Gene Symbol: THAP4
Description: THAP domain containing 4
Alias: CGI-36, PP238, THAP domain-containing protein 4
Species: human
Products:     THAP4

Top Publications

  1. Abate F, da Silva Almeida A, Zairis S, Robles Valero J, Couronné L, Khiabanian H, et al. Activating mutations and translocations in the guanine exchange factor VAV1 in peripheral T-cell lymphomas. Proc Natl Acad Sci U S A. 2017;114:764-769 pubmed publisher
    ..generated by a focal deletion-driven alternative splicing mechanism as well as novel VAV1 gene fusions (VAV1-THAP4, VAV1-MYO1F, and VAV1-S100A7) in PTCL...
  2. Roussigne M, Kossida S, Lavigne A, Clouaire T, Ecochard V, Glories A, et al. The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase. Trends Biochem Sci. 2003;28:66-9 pubmed
    ..Our results suggest that the THAP domain is a novel example of a DBD that is shared between cellular proteins and transposases from mobile genomic parasites. ..
  3. Stein J, Hua X, Lee S, Ho A, Leow A, Toga A, et al. Voxelwise genome-wide association study (vGWAS). Neuroimage. 2010;53:1160-74 pubmed publisher
    ..These genes have high relevance to brain structure. This is the first voxelwise genome wide association study to our knowledge, and offers a novel method to discover genetic influences on brain structure. ..
  4. Bianchetti C, Bingman C, Phillips G. Structure of the C-terminal heme-binding domain of THAP domain containing protein 4 from Homo sapiens. Proteins. 2011;79:1337-41 pubmed publisher