TAS2R7

Summary

Gene Symbol: TAS2R7
Description: taste receptor, type 2, member 7
Alias: T2R7, TRB4, taste receptor family B member 4, taste receptor type 2 member 7, taste receptor, family B, member 4
Species: human

Top Publications

  1. ncbi T2Rs function as bitter taste receptors
    J Chandrashekar
    Howard Hughes Medical Institute and Department of Biology, University of California, San Diego, La Jolla 92093, USA
    Cell 100:703-11. 2000
  2. ncbi A family of candidate taste receptors in human and mouse
    H Matsunami
    Howard Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nature 404:601-4. 2000
  3. ncbi A plethora of taste receptors
    S C Kinnamon
    Department of Anatomy and Neurobiology, Colorado State University, Fort Collins 80523, USA
    Neuron 25:507-10. 2000
  4. ncbi The steroid glycoside H.g.-12 from Hoodia gordonii activates the human bitter receptor TAS2R14 and induces CCK release from HuTu-80 cells
    Boris Le Nevé
    Technical University of Munich, Freising Weihenstephan, Germany
    Am J Physiol Gastrointest Liver Physiol 299:G1368-75. 2010

Scientific Experts

  • S C Kinnamon
  • Boris Le Nevé
  • J Chandrashekar
  • Hannelore Daniel
  • Martin Foltz
  • H Matsunami
  • Robin Gouka
  • N J Ryba
  • E Adler
  • L B Buck
  • L Feng
  • C S Zuker
  • M A Hoon
  • K L Mueller
  • J P Montmayeur
  • W Guo

Detail Information

Publications4

  1. ncbi T2Rs function as bitter taste receptors
    J Chandrashekar
    Howard Hughes Medical Institute and Department of Biology, University of California, San Diego, La Jolla 92093, USA
    Cell 100:703-11. 2000
    ..Since a single taste receptor cell expresses a large repertoire of T2Rs, these findings provide a plausible explanation for the uniform bitter taste that is evoked by many structurally unrelated toxic compounds...
  2. ncbi A family of candidate taste receptors in human and mouse
    H Matsunami
    Howard Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nature 404:601-4. 2000
    ..Another TRB gene is found on a human contig assigned to chromosome 5p15, the location of a genetic locus (PROP) that controls the detection of the bitter compound 6-n-propyl-2-thiouracil in humans...
  3. ncbi A plethora of taste receptors
    S C Kinnamon
    Department of Anatomy and Neurobiology, Colorado State University, Fort Collins 80523, USA
    Neuron 25:507-10. 2000
  4. ncbi The steroid glycoside H.g.-12 from Hoodia gordonii activates the human bitter receptor TAS2R14 and induces CCK release from HuTu-80 cells
    Boris Le Nevé
    Technical University of Munich, Freising Weihenstephan, Germany
    Am J Physiol Gastrointest Liver Physiol 299:G1368-75. 2010
    ..g.-12 could activate human bitter receptors. The steroid glycoside activated selectively TAS2R7 and TAS2R14, both heterologously expressed in HEK 293 cells...