hoskin C. A new frog species (Microhylidae:Cophixalus) from boulder-pile habitat of Cape Melville, north-east Australia. Zootaxa. 2013;3722:61-72 pubmed
    ..I speculate that the latter trait is an adaptation to dimly lit conditions deep within the boulder-field. Cophixalus petrophilus sp. nov...
  64. Patil A, Chou S, Chang P, Lee C, Cheng C, Chu M, et al. High Mass Ion Detection with Charge Detector Coupled to Rectilinear Ion Trap Mass Spectrometer. J Am Soc Mass Spectrom. 2017;28:1066-1078 pubmed publisher
    Conventional linear ion trap mass analyzers (LIT-MS) provide high ion capacity and show their MS n ability; however, the detection of high mass ions is still challenging because LIT-MS with secondary electron detectors (SED) ..
  65. Khangembam R, Singh H, Jyoti -, Rath S, Singh N. Effect of synergists on ivermectin resistance in field populations of Rhipicephalus (Boophilus) microplus from Punjab districts, India. Ticks Tick Borne Dis. 2018;9:682-686 pubmed publisher
    ..microplus collected from various districts of the Punjab state, India was determined using larval immersion test (LIT)...
  66. Narayan G, Xie D, Ishdorj G, Scotto L, Mansukhani M, Pothuri B, et al. Epigenetic inactivation of TRAIL decoy receptors at 8p12-21.3 commonly deleted region confers sensitivity to Apo2L/trail-Cisplatin combination therapy in cervical cancer. Genes Chromosomes Cancer. 2016;55:177-89 pubmed publisher
    ..analyses of candidate genes at MDR identified promoter hypermethylation and/or inactivation of decoy receptors TNFRSF10C and TNFRSF10D in the majority of CC patients...
  67. Giannoukos S, Agapiou A, Taylor S. Advances in chemical sensing technologies for VOCs in breath for security/threat assessment, illicit drug detection, and human trafficking activity. J Breath Res. 2018;12:027106 pubmed publisher
    ..g. non-scanning digital light processing linear ion trap MS (DLP-LIT-MS), nanoparticles, mid-infrared photo-acoustic spectroscopy and hyphenated technologies)...
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    ..These results indicate that tryptophol induces apoptosis through DR5 and that the resistance of PBL to tryptophol-induced apoptosis might be due to competition from DcR1.
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    ..was observed for two protein phosphatase subunit genes (PPP2CB, PPP3CC) and two TRAIL decoy receptors (TNFRSF10C/DcR1, TNFRSF10D/DcR2), but not for the three established candidates nor for TRAIL death receptor genes...
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    ..Five pancreatic cell lines were investigated for the expression of FasL/Fas, DcR3, DR4, DR5/TRAIL, DcR1, DcR2, and other death pathways related molecules such as Bax, bcl-xL, bcl-2, FADD, and caspase-3 by flow cytometry,..
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    ..These findings give new insight into the resistance mechanisms of pancreatic cancer towards TRAIL-mediated apoptosis. ..
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  74. Leverkus M, Walczak H, McLellan A, Fries H, Terbeck G, Brocker E, et al. Maturation of dendritic cells leads to up-regulation of cellular FLICE-inhibitory protein and concomitant down-regulation of death ligand-mediated apoptosis. Blood. 2000;96:2628-31 pubmed
    ..Induction of apoptosis by TRAIL or CD95L does not seem to play a role in the elimination of mature DCs, but instead might serve to regulate immature DC populations. ..
  75. Carlson S, Paul P, Watson K, Schmid T, Fulton J. How reported usefulness modifies the association between neighborhood supports and walking behavior. Prev Med. 2016;91:76-81 pubmed publisher
    ..supports (shops within walking distance, transit stops, sidewalks, parks, interesting things to look at, well-lit at night, low crime rate, and cars following speed limit) were examined in 3973 adults who completed the 2014 ..
  76. Bosch L, Trooskens G, Snaebjornsson P, Coupé V, Mongera S, Haan J, et al. Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer. Oncotarget. 2017;8:63140-63154 pubmed publisher
    ..In the discovery (n=185) and initial validation set (n=166), patients with methylated Decoy Receptor 1 (DCR1) did not benefit from CAPIRI over Capecitabine treatment (discovery set: HR=1.2 (95%CI 0.7-1...
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    ..This grand natural scene was a physical correlate of Francis's intellectual world: wide-ranging, brilliantly lit, a little overawing, but also immensely inviting and above all an exciting place to be." (Mitchison, 2004).
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    ..elegans amphid sensory organ to restrict sensory compartment size. LIT-1, a Nemo-like kinase, and SNX-1, a retromer component, antagonize DAF-6 and promote compartment expansion...
