TES

Summary

Gene Symbol: TES
Description: testin LIM domain protein
Alias: TESS, TESS-2, testin, testis derived transcript (3 LIM domains)
Species: human
Products:     TES

Top Publications

  1. Tatarelli C, Linnenbach A, Mimori K, Croce C. Characterization of the human TESTIN gene localized in the FRA7G region at 7q31.2. Genomics. 2000;68:1-12 pubmed
    ..allowed us to identify a gene encoding a 421-amino-acid protein with three LIM domains and 89% identity to murine Testin. We determined the genomic structure of the human TESTIN locus and characterized three alternative transcripts...
  2. Tobias E, Hurlstone A, Mackenzie E, McFarlane R, Black D. The TES gene at 7q31.1 is methylated in tumours and encodes a novel growth-suppressing LIM domain protein. Oncogene. 2001;20:2844-53 pubmed
    ..1. We have cloned and characterized a novel gene at this locus. The TES gene lies within the minimal region of overlap of several LOH studies and appears to possess the properties of a ..
  3. Coutts A, MacKenzie E, Griffith E, Black D. TES is a novel focal adhesion protein with a role in cell spreading. J Cell Sci. 2003;116:897-906 pubmed
    Previously, we identified TES as a novel candidate tumour suppressor gene that mapped to human chromosome 7q31.1...
  4. Garvalov B, Higgins T, Sutherland J, Zettl M, Scaplehorn N, Kocher T, et al. The conformational state of Tes regulates its zyxin-dependent recruitment to focal adhesions. J Cell Biol. 2003;161:33-9 pubmed
    The function of the human Tes protein, which has extensive similarity to zyxin in both sequence and domain organization, is currently unknown...
  5. Boëda B, Briggs D, Higgins T, Garvalov B, Fadden A, McDonald N, et al. Tes, a specific Mena interacting partner, breaks the rules for EVH1 binding. Mol Cell. 2007;28:1071-82 pubmed
    ..Here we show that the LIM3 domain of Tes, which lacks the FPPPP motif, binds to the EVH1 domain of Mena, but not to those of VASP or Evl...
  6. Qiu H, Zhu J, Yuan C, Yan S, Yang Q, Kong B. Frequent hypermethylation and loss of heterozygosity of the testis derived transcript gene in ovarian cancer. Cancer Sci. 2010;101:1255-60 pubmed publisher
    Testis derived transcript (TES) is a candidate tumor suppressor gene located at the human chromosome 7q31, and its function in ovarian cancer is still unknown...
  7. Ma H, Weng D, Chen Y, Huang W, Pan K, Wang H, et al. Extensive analysis of D7S486 in primary gastric cancer supports TESTIN as a candidate tumor suppressor gene. Mol Cancer. 2010;9:190 pubmed publisher
    ..Western blot, immunohistochemistry, and RT-PCR were used to assess the protein and mRNA expression of TESTIN (TES) in 50 and 140 primary GC samples, respectively...
  8. Bach I. The LIM domain: regulation by association. Mech Dev. 2000;91:5-17 pubmed
    ..Furthermore, the identification and characterization of factors that interact with LIM domains illuminates mechanisms of combinatorial developmental regulation. ..
  9. Chene L, Giroud C, Desgrandchamps F, Boccon Gibod L, Cussenot O, Berthon P, et al. Extensive analysis of the 7q31 region in human prostate tumors supports TES as the best candidate tumor suppressor gene. Int J Cancer. 2004;111:798-804 pubmed
    ..the D7S486 and D7S2460 microsatellite loci, which contains several candidate tumor suppressor genes (TSG) such as TES, CAV2, CAV1, MET, CAPZA2, ST7 and WNT2...

More Information

Publications125 found, 100 shown here

  1. Griffith E, Coutts A, Black D. RNAi knockdown of the focal adhesion protein TES reveals its role in actin stress fibre organisation. Cell Motil Cytoskeleton. 2005;60:140-52 pubmed
    b>TES was originally identified as a candidate tumour suppressor gene and has subsequently been found to encode a novel focal adhesion protein...
  2. Zhong Y, Zhu J, Wang Y, Zhou J, Ren K, Ding X, et al. LIM domain protein TES changes its conformational states in different cellular compartments. Mol Cell Biochem. 2009;320:85-92 pubmed publisher
    The human TESTIN (TES) is a putative tumor suppressor and localizes to the cytoplasm as a component of focal adhesions and cell contacts. TES contains a PET domain in the NH(2)-terminus and three tandem LIM domains in the COOH-terminus...
  3. Gunduz E, Gunduz M, Beder L, Nagatsuka H, Fukushima K, Sutcu R, et al. Downregulation of TESTIN and its association with cancer history and a tendency toward poor survival in head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg. 2009;135:254-60 pubmed publisher
    To examine the role of TESTIN as a candidate tumor suppressor gene in head and neck carcinogenesis. Mutation and messenger RNA (mRNA) expression analyses. Academic research...
