Gene Symbol: TMEM178A
Description: transmembrane protein 178A
Alias: TMEM178, transmembrane protein 178A, transmembrane protein 178
Species: human
Products:     TMEM178A

Top Publications

  1. Yang Z, Yan H, Dai W, Jing J, Yang Y, Mahajan S, et al. Tmem178 negatively regulates store-operated calcium entry in myeloid cells via association with STIM1. J Autoimmun. 2019;: pubmed publisher
    ..Here, we identified Tmem178 as a negative modulator of STIM1 puncta formation in myeloid cells...
  2. Mahajan S, Decker C, Yang Z, Veis D, Mellins E, Faccio R. Plcγ2/Tmem178 dependent pathway in myeloid cells modulates the pathogenesis of cytokine storm syndrome. J Autoimmun. 2019;: pubmed publisher
    ..Intriguingly, the Plcγ2 downstream effector Tmem178, a negative modulator of calcium levels, acts in a negative feedback loop to restrain inflammatory cytokine ..
  3. Decker C, Yang Z, Rimer R, Park Min K, Macaubas C, Mellins E, et al. Tmem178 acts in a novel negative feedback loop targeting NFATc1 to regulate bone mass. Proc Natl Acad Sci U S A. 2015;112:15654-9 pubmed publisher
    ..Here we describe, to our knowledge, the first known function of transmembrane protein 178 (Tmem178), a PLCγ2 downstream target gene, as a critical modulator of the NFATc1 axis...
  4. Kerns S, Ostrer H, Stock R, Li W, Moore J, Pearlman A, et al. Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer. Int J Radiat Oncol Biol Phys. 2010;78:1292-300 pubmed publisher
    ..This study demonstrates the feasibility of a genome-wide approach to investigate genetic predisposition to radiation injury. ..