  79. Cruz Saavedra L, Munoz M, León C, Patarroyo M, Arévalo G, Pavia P, et al. Purification of Trypanosoma cruzi metacyclic trypomastigotes by ion exchange chromatography in sepharose-DEAE, a novel methodology for host-pathogen interaction studies. J Microbiol Methods. 2017;142:27-32 pubmed publisher
    ..Therefore, herein we tested its ability to purify metacyclic trypomastigotes in Liver Infusion Triptose (LIT) medium cultures...
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    It is commonly assumed that saccades in the dark are slower than saccades in a lit room...
  81. Shivapurkar N, Toyooka S, Toyooka K, Reddy J, Miyajima K, Suzuki M, et al. Aberrant methylation of trail decoy receptor genes is frequent in multiple tumor types. Int J Cancer. 2004;109:786-92 pubmed
    ..different receptors, 2 proapoptotic (DR4 and DR5), and 2 potentially antiapoptotic receptors lacking death domains (DcR1 and DcR2)...
  82. Cho S, Kim J, Ryu H, Kim J, Kim H, Park J, et al. Identification of single nucleotide polymorphisms in the tumor necrosis factor (TNF) and TNF receptor superfamily in the Korean population. Hum Immunol. 2004;65:710-8 pubmed
    ..90, p < 0.001). The validated SNPs in the TNF-TNFR superfamily would be valuable for association studies with several immune-mediated human diseases. ..
  83. Mattos E, Meira Strejevitch C, Marciano M, Faccini C, Lourenço A, Pereira Chioccola V. Molecular detection of Trypanosoma cruzi in acai pulp and sugarcane juice. Acta Trop. 2017;176:311-315 pubmed publisher
    ..qPCR using a specific molecular marker for T. cruzi. The seeding in LIT medium of experimentally contaminated foods was effective in detecting the parasitic load by qPCR...
  84. Mongkolsapaya J, Cowper A, Xu X, Morris G, McMichael A, Bell J, et al. Lymphocyte inhibitor of TRAIL (TNF-related apoptosis-inducing ligand): a new receptor protecting lymphocytes from the death ligand TRAIL. J Immunol. 1998;160:3-6 pubmed
    ..We have cloned LIT (lymphocyte inhibitor of TRAIL), which lacks a death domain...
  85. Daigle I, Simon H. Alternative functions for TRAIL receptors in eosinophils and neutrophils. Swiss Med Wkly. 2001;131:231-7 pubmed
    ..Alternatively, TRAIL may limit cytokine-mediated antiapoptosis under certain inflammatory conditions. ..
  86. Ruiz de Almodovar C, Ruiz Ruiz C, Rodriguez A, Ortiz Ferrón G, Redondo J, Lopez Rivas A. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) decoy receptor TRAIL-R3 is up-regulated by p53 in breast tumor cells through a mechanism involving an intronic p53-binding site. J Biol Chem. 2004;279:4093-101 pubmed
    ..This is particularly important in view of the proposed use of TRAIL in antitumor therapy. ..
  87. Lum J, Schnepple D, Badley A. Acquired T-cell sensitivity to TRAIL mediated killing during HIV infection is regulated by CXCR4-gp120 interactions. AIDS. 2005;19:1125-33 pubmed
    ..These results indicate that chemokine receptor interactions regulate TRAIL receptor expression and provide an explanation for the acquired T cell sensitivity to TRAIL mediated killing death during HIV infection. ..
  88. Venza M, Visalli M, Catalano T, Fortunato C, Oteri R, Teti D, et al. Impact of DNA methyltransferases on the epigenetic regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor expression in malignant melanoma. Biochem Biophys Res Commun. 2013;441:743-50 pubmed publisher
    ..No correlation between methylation status of DR4 and DR5 and gene expression was found. DcR1 and DcR2 were hypermethylated with very high frequency in both cutaneous and uveal melanoma...
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    ..Thus, TRAIL receptor-3 may function as an antagonistic decoy receptor to attenuate the cytotoxic effect of TRAIL in most tissues that are TRAIL+, DR4+, and DR5+. ..
  90. Morissette M, Vachon Beaudoin G, Parent J, Chakir J, Milot J. Increased p53 level, Bax/Bcl-x(L) ratio, and TRAIL receptor expression in human emphysema. Am J Respir Crit Care Med. 2008;178:240-7 pubmed publisher
  91. Labovsky V, Martinez L, Davies K, de Luján Calcagno M, Garcia Rivello H, Wernicke A, et al. Prognostic significance of TRAIL-R3 and CCR-2 expression in tumor epithelial cells of patients with early breast cancer. BMC Cancer. 2017;17:280 pubmed publisher
    ..High levels of TRAIL-R3 and CCR-2 expression in TEpCs identified patients with early breast cancer with poor outcomes. ..
  92. Bretz J, Mezosi E, Giordano T, Gauger P, Thompson N, Baker J. Inflammatory cytokine regulation of TRAIL-mediated apoptosis in thyroid epithelial cells. Cell Death Differ. 2002;9:274-86 pubmed
    ..We also show the in vivo presence of TRAIL and TRAIL receptors DR5 and DcR1 in both normal and inflamed thyroids...