  4. Weeks R, Kees U, Song S, Morison I. Silencing of TESTIN by dense biallelic promoter methylation is the most common molecular event in childhood acute lymphoblastic leukaemia. Mol Cancer. 2010;9:163 pubmed publisher
    ..By screening candidate genes, we have detected frequent and dense methylation of the TESTIN (TES) promoter...
  5. Zhu J, Li X, Kong X, Moran M, Su P, Haffty B, et al. Testin is a tumor suppressor and prognostic marker in breast cancer. Cancer Sci. 2012;103:2092-101 pubmed publisher
    The testin (TES) gene was previously identified in the fragile chromosomal region FRA7G at 7q31.2...
  6. Wu N, Yang G, Tian C, Yi W, He S, Eskedar G, et al. Effects of green tea polyphenols on trace metals level of rats on food restriction and high-fat diet. J Trace Elem Med Biol. 2019;51:91-97 pubmed publisher
    ..Here, we examined the effects of green tea polyphenols (GTPs) on the level of trace elements (TEs) in rats on food restriction or high-fat diet...
  7. Qu C, Cao J, Liu K, Tan B, Zhu C, Li K, et al. Crohn's Disease Complicated With Extensive Thrombosis of Limbs and Mesenteric Arteries: A Case Report and Literature Review. Ann Vasc Surg. 2019;: pubmed publisher
    ..During IBD treatment, we should be aware of the possibility of TEs (especially arterial TEs) and should be alert to the possibility of arterial TEs in young patients with IBD with ..
  8. Afridi H, Talpur F, Kazi T, Brabazon D. Estimation of toxic elements in the samples of different cigarettes and their effect on the essential elemental status in the biological samples of Irish smoker rheumatoid arthritis consumers. Environ Monit Assess. 2015;187:157 pubmed publisher
    ..The concentrations of trace and TEs in biological samples and different components of cigarette were measured by inductively coupled plasma mass ..
  9. Samy R, Thwin M, Stiles B, Satyanarayana Jois S, Chinnathambi A, Zayed M, et al. Novel phospholipase A2 inhibitors from python serum are potent peptide antibiotics. Biochimie. 2015;111:30-44 pubmed publisher
    ..against various Gram-positive and Gram-negative bacteria (Staphylococcus aureus, Burkholderia pseudomallei (KHW and TES strains), and Proteus vulgaris) using a disc-diffusion method (20 μg/disc)...
  10. Finley J. Transposable elements, placental development, and oocyte activation: Cellular stress and AMPK links jumping genes with the creation of human life. Med Hypotheses. 2018;118:44-54 pubmed publisher
    Transposable elements (TEs), also known as "jumping genes", are DNA sequences first described by Nobel laureate Barbara McClintock that comprise nearly half of the human genome and are able to transpose or move from one genomic location ..
  11. Iddawela D, Ehambaram K, Bandara P. Prevalence of Toxocara antibodies among patients clinically suspected to have ocular toxocariasis: A retrospective descriptive study in Sri Lanka. BMC Ophthalmol. 2017;17:50 pubmed publisher
    ..Each serum sample was subjected to Toxocara excretory - secretory antigen ELISA (TES - ELISA). Out of the 250 cases, 155 (62%) were seropositive...
  12. Afridi H, Talpur F, Kazi T, Brabazon D. Effect of Trace and Toxic Elements of Different Brands of Cigarettes on the Essential Elemental Status of Irish Referent and Diabetic Mellitus Consumers. Biol Trace Elem Res. 2015;167:209-24 pubmed publisher
    ..The concentrations of TEs in biological samples and different components of cigarette were measured by inductively coupled plasma atomic ..
  13. Delgado López P, Rodríguez Salazar A, Martín Velasco V, Castilla Díez J, Martín Alonso J, Galacho Harriero A, et al. [Total en bloc spondylectomy for spinal tumours: Technical aspects and surgical details]. Neurocirugia (Astur). 2017;28:51-66 pubmed publisher
    ..lessons learned with a series of patients suffering from spinal tumours that underwent total en bloc spondylectomy (TES)...
  14. Qüesta J, Rius S, Casadevall R, Casati P. ZmMBD101 is a DNA-binding protein that maintains Mutator elements chromatin in a repressive state in maize. Plant Cell Environ. 2016;39:174-84 pubmed publisher
    In maize (Zea mays), as well as in other crops, transposable elements (TEs) constitute a great proportion of the genome...
  15. Liu P, Dong Y, Gu J, Puthiyakunnon S, Wu Y, Chen X. Developmental piRNA profiles of the invasive vector mosquito Aedes albopictus. Parasit Vectors. 2016;9:524 pubmed
    ..69 % of these repeat-derived piRNAs mapped to Class I TEs; 45...
  16. Abd El Hakim Y, Mohamed W, El Metwally A. Spirulina platensis attenuates furan reprotoxicity by regulating oxidative stress, inflammation, and apoptosis in testis of rats. Ecotoxicol Environ Saf. 2018;161:25-33 pubmed publisher
    ..Hematology, sperm count, sperm morphology, serum testosterone (TES), luteinizing hormone (LH), follicle-stimulating hormone (FSH) and estradiol (E2) levels, reduced glutathione (GSH),..
