TAS2R7

Summary

Gene Symbol: TAS2R7
Description: taste receptor, type 2, member 7
Alias: T2R7, TRB4, taste receptor family B member 4, taste receptor type 2 member 7, taste receptor, family B, member 4
Species: human

Top Publications

  1. doi Different phenolic compounds activate distinct human bitter taste receptors
    Susana Soares
    Department of Chemistry, University of Porto, Porto, Portugal
    J Agric Food Chem 61:1525-33. 2013
  2. doi Assessment of the presence of chemosensing receptors based on bitter and fat taste in the gastrointestinal tract of young pig
    M Colombo
    University of Bologna, DIPROVAL, 42123 Reggio Emilia, Italy
    J Anim Sci 90:128-30. 2012
  3. ncbi T2Rs function as bitter taste receptors
    J Chandrashekar
    Howard Hughes Medical Institute and Department of Biology, University of California, San Diego, La Jolla 92093, USA
    Cell 100:703-11. 2000
  4. ncbi A family of candidate taste receptors in human and mouse
    H Matsunami
    Howard Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nature 404:601-4. 2000
  5. ncbi A plethora of taste receptors
    S C Kinnamon
    Department of Anatomy and Neurobiology, Colorado State University, Fort Collins 80523, USA
    Neuron 25:507-10. 2000
  6. doi The steroid glycoside H.g.-12 from Hoodia gordonii activates the human bitter receptor TAS2R14 and induces CCK release from HuTu-80 cells
    Boris Le Nevé
    Technical University of Munich, Freising Weihenstephan, Germany
    Am J Physiol Gastrointest Liver Physiol 299:G1368-75. 2010

Scientific Experts

  • S C Kinnamon
  • Susana Soares
  • M Colombo
  • Boris Le Nevé
  • Sophie Thalmann
  • Wolfgang Meyerhof
  • Nuno Mateus
  • Susann Kohl
  • Victor de Freitas
  • P Trevisi
  • G Gandolfi
  • P Bosi
  • J Chandrashekar
  • Robin Gouka
  • Hannelore Daniel
  • Martin Foltz
  • H Matsunami
  • M A Hoon
  • N J Ryba
  • K L Mueller
  • J P Montmayeur
  • W Guo
  • L B Buck
  • E Adler
  • L Feng
  • C S Zuker

Detail Information

Publications6

  1. doi Different phenolic compounds activate distinct human bitter taste receptors
    Susana Soares
    Department of Chemistry, University of Porto, Porto, Portugal
    J Agric Food Chem 61:1525-33. 2013
    ..In contrast, malvidin-3-glucoside and procyanidin trimer stimulated only one receptor, TAS2R7 and TAS2R5, respectively...
  2. doi Assessment of the presence of chemosensing receptors based on bitter and fat taste in the gastrointestinal tract of young pig
    M Colombo
    University of Bologna, DIPROVAL, 42123 Reggio Emilia, Italy
    J Anim Sci 90:128-30. 2012
    ..For 7 genes for bitter taste (TAS2R1, TAS2R3, TAS2R7, TAS2R9, TAS2R10, TAS2R16, and TAS2R38) and for 3 genes for fat taste (GPR40, GPR43, and GPR120), a full homology ..
  3. ncbi T2Rs function as bitter taste receptors
    J Chandrashekar
    Howard Hughes Medical Institute and Department of Biology, University of California, San Diego, La Jolla 92093, USA
    Cell 100:703-11. 2000
    ..Since a single taste receptor cell expresses a large repertoire of T2Rs, these findings provide a plausible explanation for the uniform bitter taste that is evoked by many structurally unrelated toxic compounds...
  4. ncbi A family of candidate taste receptors in human and mouse
    H Matsunami
    Howard Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nature 404:601-4. 2000
    ..Another TRB gene is found on a human contig assigned to chromosome 5p15, the location of a genetic locus (PROP) that controls the detection of the bitter compound 6-n-propyl-2-thiouracil in humans...
  5. ncbi A plethora of taste receptors
    S C Kinnamon
    Department of Anatomy and Neurobiology, Colorado State University, Fort Collins 80523, USA
    Neuron 25:507-10. 2000
  6. doi The steroid glycoside H.g.-12 from Hoodia gordonii activates the human bitter receptor TAS2R14 and induces CCK release from HuTu-80 cells
    Boris Le Nevé
    Technical University of Munich, Freising Weihenstephan, Germany
    Am J Physiol Gastrointest Liver Physiol 299:G1368-75. 2010
    ..g.-12 could activate human bitter receptors. The steroid glycoside activated selectively TAS2R7 and TAS2R14, both heterologously expressed in HEK 293 cells...