  17. Biryukova I, Ye T. Endogenous siRNAs and piRNAs derived from transposable elements and genes in the malaria vector mosquito Anopheles gambiae. BMC Genomics. 2015;16:278 pubmed publisher
    ..In the medically relevant malaria mosquito Anopheles gambiae TEs constitute 12-16% of the genome size...
  18. Wachter S, Raghavan R, Wachter J, Minnick M. Identification of novel MITEs (miniature inverted-repeat transposable elements) in Coxiella burnetii: implications for protein and small RNA evolution. BMC Genomics. 2018;19:247 pubmed publisher
    ..Like most transposable elements (TEs), MITEs are thought to play an active role in evolution by altering gene function and expression through insertion ..
  19. Robichaud K, Stewart K, Labrecque M, Hijri M, Cherewyk J, Amyot M. An ecological microsystem to treat waste oil contaminated soil: Using phytoremediation assisted by fungi and local compost, on a mixed-contaminant site, in a cold climate. Sci Total Environ. 2019;672:732-742 pubmed publisher
    ..because of slower degradation rates, slower production of biomass for phytoextraction of trace elements (TEs), and remoteness, which can complicate logistics and inflate costs...
  20. Perusquía M, Hanson A, Meza C, Kubli C, Herrera N, Stallone J. Antihypertensive responses of vasoactive androgens in an in vivo experimental model of preeclampsia. J Steroid Biochem Mol Biol. 2018;178:65-72 pubmed publisher
    Dehydroepiandrosterone (DHEA), testosterone (TES) and its 5-reduced metabolites induce a nongenomic vasorelaxation in several vascular beds of mammals; similarly these hormones produce systemic hypotensive and antihypertensive responses ..
  21. Luther I, Jakop U, Lueders I, Tordiffe A, Franz C, Schiller J, et al. Semen cryopreservation and radical reduction capacity of seminal fluid in captive African lion (Panthera leo). Theriogenology. 2017;89:295-304 pubmed publisher
    ..A lyophilized extender (a modified egg yolk-Tes-Tris-fructose-glycerol medium) was rehydrated and added in one step at ambient temperature (?25 °C) to semen, ..
  22. Beaudon E, Gabrielli P, Sierra Hernández M, Wegner A, Thompson L. Central Tibetan Plateau atmospheric trace metals contamination: A 500-year record from the Puruogangri ice core. Sci Total Environ. 2017;601-602:1349-1363 pubmed publisher
    ..of ice core (1497-1992) from the Puruogangri ice cap has been analyzed at high resolution for 28 trace elements (TEs: Ag, Al, As, Ba, Bi, Cd, Co, Cr, Cs, Cu, Fe, Ga, Li, Mg, Mn, Na, Nb, Ni, Pb, Rb, Sb, Sn, Sr, Ti, Tl, U, V and Zn) ..
  23. Forestan C, Farinati S, Aiese Cigliano R, Lunardon A, Sanseverino W, Varotto S. Maize RNA PolIV affects the expression of genes with nearby TE insertions and has a genome-wide repressive impact on transcription. BMC Plant Biol. 2017;17:161 pubmed publisher
    ..required for normal plant development, paramutation, transcriptional repression of certain transposable elements (TEs) and transcriptional regulation of specific alleles...
  24. Isbel L, Srivastava R, Oey H, Spurling A, Daxinger L, Puthalakath H, et al. Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome. PLoS Genet. 2015;11:e1005693 pubmed publisher
    Transposable elements (TEs) have been active in the mammalian genome for millions of years and the silencing of these elements in the germline is important for the survival of the host...
  25. Shashikumar N, Baithalu R, Bathla S, Ali S, Rawat P, Kumaresan A, et al. Global proteomic analysis of water buffalo (Bubalus bubalis) saliva at different stages of estrous cycle using high throughput mass spectrometry. Theriogenology. 2018;110:52-60 pubmed publisher
    ..protein 1, Heat shock 70 kDa protein 1A, 17-beta-hydroxysteroid dehydrogenase type 1, Inhibin beta A chain, testin were identified as estrus specific and are important for estrus physiology...
  26. Antal A, Alekseichuk I, Bikson M, Brockmoller J, Brunoni A, Chen R, et al. Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines. Clin Neurophysiol. 2017;128:1774-1809 pubmed publisher
    Low intensity transcranial electrical stimulation (TES) in humans, encompassing transcranial direct current (tDCS), transcutaneous spinal Direct Current Stimulation (tsDCS), transcranial alternating current (tACS), and transcranial ..
  27. Knower K, Kelly S, Ludbrook L, Bagheri Fam S, Sim H, Bernard P, et al. Failure of SOX9 regulation in 46XY disorders of sex development with SRY, SOX9 and SF1 mutations. PLoS ONE. 2011;6:e17751 pubmed publisher
    ..is under the transcriptional control of SRY, SF1 and SOX9 via a conserved testis-specific enhancer of Sox9 (TES). Regulation of SOX9 in human sex determination is however poorly understood...
  28. García Flórez L, Otero Díez J. Local excision by transanal endoscopic surgery. World J Gastroenterol. 2015;21:9286-96 pubmed publisher
    Transanal endoscopic surgery (TES) consists of a series of anorectal surgical procedures using different devices that are introduced into the anal canal. TES has been developed significantly since it was first used in the 1980s...
  29. Durruthy Durruthy J, Sebastiano V, Wossidlo M, Cepeda D, Cui J, Grow E, et al. The primate-specific noncoding RNA HPAT5 regulates pluripotency during human preimplantation development and nuclear reprogramming. Nat Genet. 2016;48:44-52 pubmed publisher
    ..are derived from thousands of loci in mammalian genomes and are frequently enriched in transposable elements (TEs)...
  30. Boex C, Haemmerli J, Momjian S, Schaller K. Prognostic Values of Motor Evoked Potentials in Insular, Precental, or Postcentral Resections. J Clin Neurophysiol. 2016;33:51-9 pubmed publisher
    ..performed in 104 patients with continuous MEPs elicited with direct cortical and/or transcranial stimulation (DCS, TES; alarm criterion: reproducible 50% decrease in the MEP amplitudes)...
  31. Salame K, Maimon S, Regev G, Kimchi T, Korn A, Mangel L, et al. Electrophysiological monitoring during preoperative angiography to guide decisions regarding permanent occlusion of major radicular arteries in patients undergoing total en bloc spondylectomy. Neurosurg Focus. 2016;41:E19 pubmed publisher
    ..monitoring during preoperative angiography in patients scheduled for total en bloc spondylectomy (TES) of spine tumors improves the safety of vessel occlusion...
  32. Keidar D, Doron C, Kashkush K. Genome-wide analysis of a recently active retrotransposon, Au SINE, in wheat: content, distribution within subgenomes and chromosomes, and gene associations. Plant Cell Rep. 2018;37:193-208 pubmed publisher
    ..The impact of transposable elements (TEs) on genome structure and function is intensively studied in eukaryotes, especially in plants where TEs can reach up ..
  33. Kasuga T, Kozanitas M, Bui M, Hüberli D, Rizzo D, Garbelotto M. Phenotypic diversification is associated with host-induced transposon derepression in the sudden oak death pathogen Phytophthora ramorum. PLoS ONE. 2012;7:e34728 pubmed publisher
    ..Microarray global mRNA profiling detected derepression of transposable elements (TEs) and down-regulation of crinkler effector homologs (CRNs) in the majority of isolates originating from coast live ..
  34. Juras V, Bohndorf K, Heule R, Kronnerwetter C, Szomolanyi P, Hager B, et al. A comparison of multi-echo spin-echo and triple-echo steady-state T2 mapping for in vivo evaluation of articular cartilage. Eur Radiol. 2016;26:1905-12 pubmed publisher
    To assess the clinical relevance of T2 relaxation times, measured by 3D triple-echo steady-state (3D-TESS), in knee articular cartilage compared to conventional multi-echo spin-echo T2-mapping...
  35. Moran S, Chi T, Prucha M, Agca Y, Chan A. Cryotolerance of Sperm from Transgenic Rhesus Macaques (Macaca mulatta). J Am Assoc Lab Anim Sci. 2016;55:520-4 pubmed
    ..EQ) preserved the acrosome better, with less net damage, than did traditional TEST (egg yolk extender containing TES and Tris) media. In addition, the percentage of membrane-damaged cells was similar in fresh HD semen (38.6%±2...
  36. Gao B, Wang S, Wang Y, Shen D, Xue S, Chen C, et al. Low diversity, activity, and density of transposable elements in five avian genomes. Funct Integr Genomics. 2017;17:427-439 pubmed publisher
    In this study, we conducted the activity, diversity, and density analysis of transposable elements (TEs) across five avian genomes (budgerigar, chicken, turkey, medium ground finch, and zebra finch) to explore the potential reason of ..
  37. Lai X, Schnable J, Liao Z, Xu J, Zhang G, Li C, et al. Genome-wide characterization of non-reference transposable element insertion polymorphisms reveals genetic diversity in tropical and temperate maize. BMC Genomics. 2017;18:702 pubmed publisher
    ..In total, 274,408 non-redundant TEs (NRTEs) were identified using resequencing data generated from 83 maize inbred lines...
  38. Engels M, Span P, Mitchell R, Heuvel J, Marijnissen van Zanten M, van Herwaarden A, et al. GATA transcription factors in testicular adrenal rest tumours. Endocr Connect. 2017;6:866-875 pubmed publisher
    ..b>tes)...
  39. Kirkland T, Muszewska A, Stajich J. Analysis of Transposable Elements in Coccidioides Species. J Fungi (Basel). 2018;4: pubmed publisher
    ..The TEs were clustered and the distribution is enriched for the ends on contigs. Analysis of gene expression data from C...
  40. Anderson S, Springer N. Potential roles for transposable elements in creating imprinted expression. Curr Opin Genet Dev. 2018;49:8-14 pubmed publisher
    ..We discuss the evidence for frequent turnover of imprinted expression based on evolutionary analyses in plants and the potential role for transposable elements (TEs) in creating imprinted expression patterns.
  41. Mondal P, de Alcântara Mendes R, Jonathan M, Biswas J, Murugan K, Sarkar S. Seasonal assessment of trace element contamination in intertidal sediments of the meso-macrotidal Hooghly (Ganges) River Estuary with a note on mercury speciation. Mar Pollut Bull. 2018;127:117-130 pubmed publisher
    The spatial and seasonal distribution of trace elements (TEs) (n=16) in surficial sediment were examined along the Hooghly River Estuary (~175km), India...
  42. Xu W, Yang T, Dong X, Li D, Liu A. Genomic DNA Methylation Analyses Reveal the Distinct Profiles in Castor Bean Seeds with Persistent Endosperms. Plant Physiol. 2016;171:1242-58 pubmed publisher
    ..the 24-nucleotide siRNAs played a critical role in maintaining CHH methylation and repressing the activation of TEs in persistent endosperm development...
  43. Panaud O. Horizontal transfers of transposable elements in eukaryotes: The flying genes. C R Biol. 2016;339:296-9 pubmed publisher
    Transposable elements (TEs) are the major components of eukaryotic genomes...
  44. Garcia Perez J, Widmann T, Adams I. The impact of transposable elements on mammalian development. Development. 2016;143:4101-4114 pubmed
    Despite often being classified as selfish or junk DNA, transposable elements (TEs) are a group of abundant genetic sequences that have a significant impact on mammalian development and genome regulation...
  45. Jones B, Wood J, Chang C, Tam A, Franklin M, Siegel E, et al. A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan. Nat Commun. 2016;7:13856 pubmed publisher
    ..RNAs complexed with argonaute proteins to suppress parasitic mobile sequences of DNA called transposable elements (TEs)...
  46. Liu Y, El Kassaby Y. Landscape of Fluid Sets of Hairpin-Derived 21-/24-nt-Long Small RNAs at Seed Set Uncovers Special Epigenetic Features in Picea glauca. Genome Biol Evol. 2017;9:82-92 pubmed publisher
    ..unique genes in Picea, suggestive of their potential pathway in DNA methylation modifications on, for instance, TEs. Additionally, the classification of computationally predicted sRNAs suggests that 24-nt sRNA targets may bear ..
  47. Bell L, Does M, Stokes A, Baxter L, Schmainda K, Dueck A, et al. Optimization of DSC MRI Echo Times for CBV Measurements Using Error Analysis in a Pilot Study of High-Grade Gliomas. AJNR Am J Neuroradiol. 2017;38:1710-1715 pubmed publisher
    ..Optimized TEs were calculated with propagation of error analysis for high-grade glial tumors, normal-appearing white matter, and ..
  48. Hassoune H, Lahhit M, Khalid A, Lachehab A. Application of leaching tests on phosphogypsum by infiltration-percolation. Water Sci Technol. 2017;76:1844-1851 pubmed publisher
    ..Although, this storage can cause an environmental impact largely due to the transfer of trace elements (TEs) to groundwater by leaching...
  49. Jeong J, Rhee J, Kim T, Kwak S, Bang S, Cho H, et al. The association between the nicotinic acetylcholine receptor α4 subunit gene (CHRNA4) rs1044396 and Internet gaming disorder in Korean male adults. PLoS ONE. 2017;12:e0188358 pubmed publisher
    ..We designed targeted exome sequencing (TES) to test for 72 candidate genes that have been implicated in the pathogenesis of addiction...
  50. Kejnovský E, Michalovova M, Steflova P, Kejnovská I, Manzano S, Hobza R, et al. Expansion of microsatellites on evolutionary young Y chromosome. PLoS ONE. 2013;8:e45519 pubmed publisher
    ..We also found that the abundance of microsatellites is higher in the neighborhood of transposable elements (TEs) suggesting that microsatellites are probably targets for TE insertions...
  51. Kim S, Marsch L, Guarino H, Acosta M, Aponte Melendez Y. Predictors of outcome from computer-based treatment for substance use disorders: Results from a randomized clinical trial. Drug Alcohol Depend. 2015;157:174-8 pubmed publisher
    ..maintenance treatment or reduced standard treatment combined with the computer-based therapeutic education system (TES). An array of demographic and behavioral characteristics of participants (N=160) was measured at baseline...
  52. Rius N, Guillén Y, Delprat A, Kapusta A, FESCHOTTE C, Ruiz A. Exploration of the Drosophila buzzatii transposable element content suggests underestimation of repeats in Drosophila genomes. BMC Genomics. 2016;17:344 pubmed publisher
    ..Transposable elements (TEs), being repetitive sequences, are often misassembled, especially in the genomes sequenced with short reads...
  53. Flores Soto E, Reyes García J, Carbajal García A, Campuzano González E, Perusquía M, Sommer B, et al. Sex steroids effects on guinea pig airway smooth muscle tone and intracellular Ca2+ basal levels. Mol Cell Endocrinol. 2017;439:444-456 pubmed publisher
    Testosterone (TES), other androgens and female sex steroids induce non-genomic rapid relaxing effects in airway smooth muscle (ASM)...
  54. Castanera R, Borgognone A, Pisabarro A, Ramirez L. Biology, dynamics, and applications of transposable elements in basidiomycete fungi. Appl Microbiol Biotechnol. 2017;101:1337-1350 pubmed publisher
    ..Transposable elements (TEs) are abundant components of most eukaryotic genomes, and their transition from being genomic parasites to key ..
  55. Karakülah G, Suner A. PlanTEnrichment: A tool for enrichment analysis of transposable elements in plants. Genomics. 2017;109:336-340 pubmed publisher
    Transposable elements (TEs) are mobile DNA sequences that play roles in gene regulation, and have a potential to influence the expression of nearby genes by functioning as cis-regulatory sequences...
  56. Bestmann S, Walsh V. Transcranial electrical stimulation. Curr Biol. 2017;27:R1258-R1262 pubmed publisher
    Transcranial electrical stimulation (tES) is a neuromodulatory technique in which low voltage constant or alternating currents are applied to the human brain via scalp electrodes...
  57. Venetsky A, Levy Zamir A, Khasdan V, Domb K, Kashkush K. Structure and extent of DNA methylation-based epigenetic variation in wild emmer wheat (T. turgidum ssp. dicoccoides) populations. BMC Plant Biol. 2015;15:200 pubmed publisher
    ..to assess the methylation status of random genomic CCGG sites and CCGG sites flanking transposable elements (TEs), respectively...
  58. Fu Y, Xiao M, Yu H, Mason A, Yin J, Li J, et al. Small RNA changes in synthetic Brassica napus. Planta. 2016;244:607-22 pubmed publisher
    ..napus. The percentage of miRNAs derived from transposable elements (TEs) also increased, indicating transposon activation and increased transposon-associated miRNA production in response ..
  59. Rayan N, del Rosario R, Prabhakar S. Massive contribution of transposable elements to mammalian regulatory sequences. Semin Cell Dev Biol. 2016;57:51-56 pubmed publisher
    Barbara McClintock discovered the existence of transposable elements (TEs) in the late 1940s and initially proposed that they contributed to the gene regulatory program of higher organisms...
  60. Wang X, Zhao F, Lv Z, Shi W, Zhang L, Yan M. Triptolide disrupts the actin-based Sertoli-germ cells adherens junctions by inhibiting Rho GTPases expression. Toxicol Appl Pharmacol. 2016;310:32-40 pubmed publisher
    ..As a result of ?-actin down-regulation, TP treatment increased expression of testin, which indicating ES has been disassembled...
  61. Kim S, Kim A, Kim N, Lee C, Han J, Kim M, et al. Functional characterization of a novel loss-of-function mutation of PRPS1 related to early-onset progressive nonsyndromic hearing loss in Koreans (DFNX1): Potential implications on future therapeutic intervention. J Gene Med. 2016;18:353-358 pubmed publisher
    ..Molecular genetic testing, including targeted exome sequencing (TES) of 129 genes for deafness, and in silico prediction were performed. A strong candidate variant (p...
  62. Law J, Chowdhury S, Saim A, Idrus R. Platelet-rich plasma with keratinocytes and fibroblasts enhance healing of full-thickness wounds. J Tissue Viability. 2017;26:208-215 pubmed publisher
    Advances in tissue engineering led to the development of various tissue-engineered skin substitutes (TESS) for the treatment of skin injuries...
  63. Ninova M, Griffiths Jones S, Ronshaugen M. Abundant expression of somatic transposon-derived piRNAs throughout Tribolium castaneum embryogenesis. Genome Biol. 2017;18:184 pubmed publisher
    ..is best understood in the ovary of Drosophila melanogaster, where it acts to silence active transposable elements (TEs)...
  64. Min X, Zhu T, Han J, Li Y, Meng X. Left atrial appendage obliteration in atrial fibrillation patients undergoing bioprosthetic mitral valve replacement. Herz. 2016;41:87-94 pubmed publisher
    ..The main outcome measure was the occurrence of thrombosis events (TEs). The mean follow-up time was 40 ± 17 months...
  65. Kale A, Kumar G, Kapur M. Palladium-catalyzed synthesis of 2-alkenyl-3-arylindoles via a dual α-arylation strategy: formal synthesis of the antilipemic drug fluvastatin. Org Biomol Chem. 2015;13:10995-1002 pubmed publisher
    ..The strategy comprises palladium-catalyzed dual α-arylation of TES-enol ethers of enones as the key step...
  66. Li S, Zhang G, Zhang X, Yuan J, Deng C, Gu L, et al. DPTEdb, an integrative database of transposable elements in dioecious plants. Database (Oxford). 2016;2016: pubmed publisher
    ..Transposable elements (TEs) are mobile DNA elements frequently found in plants and are suggested to play important roles in plant sex ..
  67. Sciubba D, De la Garza Ramos R, Goodwin C, Xu R, Bydon A, Witham T, et al. Total en bloc spondylectomy for locally aggressive and primary malignant tumors of the lumbar spine. Eur Spine J. 2016;25:4080-4087 pubmed
    To report outcomes after total en bloc spondylectomy (TES) for primary aggressive/malignant tumors of the lumbar spine. We performed a retrospective review of 23 neurosurgical patients operated between 2004 and 2014...
  68. Penndorf D, Tadic V, Witte O, Grosskreutz J, Kretz A. DNA strand breaks and TDP-43 mislocation are absent in the murine hSOD1G93A model of amyotrophic lateral sclerosis in vivo and in vitro. PLoS ONE. 2017;12:e0183684 pubmed publisher
    ..In this regard, uncontrolled activation of transposable elements (TEs) might contribute to DNA disintegration and neurodegeneration...
  69. Bikson M, Paneri B, Mourdoukoutas A, Esmaeilpour Z, Badran B, Azzam R, et al. Limited output transcranial electrical stimulation (LOTES-2017): Engineering principles, regulatory statutes, and industry standards for wellness, over-the-counter, or prescription devices with low risk. Brain Stimul. 2018;11:134-157 pubmed publisher
    ..non-invasive electrical brain stimulation devices classified as limited output transcranial electrical stimulation (tES)...
  70. Tai P, Wu H, van Wijnen A, Stein G, Stein J, Lian J. Genome-wide DNase hypersensitivity, and occupancy of RUNX2 and CTCF reveal a highly dynamic gene regulome during MC3T3 pre-osteoblast differentiation. PLoS ONE. 2017;12:e0188056 pubmed publisher
    ..differentially expressed genes that harbor DHS peaks centered within 1 kb downstream of transcriptional end sites (TES)...
  71. Rey O, Danchin E, Mirouze M, Loot C, Blanchet S. Adaptation to Global Change: A Transposable Element-Epigenetics Perspective. Trends Ecol Evol. 2016;31:514-526 pubmed publisher
    ..Here, we highlight the relevance of two environment-sensitive molecular elements: transposable elements (TEs) and epigenetic components (ECs)...
  72. Martinez G, Köhler C. Role of small RNAs in epigenetic reprogramming during plant sexual reproduction. Curr Opin Plant Biol. 2017;36:22-28 pubmed publisher
    ..The latter are derived from transposable elements (TEs) and involved in genome defense and transgenerational inheritance of heterochromatin identity, ensuring genome ..
  73. Li Y, Chang M, Ding S, Wang S, Ni D, Hu H. Monitoring and source apportionment of trace elements in PM2.5: Implications for local air quality management. J Environ Manage. 2017;196:16-25 pubmed publisher
    ..Thirteen trace elements (TEs) in PM2.5 were analyzed by online X-ray fluorescence (XRF). The annual average PM2...
  74. Campbell A, Montgomery L, Sanchez K, Pavlicova M, Hu M, Newville H, et al. Racial/ethnic subgroup differences in outcomes and acceptability of an Internet-delivered intervention for substance use disorders. J Ethn Subst Abuse. 2017;16:460-478 pubmed publisher
    The Therapeutic Education System (TES), an Internet version of the Community Reinforcement Approach plus prize-based motivational incentives, is one of few empirically supported technology-based interventions...
  75. Jangam D, FESCHOTTE C, BETRAN E. Transposable Element Domestication As an Adaptation to Evolutionary Conflicts. Trends Genet. 2017;33:817-831 pubmed publisher
    Transposable elements (TEs) are selfish genetic units that typically encode proteins that enable their proliferation in the genome and spread across individual hosts...
  76. Eagle M, Man J, Rooney P, McQuillan T, Galea G, Kearney J. Assessment of a closed wash system developed for processing living donor femoral heads. Cell Tissue Bank. 2017;18:547-554 pubmed publisher
    NHS Blood and Transplant Tissue and Eye Services (TES) and Scottish National Blood Transfusion Services Tissues and Cells Directorate (TCD) currently bank whole, frozen femoral head bone from living donors who are undergoing primary hip ..
  77. Arkhipova I. Using bioinformatic and phylogenetic approaches to classify transposable elements and understand their complex evolutionary histories. Mob DNA. 2017;8:19 pubmed publisher
    In recent years, much attention has been paid to comparative genomic studies of transposable elements (TEs) and the ensuing problems of their identification, classification, and annotation...
  78. Lau A, Mruk D. Rab8B GTPase and junction dynamics in the testis. Endocrinology. 2003;144:1549-63 pubmed
    ..Taken collectively, these studies suggest that Rab8B participates in adherens junction dynamics in the testis. ..
  79. Yoon H, Kales S, Luo R, Lipkowitz S, Randazzo P. ARAP1 association with CIN85 affects epidermal growth factor receptor endocytic trafficking. Biol Cell. 2011;103:171-84 pubmed publisher
    ..We propose a model in which the ARAP1-CIN85 complex drives exit of EGF-EGFR-Cbl complex from a pre-early endosome into a pathway distinct from the early endosome/lysosome pathway. ..
  80. Mao H, Wang H. SINE_scan: an efficient tool to discover short interspersed nuclear elements (SINEs) in large-scale genomic datasets. Bioinformatics. 2017;33:743-745 pubmed publisher
    Short Interspersed Nuclear Elements (SINEs) are transposable elements (TEs) that amplify through a copy-and-paste mode via RNA intermediates...
  81. Ecco G, Imbeault M, Trono D. KRAB zinc finger proteins. Development. 2017;144:2719-2729 pubmed publisher
    ..with their co-factor KAP1 (also known as TRIM28), in repression of sequences derived from transposable elements (TEs)...
  82. Jo I, Lee J, Hong C, Lee D, Bae W, Park S, et al. Isoform Sequencing Provides a More Comprehensive View of the Panax ginseng Transcriptome. Genes (Basel). 2017;8: pubmed publisher
    ..Finally, transposable elements (TEs) were also identified, suggesting transcriptional activity of TEs in P. ginseng...
  83. Hoffmann W, Folmert K, Moschner J, Huang X, Von Berlepsch H, Koksch B, et al. NFGAIL Amyloid Oligomers: The Onset of Beta-Sheet Formation and the Mechanism for Fibril Formation. J Am Chem Soc. 2017;: pubmed publisher
    ..investigations indicate that presumably soluble hIAPP oligomers are one of the cytotoxic species in type II diabe-tes. Here we use Thioflavin T staining, transmission electron microscopy as well as ion mobility-mass spectrometry ..
  84. Lang D, Ullrich K, Murat F, Fuchs J, Jenkins J, Haas F, et al. The P. patens chromosome-scale assembly reveals moss genome structure and evolution. Plant J. 2017;: pubmed publisher
    ..We find that 57% of the genome comprises transposable elements (TEs), some of which may be actively transposing during the life cycle...
  85. Böhmdorfer G, Sethuraman S, Rowley M, Krzyszton M, Rothi M, Bouzit L, et al. Long non-coding RNA produced by RNA polymerase V determines boundaries of heterochromatin. elife. 2016;5: pubmed publisher
    ..Finally, Pol V transcription is preferentially enriched on edges of silenced transposable elements, where Pol V transcribes into TEs. We propose that Pol V may play an important role in the determination of heterochromatin boundaries.
  86. Ramírez Villaescusa J, Canosa Fernández A, Martin Benlloch A, Ruiz Picazo D, López Torres Hidalgo J. Free disease long-term survival in primary thoracic spine leiomyosarcoma after total en bloc spondylectomy: A case report. Int J Surg Case Rep. 2017;39:332-338 pubmed publisher
    ..For the treatment of primary tumors, total en bloc spondylectomy (TES) is the technique of choice to achieve marginal or wide tumor resection, decrease the risk of local recurrence and ..
  87. Narbey D, Habibi A, Chadebech P, Mekontso Dessap A, Khellaf M, Lelievre J, et al. Incidence and predictive score for delayed hemolytic transfusion reaction in adult patients with sickle cell disease. Am J Hematol. 2017;92:1340-1348 pubmed publisher
    ..We included 694 transfusion episodes (TEs) in 311 patients, divided into occasional TEs (OTEs: 360) and chronic transfusion program (CTEs: 334)...
  88. Noto T, Mochizuki K. Whats, hows and whys of programmed DNA elimination in Tetrahymena. Open Biol. 2017;7: pubmed publisher
    ..flexible epigenetic genome regulations and important insights into the interaction between transposable elements (TEs) and host genomes...
  89. Maeda K, Koga T, Akagi J. Interferential current sensory stimulation, through the neck skin, improves airway defense and oral nutrition intake in patients with dysphagia: a double-blind randomized controlled trial. Clin Interv Aging. 2017;12:1879-1886 pubmed publisher
    ..However, the beneficial effects of transcutaneous electrical sensory stimulation (TESS), without muscle contraction, are controversial...
  90. Qadir M, Usman M, Akash M. Transposable Elements (Human Endogenous Retroviruses) in Cancer. Crit Rev Eukaryot Gene Expr. 2017;27:219-227 pubmed publisher
    Transposable elements (TEs) have shown a great significance in regulatory elements research, being responsible for different types of cancers...
  91. Wardle M, Vincent J, Suchting R, Green C, Lane S, Schmitz J. Anhedonia Is Associated with Poorer Outcomes in Contingency Management for Cocaine Use Disorder. J Subst Abuse Treat. 2017;72:32-39 pubmed publisher
    ..Treatment Effectiveness Score (TES) was defined as the total number of cocaine-negative urines submitted...
  92. Tain R, Scotti A, Li W, Zhou X, Cai K. Influence of Free Radicals on the Intrinsic MRI Relaxation Properties. Adv Exp Med Biol. 2017;977:73-79 pubmed publisher
    ..inversion recovery sequence with varied inversion times and a multi-echo spin echo sequence with varied echo times (TEs), respectively...